Results 171 to 180 of about 6,262 (195)
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Domain Sorting in Giant Unilamellar Vesicles Adsorbed on Glass
Langmuir, 2021Giant unilamellar vesicles (GUVs) adsorb to a solid surface and rupture to form a planar bilayer patch. These bilayer patches are used to investigate the properties and functions of biological membranes. Therefore, it is crucial to understand the mechanisms of GUV adsorption. In this study, we investigate the adsorption of phase-separated GUVs on glass
Chiho Kataoka-Hamai, Kohsaku Kawakami
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Block copolymers in giant unilamellar vesicles with proteins or with phospholipids
Faraday Discussions, 2013Biocompatible, highly water-soluble, nonionic, amphiphilic block copolymers having different hydrophobic blocks and architectures, but similar molecular size and chemical nature of the hydrophilic blocks, were investigated to check for their ability to form hybrid giant unilamellar vesicles with proteins, and for their interactions with giant ...
Regina, Schöps +4 more
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Interfacial Phases on Giant Unilamellar Vesicles
ASME 2012 Summer Bioengineering Conference, Parts A and B, 2012Lipid nanodomains in cell membranes are believed to play a significant role in a number of critical cellular processes (Elson, et al., 2010). These include, for example, replication processes in enveloped viruses such as bird flu and HIV and signaling mechanisms underlying pathological conditions such as cancer.
Yanfei Jiang +3 more
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Deformation of giant unilamellar vesicles under osmotic stress
Colloids and Surfaces B: Biointerfaces, 2018Biological membrane plays an important role in maintaining an osmotic equilibrium between the cytoplasm and the extracellular solution of cells. Here, the giant unilamellar vesicles (GUVs) as cell models were used to investigate the effect of osmotic stress on phospholipid membranes. The deformation of GUVs, including inward budding and outward budding,
Wei, Zong +3 more
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Methods for Forming Giant Unilamellar Fatty Acid Vesicles
2021Fatty acids readily assemble into bilayer membranes at a pH near their apparent pKa. Fatty acid vesicles are not only useful for research in the fields of origins of life, soft matter science, biophysics, and drug delivery, but are also cost-effective and easy to manipulate, making them ideal for teaching students about self-assembly and lipid bilayers.
Lauren A, Lowe +2 more
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Deformation Modes of Giant Unilamellar Vesicles Encapsulating Biopolymers
ACS Synthetic Biology, 2018The shapes of giant unilamellar vesicles (GUVs) enclosing polymer molecules at relatively high concentration, used as a model cytoplasm, significantly differ from those containing only small molecules. Here, we investigated the effects of the molecular weights and concentrations of polymers such as polyethylene glycol (PEG), bovine serum albumin (BSA),
Taiji Okano +3 more
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Giant Unilamellar Vesicle Microarrays for Cell Function Study
Analytical Chemistry, 2018Giant unilamellar vesicles (GUVs) are widely used as artificial cell models which contribute to elucidate fundamental questions on origin of life and cell functions. Herein, the GUV microarrays were developed using a point-to-plane electrode system combined with microcontact stripping technique.
Chuntao Zhu +3 more
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Trapping and release of giant unilamellar vesicles in microfluidic wells
Soft Matter, 2014We describe the trapping and release of giant unilamellar vesicles (GUVs) in a thin and wide microfluidic channel, as they cross indentations etched in the channel ceiling. This trapping results from the reduction of the membrane elastic energy, which is stored in the GUV as it squeezes to enter into the thin channel.
Yamada, Ayako +3 more
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