Results 41 to 50 of about 5,408 (254)

Delivery of DNA‐encoded vaccines and proteins in mice using cutaneous suction‐mediated transfection

FEBS Open Bio, EarlyView.
Cutaneous suction‐mediated transfection in mice for delivery of DNA‐encoded vaccines and proteins. A critical limitation of DNA vaccines and other therapeutics is transfection in vivo to produce the encoded antigens or therapeutic proteins. Cutaneous suction‐based methods have demonstrated effectiveness in many animal models and have been successfully ...
Emran O. Lallow, Isabel Brandtjen, Yaxin Mo, Melissa Gulley, Louis Osorio, Sagar Kudchodkar, Nandita C. Jhumur, Christine C. Roberts, Lisa K. Denzin, David I. Shreiber, Biju Parekkadan, Hao Lin, Joel N. Maslow   +12 more
wiley   +1 more source

A Depolarizing Leak in Sodium Bicarbonate Cotransporter NBCe1 Causes Brain Edema

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objectives SLC4A4 encodes electrogenic sodium bicarbonate cotransporter NBCe1, prominently expressed in kidney and brain. Recessive loss‐of‐function variants in SLC4A4 cause proximal renal tubular acidosis, no brain edema. In the brain, NBCe1 is expressed by astrocytes, where it regulates pH and mediates astrocyte volume changes.
Quinty Bisseling, Mark D. Parker, Sven Kerst, Richard A. Pasternack, Jacob Tondreau, Marjolein Breur, Gemma M. van Rooijen‐van Leeuwen, Davide Tonduti, Ettore Salsano, Alejandra Darling, Joanna A. E. van Wijk, Susanna Törnroth‐Horsefield, Marianna Bugiani, Petra J. W. Pouwels, Quinten Waisfisz, Marjo S. van der Knaap, Rogier Min   +16 more
wiley   +1 more source

Elevated Connectivity During Language Processing Is Associated With Cognitive Performance in SeLECTS

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Self‐Limited Epilepsy with Centrotemporal Spikes (SeLECTS) is associated with language impairments despite seizures originating in the motor cortex, suggesting aberrant cross‐network interactions. Here we tested whether functional connectivity in SeLECTS during language tasks predicts language performance.
Wendy Qi, Katharine Lee, Kerry C. Nix, Miguel Menchaca, Xiwei Shé, Lorelei Santa Maria, Wei Wu, Zihuai He, Fiona M. Baumer   +8 more
wiley   +1 more source

СОЦІАЛЬНО-ПЕДАГОГІЧНИЙ СУПРОВІД ОБДАРОВАНИХ ДІТЕЙ І МОЛОДІ ЯК ШЛЯХ ГАРМОНІЗАЦІЇ ІНТЕЛЕКТУАЛЬНОГО ТА ЕМОЦІЙНОГО ФАКТОРІВ НАВЧАННЯ

Освітній вимір, 2012
У статті розглядається проблема здійснення соціально-педагогічного супроводу обдарованих дітей і молоді в навчальних закладах як шлях гармонізації інтелектуального та емоційного факторів навчання. Ключові слова: особистість, обдарованість, обдарована
О. Д. Вєтрова
doaj   +1 more source

Clinician and Patient Factors Associated With Long‐Term Glucocorticoid Use in People With Rheumatoid Arthritis Receiving Advanced Therapies

Arthritis Care &Research, EarlyView.
Objective Despite guideline recommendations, long‐term glucocorticoid (GC) use is common in rheumatoid arthritis (RA). We conducted a clinician survey nested within a large registry to identify patient and clinician factors associated with GC use. Methods Clinicians contributing patients to the CorEvitas Rheumatoid Arthritis Registry were surveyed ...
Michael D. George, George Reed, Matthew D. Kearney, Peter F. Cronholm, Kevin Kane, Jeffrey R. Curtis, Dimitrios A. Pappas, Joel M. Kremer   +7 more
wiley   +1 more source

The significance of the teacher's role in the identification and development of giftedness in students [PDF]

Zbornik Radova Filozofskog Fakulteta u Prištini, 2023
At today's level of social development, the prevailing understanding is that every child has the right to education in accordance with their needs and capabilities.
Sekulić Marija R.
doaj  

Mechanically Mutable Matrices: A Hierarchical Investigation of Decellularized Sea Cucumber Collagen as an Adaptable Scaffold Material

Advanced Functional Materials, EarlyView.
Sea cucumber mutable collagenous tissue (MCT) is a remarkable collagen‐based material which can rapidly undergo large changes in stiffness through transiently bound effector proteins. Here, we investigate the hierarchical structure and mechanical response of MCT from Cucumaria frondosa across length scales with a wide range of methods, also exploring ...
Nathalie R. H. Singh, Amy K. Lin, Sabra Rostami, Cameron Hastie, Paul W. Wiseman, Patrick Flammang, Christopher Moraes, Matthew J. Harrington   +7 more
wiley   +1 more source

SOME ASPECTS OF THE HEALTH STATUS OF GIFTED SCHOOL CHILDREN

Acta Biomedica Scientifica, 2012
We surveyed. 112 adolescents aged 14-17 years. This cohort of children was divided into 3 groups: gifted realized, unrealized and secondary gifted intellectuals.
V. V. Dolgikh, L. V. Rychkova, V. M. Polyakov, O. V. Bugun, A. N. Rodionova, A. V. Davidov   +5 more
doaj  

TYPES OF SUPPORT GIFTED STUDENTS RECEIVE IN SCHOOL

Facta Universitatis. Series, Teaching, Learning and Teacher Education, 2019
This paper is oriented towards the attitudes of the teachers and the gifted student parents on types of support gifted students receive in school in addition to extra classes, as well as towards parents’ attitudes on acceleration and special programs as ...
Marija Jovanović, Tamara Vukić
doaj   +1 more source

Indonesian Teachers' Attitudes towards Gifted Students with Low SES from Malay Background

Indonesian Journal of Disability Studies, 2020
Defined as a child who has superior capabilities, especially in the area of intelligence, many gifted children in Indonesia are ignored, especially those who have poverty issues in a rural area like Malay. This is disappointing as some theorists believe
Suhendri, Sri Maryanah, Ediyanto, Kawai Norimune   +3 more
doaj   +1 more source