Results 161 to 170 of about 2,070,727 (280)

From Membrane Composition to Antimicrobial Strategies: Experimental and Computational Approaches to AMP Design and Selectivity

Small, EarlyView.
Antimicrobial peptides (AMPs) are promising candidates for next‐generation antibiotics, acting through mechanisms such as membrane disruption and intracellular targeting. This review examines how variations in bacterial membrane composition critically influence AMP activity.
Paolo Rossetti, Marius F.W. Trollmann, Christina Wichmann, Thomas Gutsmann, Christian Eggeling, Rainer A. Böckmann   +5 more
wiley   +1 more source

Separation of Magnetic Microparticles With Different Molecular Surface Functionalizations by Close‐to‐Surface Traveling‐Wave Magnetophoresis

Small, EarlyView.
Inducing surface‐near magnetic particle transport inside a static liquid via an engineered, dynamic potential energy landscape, different chemical surface properties of otherwise identical particles can be distinguished using simple optical observation.
Yahya Shubbak, Katharina Eichhorn, Nikolai Weidt, Arne Vereijken, Rico Huhnstock, Arno Ehresmann   +5 more
wiley   +1 more source

Mimivirus transcription and translation occur at well-defined locations within amoeba host cells

Journal of Virology
Many giant viruses replicate in the cytoplasm in viral factories. How exactly these viral factories are established and where the different steps of the replication cycle occur remain largely obscure.
Lotte Mayer, Georgi Nikolov, Martin Kunert, Matthias Horn, Anouk Willemsen   +4 more
doaj   +1 more source

“Bad Things Happen in Philadelphia”: Managing Stigma and Threats in the Wake of False Criminal Accusations

Symbolic Interaction, EarlyView.
In the aftermath of the 2020 U.S. election, the boundary between activism and extremism blurred, with election officials reporting violent threats and false accusations of election fraud. From a symbolic interactionist perspective, these attacks provide a unique lens for examining the consequences of being falsely labeled a criminal.
Steven Windisch
wiley   +1 more source

Microarray detection of human parainfluenzavirus 4 infection associated with respiratory failure in an immunocompetent adult. [PDF]

, 2006
A pan-viral DNA microarray, the Virochip (University of California, San Francisco), was used to detect human parainfluenzavirus 4 (HPIV-4) infection in an immunocompetent adult presenting with a life-threatening acute respiratory illness.
Blackburn, Brian G, Chiu, Charles Y, DeRisi, Joseph L, Eckburg, Paul B, Fischer, Kael, Ganem, Don, Koshy, Anita, Merker, Jason D, Patterson, Bruce K, Rouskin, Silvi, Schnurr, David, Tompkins, Lucy S, Urisman, Anatoly, Yagi, Shigeo   +13 more
core  

Iflaviruses in arthropods: when small is mighty

Insect Science, EarlyView.
Many arthropod species harbor iflaviruses, which often cause covert (asymptomatic) infections, but may still affect host fitness. We review the impact of iflaviruses on arthropod fitness, immunity, behaviour as well as the iflavirus’ host range, transmission, tissue tropism and the interactions with other microorganisms within arthropods.
Annamaria Mattia, Hannah‐Isadora Huditz, Monique M. van Oers, Vera I.D. Ros   +3 more
wiley   +1 more source

Microglial reactivity and nodule formation are associated with Synaptodendritic damage in the brains of people with HIV‐1

Brain Pathology, EarlyView.
Despite effective ART, neurocognitive impairment persists in people with HIV. Brains from PWH present exacerbated microgliosis and formation of microglial nodules that are actively engaged in neuronal phagocytosis, resulting in neuronal injury and dendritic loss.
Roberta S. Dos Reis, Lauren A. Ignatz, Sathish Selvam, Marc C. E. Wagner, Sara Gianella, Antoine Chaillon, Vanessa Gomez‐Moreno, Jeremy Martison, Leah H. Rubin, Sabina Heberlen, Valentina Stosor, Jordan Lake, Velpandi Ayyavoo   +12 more
wiley   +1 more source

Unusual Life Style of Giant Chlorella Viruses

Annual Review of Genetics, 2003
▪ Abstract  Paramecium bursaria chlorella virus (PBCV-1) is the prototype of a family of large, icosahedral, plaque-forming, dsDNA viruses that replicate in certain unicellular, eukaryotic chlorella-like green algae. Its 330-kb genome contains ∼373 protein-encoding genes and 11 tRNA genes.
openaire   +3 more sources

Disseminated Papules in a 40‐Year‐Old Man

JEADV Clinical Practice, EarlyView.
E. Bearzi, D. C. Ortiz Jimenez, F. Chersi, S. Sulfaro, D. Signoretto, N. Di Meo, I. Zalaudek   +6 more
wiley   +1 more source

Zebrafish as a model for Catel–Manzke syndrome—identification and characterization of the zebrafish TGDS ortholog

The FEBS Journal, EarlyView.
Zebrafish Tgds, when expressed as a recombinant protein, catalyzes the dehydration of UDP‐D‐glucose, the initial step in the formation of 6‐deoxyhexoses. Corresponding Tgds mutations found in Catel–Manzke syndrome patients lead to reduced enzymatic activity and stability.
Maria Rosaria Coppola, Deianira Bellitto, Erfan Asgari, Virginia Bazzurro, Giorgia Casucci, Francesco Piacente, Matteo Bozzo, Davide Ceresa, Costantino Parisi, Cecilia Winata, Simona Candiani, Michela Tonetti   +11 more
wiley   +1 more source