Results 81 to 90 of about 13,345 (202)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Sphingomyelinase D activity in model membranes: structural effects of in situ generation of ceramide-1-phosphate. [PDF]

PLoS ONE, 2012
The toxicity of Loxosceles spider venom has been attributed to a rare enzyme, sphingomyelinase D, which transforms sphingomyelin to ceramide-1-phosphate. The bases of its inflammatory and dermonecrotic activity, however, remain unclear.
Roberto P Stock, Jonathan Brewer, Kerstin Wagner, Blanca Ramos-Cerrillo, Lars Duelund, Kit Drescher Jernshøj, Lars Folke Olsen, Luis A Bagatolli   +7 more
doaj   +1 more source

Law of corresponding states for osmotic swelling of vesicles

, 2012
As solute molecules permeate into a vesicle due to a concentration difference across its membrane, the vesicle swells through osmosis. The swelling can be divided into two stages: (a) an "ironing" stage, where the volume-to-area ratio of the vesicle ...
Angelova, Diamant, Dimova, Dordas, Döbereiner, Emir Haleva, Evans, Farago, Farago, Fournier, Haim Diamant, Haleva, Haleva, Heinrich, Helfrich, Krasteva, Linke, Litster, Mally, Marsh, Milner, Mui, Orbach, Patel, Paula, Peterlin, Peterlin, Pocivavsek, Primož Peterlin, Schmid, Seifert, Vesna Arrigler, Vitkova   +32 more
core   +1 more source

Microcavity supported lipid membranes: versatile platforms for building asymmetric lipid bilayers and for protein recognition [PDF]

, 2019
Microcavity supported lipid bilayers (MSLB) are contact-free membranes suspended across aqueousfilled pores that maintain the lipid bilayer in a highly fluidic state and free from frictional interactions with substrate.
Berselli, Guilherme, Keyes, Tia E., Murphy, Paul V., Ramadurai, Sivaramakrishnan, Sarangi, Nirod Kumar   +4 more
core   +1 more source

Developing giant plasma membrane vesicles from Leishmania cells to investigate the role of membrane proteins in photodynamic inactivation

Photochemistry and Photobiology, EarlyView.
In this study, we developed giant plasma membrane vesicles (GPMVs) from Leishmania amazonensis promastigote membranes to investigate the role of protein‐embedded membranes in methylene blue (MB) photooxidation. Upon MB photoactivation in model lipid membranes (giant unilamellar vesicles, GUVs), a distinct photooxidation effect was observed, marked by ...
Maressa D. F. de Souza, Pietro Ciancaglini, Rosangela Itri, Martha S. Ribeiro   +3 more
wiley   +1 more source

Photo‐Responsive Glyco‐Microfibers: Design, Self‐Assembly, and Morphological Control of Aqueous Microdroplets

ChemSystemsChem, Volume 8, Issue 2, March 2026.
Aqueous self‐assembly of a 2‐nitrobenzyl‐functionalized glucosamine derivative leads to the formation of photo‐responsive glyco‐microfibers via cooperative noncovalent interactions, primarily driven by π–π stacking and hydrogen bonding. Upon photo‐irradiation, the glyco‐microfibers undergo dis‐assembly even within confined water‐in‐oil microdroplets ...
Fumiko Nakagawa, Bioru Okumura, Sayuri L. Higashi, Yushi Shibata, Shintaro Sugiura, Shin‐ichiro Kawano, Hiroshi Katagiri, Masato Ikeda   +7 more
wiley   +1 more source

Study of the Interaction of a Novel Semi-Synthetic Peptide with Model Lipid Membranes

Membranes, 2020
Most linear peptides directly interact with membranes, but the mechanisms of interaction are far from being completely understood. Here, we present an investigation of the membrane interactions of a designed peptide containing a non-natural, synthetic ...
Lucia Sessa, Simona Concilio, Peter Walde, Tom Robinson, Petra S. Dittrich, Amalia Porta, Barbara Panunzi, Ugo Caruso, Stefano Piotto   +8 more
doaj   +1 more source

Zweikanal‐Fluoreszenz‐Assays mit supramolekularen Wirt/Farbstoff‐Reporterpaaren zur Kartierung der Membranaktivität von Peptiden

Angewandte Chemie, Volume 138, Issue 5, 28 January 2026.
Membranaktive Peptide (MAPs) wie zellpenetrierende Peptide (CPPs) und antimikrobielle Peptide (AMPs) können Lipidmembranen durchdringen und Membranporen bilden. Die Kombination aus einem Farbstoff‐Efflux‐Assay und einem supramolekularen Tandem‐Membran‐Assay in einem Zweikanalformat ermöglicht eine fortgeschrittene mechanistische Charakterisierung und ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source

Direct measurement of DNA-mediated adhesion between lipid bilayers

, 2015
Multivalent interactions between deformable mesoscopic units are ubiquitous in biology, where membrane macromolecules mediate the interactions between neighbouring living cells and between cells and solid substrates.
Cicuta, P., Di Michele, L., Mognetti, B. M., Orsi, D., Parolini, L., Shimobayashi, S. F.   +5 more
core   +1 more source

Dual‐Channel Fluorescence Assays with Supramolecular Host‐Dye Reporter Pairs for Membrane Activity Mapping of Peptides

Angewandte Chemie International Edition, Volume 65, Issue 5, 28 January 2026.
Membrane‐active peptides (MAPs) such as cell‐penetrating peptides (CPPs) and antimicrobial peptides (AMPs) can translocate across lipid membranes and create membrane pores. The combination of a dye efflux and a supramolecular tandem membrane assay in a dual‐channel format enables an advanced mechanistic characterization and an exploration of the ...
Mohammad A. Alnajjar, Sandra N. Schöpper, Malavika Pramod, Thomas Reingolz, Lina Müller, Justin Neumann, Mohamed Nilam, Werner M. Nau, Andreas Hennig   +8 more
wiley   +1 more source