Results 61 to 70 of about 23,127 (230)
Stepwise remodeling and subcompartment formation in individual vesicles by three ESCRT-III proteins
iScience, 2023 Summary: The endosomal sorting complex required for transport (ESCRT) is a multi-protein machinery involved in several membrane remodeling processes. Different approaches have been used to resolve how ESCRT proteins scission membranes.
Yunuen Avalos-Padilla +6 more
doaj +1 more source
Acta Biomaterialia, 2017 One of the greatest challenges for the development of genetic therapies is the efficient targeted delivery of therapeutic nucleic acids. Towards this goal, we have introduced a new engineering initiative in self-assembly of biologically safe and stable ...
A. Tagalakis +9 more
semanticscholar +1 more source
Coupling between pore formation and phase separation in charged lipid membranes [PDF]
, 2015 We investigated the effect of charge on the membrane morphology of giant unilamellar vesicles (GUVs) composed of various mixtures containing charged lipids.
Hamada, Tsutomu +5 more
core +2 more sources
Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes
Membranes, 2020 Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the membrane interactions of a designed peptide containing a non-natural, synthetic ...
Lucia Sessa +8 more
doaj +1 more source
Membrane shape as a reporter for applied forces [PDF]
, 2008 Recent advances have enabled 3-dimensional reconstructions of biological structures in vivo, ranging in size and complexity from single proteins to multicellular structures. In particular, tomography and confocal microscopy have been exploited to capture
Antonny +30 more
core +2 more sources
Measuring Encapsulation Efficiency in Cell-Mimicking Giant Unilamellar Vesicles
ACS Synthetic Biology, 2023 One of the main drivers within the field of bottom-up synthetic biology is to develop artificial chemical machines, perhaps even living systems, that have programmable functionality. Numerous toolkits exist to generate giant unilamellar vesicle-based artificial cells.
Pashiini Supramaniam +7 more
openaire +4 more sources
Antifungal Effect of (+)-Pinoresinol Isolated from Sambucus williamsii
Molecules, 2010 In this study, we investigated the antifungal activity and mechanism of action of (+)-pinoresinol, a biphenolic compound isolated from the herb Sambucus williamsii,used in traditional medicine.
Bomi Hwang +4 more
doaj +1 more source
Shaping Giant Membrane Vesicles in 3D-Printed Protein Hydrogel Cages
, 2020 Giant unilamellar phospholipid vesicles are attractive starting points for constructing minimal living cells from the bottom-up. Their membranes are compatible with many physiologically functional modules and act as selective barriers, while retaining a ...
Eto, H. +5 more
core +1 more source
Influenza A matrix protein M1 induces lipid membrane deformation via protein multimerization [PDF]
, 2019 The matrix protein M1 of the Influenza A virus (IAV) is supposed to mediate viral assembly and budding at the plasma membrane (PM) of infected cells. In order for a new viral particle to form, the PM lipid bilayer has to bend into a vesicle toward the ...
Chiantia, Salvatore +2 more
core +1 more source
Automated analysis of giant unilamellar vesicles using circular Hough transformation [PDF]
Bioinformatics, 2014 Abstract Motivation: In order to obtain statistically relevant results, the study of membrane effects at the single-vesicle level requires the analysis of several hundreds of giant unilamellar vesicles (GUVs), which becomes a very time-consuming task if carried out manually.
Hermann, E. +3 more
openaire +5 more sources