Deformation and motion of giant unilamellar vesicles loaded with gold nanoparticles driven by induced charge electro-osmotic flow [PDF]
A vesicle is a spherical structure composed of a phospholipid bilayer that is used as a container for chemicals, both it in vivo and it in vitro systems. In both cases, the vesicles can be passively moved using external molecular motors or flows. The active motion of the vesicles can potentially expand their applications in microfluid devices.
arxiv
High‐Resolution Patterned Delivery of Chemical Signals From 3D‐Printed Picoliter Droplet Networks
3D‐printed picoliter droplet networks have been fabricated that control gene expression in bacterial populations by releasing chemical signals with precise spatial definition and high temporal resolution. This system of effector release is widely applicable, offering diverse applications in biology and medicine.
Jorin Riexinger+7 more
wiley +1 more source
Mechanism of cellular uptake of genotoxic silica nanoparticles. [PDF]
Mechanisms for cellular uptake of nanoparticles have important implications for nanoparticulate drug delivery and toxicity. We have explored the mechanism of uptake of amorphous silica nanoparticles of 14 nm diameter, which agglomerate in culture medium ...
Brown, AP+5 more
core +3 more sources
Induced phagocytic particle uptake into a giant unilamellar vesicle
Phagocytosis, the uptake and ingestion of solid particles into living cells, is a central mechanism of our immune system. Due to the complexity of the uptake mechanism, the different forces involved in this process are only partly understood. Therefore the usage of a giant unilamellar vesicle (GUV) as the simplest biomimetic model for a cell allows one
Meinel, Andreas+3 more
openaire +4 more sources
A Photonastic Prototissue Capable of Photo‐Mechano‐Chemical Transduction
Mimicking energy transduction in prototissue assemblies remains a challenge of bottom‐up synthetic biology. In this work, prototissues integrating protocells with photothermal gold nanoparticle proto‐organelles and a thermoresponsive polymeric proto‐cortex are developed.
Agostino Galanti+7 more
wiley +1 more source
Light‐driven H2 evolution catalysis is reported for oleylamine‐capped MCo Prussian blue analogs (PBAs, M = Ni, Co, Zn, Cu) within phospholipid bilayers and using a ruthenium‐based amphiphilic photosensitizer. The hydrophobic interactions between the active units bring them in close proximity facilitating catalysis.
Subrata Mandal+5 more
wiley +1 more source
Bioinspirierte Kationische Antimikrobielle Polymere
Dieser Übersichtsartikel behandelt Membran‐aktive kationische Polymere mit antimikrobiellen Eigenschaften. Im Fokus stehen Aspekte wie die Polymerarchitektur, Stimuli‐responsive antimikrobielle Polymere sowie Synergien von Polymeren und anderen Verbindungen.
Heliya Javadi+2 more
wiley +1 more source
Determining membrane permeability of giant phospholipid vesicles from a series of videomicroscopy images [PDF]
A technique for determining the permeability of a phospholipid membrane on a single giant unilamellar vesicle (GUV) is described, which complements the existing methods utilizing either a planar black lipid membrane or sub-micrometre-sized liposomes. A single GUV is transferred using a micropipette from a solution of a nonpermeable solute into an iso ...
arxiv +1 more source
A Single‐Molecule Liposome Assay for Membrane Permeabilization
The rapid screening of compounds capable of disrupting or permeabilizing biological membranes is essential to the search for new therapeutics. Here, we present an ultrasensitive single‐molecule confocal microscopy assay combined with fast‐flow microfluidics to study membrane permeabilization in large unilamellar vesicles (LUVs).
Krzysztof M. Bąk+9 more
wiley +1 more source
Phase separation and near-critical fluctuations in two-component lipid membranes: Monte Carlo simulations on experimentally relevant scales [PDF]
By means of lattice-based Monte Carlo simulations, we address properties of two-component lipid membranes on the experimentally relevant spatial scales of order of a micrometer and time intervals of order of a second, using DMPC/DSPC lipid mixtures as a ...
Ehrig, Jens+2 more
core +2 more sources