Results 21 to 30 of about 19,800 (242)
Mechanisms of Self-Assembly of Giant Unilamellar Vesicles in the Army Liposome Formulation (ALF) Family of Vaccine Adjuvants [PDF]
PharmaceuticsBackground/Objectives: Army Liposome Formulation with QS21 (ALFQ) is a vaccine adjuvant formulation consisting of liposomes that contain saturated zwitterionic and anionic phospholipids, 55 mol% cholesterol, and small molar amounts of monophosphoryl ...
Calin Nicolescu +4 more
doaj +2 more sources
Engineering Phosphatidylserine Containing Asymmetric Giant Unilamellar Vesicles
MembranesThe plasma membrane lipid distribution is asymmetric, with several anionic lipid species located in its inner leaflet. Among these, phosphatidylserine (PS) plays a crucial role in various important physiological functions.
Jake McDonough +5 more
doaj +3 more sources
Induced phagocytic particle uptake into a giant unilamellar vesicle.
Soft Matter, 2014 Phagocytosis, the uptake and ingestion of solid particles into living cells, is a central mechanism of our immune system. Due to the complexity of the uptake mechanism, the different forces involved in this process are only partly understood.
A. Meinel +3 more
semanticscholar +5 more sources
Structural and Functional Effects of the Interaction Between an Antimicrobial Peptide and Its Analogs with Model Bacterial and Erythrocyte Membranes [PDF]
BiomoleculesAntimicrobial peptides (AMPs) are a primary defense against pathogens. Here, we examined the interaction of two BP100 analogs, R2R5-BP100 (where Arg substitutes Lys 2 and 5) and R2R5-BP100-A-NH-C16 (where an Ala and a C16 hydrocarbon chain are added to ...
Michele Lika Furuya +12 more
doaj +2 more sources
Facile generation of giant unilamellar vesicles using polyacrylamide gels [PDF]
Scientific Reports, 2020 Giant unilamellar vesicles (GUVs) are model cell-sized systems that have broad applications including drug delivery, analysis of membrane biophysics, and synthetic reconstitution of cellular machineries.
Eric Parigoris +7 more
semanticscholar +6 more sources
Small Methods, 2023 Creating an artificial cell from the bottom up is a long‐standing challenge and, while significant progress has been made, the full realization of this goal remains elusive.
Lori van de Cauter +3 more
semanticscholar +1 more source
Membranes, 2022 Yeast S. cerevisiae has been shown to suppress a sterol biosynthesis as a response to hyperosmotic stress. In the case of sodium stress, the failure to suppress biosynthesis leads to an increase in cytosolic sodium. The major yeast sterol, ergosterol, is
Svyatoslav S. Sokolov +8 more
doaj +1 more source
Asymmetric Giant Unilamellar Vesicles [PDF]
Biophysical Journal, 2010 The lipid composition of the eukaryotic plasma membrane is asymmetric; that is, if the bilayer is considered to consist of two leaflets, the outer-facing leaflet contains different lipids at different concentrations than the inner-facing leaflet. While there has been much speculation as to the physiological purpose of this asymmetry, it has been ...
Hu, Peichi C., Malmstadt, Noah
openaire +1 more source
Hierarchical unilamellar vesicles of controlled compositional heterogeneity. [PDF]
PLoS ONE, 2012 Eukaryotic life contains hierarchical vesicular architectures (i.e. organelles) that are crucial for material production and trafficking, information storage and access, as well as energy production. In order to perform specific tasks, these compartments
Maik Hadorn +3 more
doaj +1 more source
A Note on Vestigial Osmotic Pressure
Membranes, 2023 Recent experiments have indicated that at least a part of the osmotic pressure across the giant unilamellar vesicle (GUV) membrane was balanced by the rapid formation of the monodisperse daughter vesicles inside the GUVs through an endocytosis-like ...
Hao Wu +2 more
doaj +1 more source