Results 51 to 60 of about 19,800 (242)

Light-Switchable Membrane Permeability in Giant Unilamellar Vesicles

Pharmaceutics, 2022
In this work, giant unilamellar vesicles (GUVs) were synthesized by blending the natural phospholipid 1-palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine (POPC) with a photoswitchable amphiphile (1) that undergoes photoisomerization upon irradiation with UV-A (E to Z) and blue (Z to E) light.
Albanese, Paola, Cataldini, Simone, Ren, Chloe Z. J., Valletti, Nadia, Brunetti, Jlenia, Chen, Jack, Rossi, Federico   +6 more
openaire   +5 more sources

Dynamics of giant vesicle assembly from thin lipid films

bioRxiv, 2023
Giant unilamellar vesicles (GUVs) are micrometer-scale lipid assemblies that emulate key characteristics of biological cell membranes. GUVs can be obtained when solid-supported thin films of lipids are hydrated in aqueous solutions.
J. Pazzi, A. Subramaniam
semanticscholar   +1 more source

Coupling between pore formation and phase separation in charged lipid membranes [PDF]

, 2015
We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids.
Hamada, Tsutomu, Higuchi, Yuji, Himeno, Hiroki, Ito, Hiroaki, Shimokawa, Naofumi, Takagi, Masahiro   +5 more
core   +2 more sources

DisGUVery: A Versatile Open-Source Software for High-Throughput Image Analysis of Giant Unilamellar Vesicles

bioRxiv, 2022
Giant Unilamellar Vesicles (GUVs) are cell-sized aqueous compartments enclosed by a phospholipid bilayer. Due to their cell-mimicking properties, GUVs have become a widespread experimental tool in synthetic biology to study membrane properties and ...
Lennard van Buren, G. Koenderink, C. Martinez-Torres   +2 more
semanticscholar   +1 more source

Interaction of apolipoprotein A-I in three different conformations with palmitoyl oleoyl phosphatidylcholine vesicles

Journal of Lipid Research, 2002
Interactions of apolipoprotein A-I (apoA-I) with cell membranes appear to be important in the initial steps of reverse cholesterol transport. The objective of this work was to examine the effect of three distinct conformations of apoA-I (lipid-free and ...
M. Alejandra Tricerri, Susana A. Sanchez, Cristina Arnulphi, Diane M. Durbin, Enrico Gratton, Ana Jonas   +5 more
doaj   +1 more source

Stepwise remodeling and subcompartment formation in individual vesicles by three ESCRT-III proteins

iScience, 2023
Summary: The endosomal sorting complex required for transport (ESCRT) is a multi-protein machinery involved in several membrane remodeling processes. Different approaches have been used to resolve how ESCRT proteins scission membranes.
Yunuen Avalos-Padilla, Vasil N. Georgiev, Eleanor Ewins, Tom Robinson, Esther Orozco, Reinhard Lipowsky, Rumiana Dimova   +6 more
doaj   +1 more source

Membrane‐Penetrating Molecular Device Based on a Triplex Containing Acyclic L‐Threoninol Nucleic Acid Functionalized with Cholesterol

Angewandte Chemie, EarlyView.
A membrane‐penetrating molecular device composed of triplex containing cholesterol‐modified acyclic L‐threoninol nucleic acid (L‐aTNA) was achieved. This device is applied to a photo‐triggered signal transduction system functioning on giant unilamellar vesicles. Abstract Membrane‐penetrating molecular devices are valuable biological tools.
Kaifu Liu, Hiroyuki Asanuma, Keiji Murayama   +2 more
wiley   +2 more sources

Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes

Membranes, 2020
Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the membrane interactions of a designed peptide containing a non-natural, synthetic ...
Lucia Sessa, Simona Concilio, Peter Walde, Tom Robinson, Petra S. Dittrich, Amalia Porta, Barbara Panunzi, Ugo Caruso, Stefano Piotto   +8 more
doaj   +1 more source

Selective flow-induced vesicle rupture to sort by membrane mechanical properties [PDF]

, 2015
International audienceVesicle and cell rupture caused by large viscous stresses in ultrasonication is central to biomedical and bioprocessing applications.
Brooks, NJ, Garbin, V, Pommella, A, Seddon, JM   +3 more
core   +2 more sources

Experimental platform for the functional investigation of membrane proteins in giant unilamellar vesicles

bioRxiv, 2021
Giant unilamellar vesicles (GUVs) are micrometer-sized model membrane systems that can be viewed directly under the microscope. They serve as scaffolds for the bottom-up creation of synthetic cells, targeted drug delivery and have been used in many in ...
Nicolas Dolder, P. Mueller, Christoph von Ballmoos   +2 more
semanticscholar   +1 more source