Results 181 to 190 of about 20,275 (234)
ABSTRACT Adipocyte hypertrophy poses an important mechanical challenge—adipocytes can increase in volume up to a thousand‐fold while still maintaining their structural integrity. Although lipid metabolism is well studied, little is known about the cytoskeletal adaptations that are required to accommodate this expansion and the resulting pathological ...
Dhakshmi Sasankan, Renu Mohan
wiley +1 more source
Mortality involving ischemic heart disease and cardiac arrhythmias declined over two decades before rising sharply during the COVID‐19 pandemic. Significant disparities by sex, race, region, and rurality emphasize the need for equitable cardiovascular prevention and management. ABSTRACT Background Ischemic heart disease (IHD) remains a leading cause of
Taha Alam +13 more
wiley +1 more source
ABSTRACT Background This study aimed to analyze the alterations in cellular and humoral immune functions, alongside cytokine profiles, in patients with recurrent aphthous ulcer (RAU) compared to those with other oral mucosal diseases and healthy controls (HC), and to investigate their clinical significance.
Yiwen Chen +3 more
wiley +1 more source
Abstract Objectives In this case, we present a patient with rapidly progressive unilateral destructive orbital and midface inflammation. Initial detection of Corynebacterium kroppenstedtii was followed by a consistent course of localised necrotizing small‐vessel vasculitis, which was responsive to B‐cell depletion. Methods A 79‐year‐old woman presented
Nadine Al‐Azem +11 more
wiley +1 more source
ABSTRACT Cutaneous manifestations of chronic lymphocytic leukemia (CLL) are heterogeneous and may result from leukemic infiltration, secondary malignancies, infectious complications, or reactive inflammatory processes. Reactive angioendotheliomatosis (RAE) is a rare vascular proliferation that has only infrequently been reported in association with ...
Feras Alfraih +4 more
wiley +1 more source
Environmental and anthropogenic drivers of antibiotic resistance dissemination. The cycle reinforces how anthropogenic inputs, such as sewage, animal dung, hospital effluent, and agricultural runoff bring resistant bacteria and antibiotic residues into soil and water.
Punam Chowdhury +3 more
wiley +1 more source
Macrophage: Biological Functions, Diseases, and Therapeutic Targets
Macrophages are sentinel innate immune cells that arise from embryonic precursors and bone marrow monocytes, displaying a functional continuum that transcends the classical M1 (pro‐inflammatory)/M2 (anti‐inflammatory) dichotomy. Under homeostatic conditions, balanced M1/M2 polarization preserves tissue integrity by coordinating immune surveillance ...
Bihang Sun +4 more
wiley +1 more source
Mycobacterium tuberculosis–host interactions and infection outcomes. Following initial infection, alveolar macrophages phagocytose the pathogen, prompting the recruitment of innate immune cells including neutrophils, NK cells, and interstitial macrophages.
Xiaojuan Zhang +3 more
wiley +1 more source
CoCryoViS: Collaborative online cryo‐electron tomography visualization system
Abstract We present a collaborative, interactive, web‐based visualization and processing system for Cryo‐Electron Tomography (cryo‐ET) data that supports the complete workflow, from raw tilt‐series projections to final 3D segmentations. The system integrates tilt‐series alignment, motion correction, tomographic reconstruction, manual and pseudo ...
Omar Mena +8 more
wiley +1 more source

