Results 61 to 70 of about 5,408 (254)
Advanced Science, EarlyView.Inhibition of KDELR2 in a small fraction of tumor cells generates sustainable immunogenic cell death conditions within the tumor microenvironment. These conditions promote the regression of tumors in a T cell independent manner. During regression, macrophages prime T cells that subsequently provide systemic protection against recurrence. The potency of
Shakti P Pattanayak +6 more
wiley +1 more source
Advanced Science, EarlyView.Human neutrophils exist as two epigenetically imprinted subtypes defined by stable CD177 expression or absence — a ratio that persists across time, circadian rhythms, and inflammation. CD177− neutrophils display a distinct molecular landscape enriched in arginase 1 and lipid metabolism markers, accumulate in head‐and‐neck tumors, and associate with ...
Marcel Jung +39 more
wiley +1 more source
К вопросу о проблеме диагностики и развития одаренных детей в условиях взаимодействия «Школа-Вуз»
International Dialogues on Education: Past and Present, 2016 The article deals with the problem of diagnosing gifted children and creating psychological and pedagogical conditions for the intellectual and personal growth of gifted children in secondary schools and higher-education institutions.
Вероника Михайловна Гребенникова +1 more
doaj +1 more source
Advanced Science, EarlyView.eEF1G supports translation elongation of meiotic mRNAs in transcriptionally quiescent leptotene and zygotene spermatocytes. Its depletion in germ cells causes meiotic arrest at the zygotene stage, with defective homologous synapsis and unstable recombination intermediates.
Jianze Xu +12 more
wiley +1 more source
CALB2 is a Mechanoresistance Gene in Metastatic Prostate Cancer
Advanced Science, EarlyView.Prostate cancer cell lines of differing origins were cultured over many passages while being subjected to semi‐lethal levels of fluid shear stress, representing the harsh mechanical environment these cells are subjected to in the circulation during the process of distant metastasis.
Abigail R. Fabiano +10 more
wiley +1 more source
The gifted child: a conceptual enquiry [PDF]
Oxford Review of Education, 2006 The concept of giftedness is frequently challenged on the grounds that 1) it is a ragged or slippery concept, 2) it is inegalitarian, 3) it is culturally arbitrary, and 4) it fails to distinguish children with natural ability from children who are parentally pressured. I argue that all these charges are unfounded.
openaire +3 more sources
A Universal Protein Ladder for Standardization of Diverse FRET Assays
Advanced Science, EarlyView.Translating FRET measurements from in vitro to intracellular environments requires universal benchmarks. We present a modular protein ladder using TPR motifs to harmonize data across diverse platforms. This predictable calibration curve bridges single molecule FRET measurements, with cell based measurements including FLIM‐FRET.
Evelyn R. Smith +5 more
wiley +1 more source
Preparation of teachers for developing education under the program ‘Gifted Child’ by N.B. Shumakova
Russian Journal of Education and PsychologyBackground. This article presents the experience of implementing N.B. Shumakova's program "Gifted Child" in elementary schools. The authors conducted a thorough theoretical analysis and emphasized that the program's core component is creative ...
Vera V. Savelyeva, Yulia T. Antonova
doaj +1 more source
Advanced Science, EarlyView.Super‐multiplexed Label‐free Raman Imaging (SLRI) enables 2D/3D metabolic mapping of intact Drosophila testes. Moving beyond descriptive morphology, it establishes a multidimensional tool for tissue metabolic remodeling, and offers a generalizable platform for complex tissue analysis, with implications extending to development and disease. ABSTRACT The
Jiaxin Li +23 more
wiley +1 more source
Giftedness as a Factor in Constituting a Creative Person
Antropologìčnì Vimìri Fìlosofsʹkih Doslìdžen'Purpose. The basis of the presented study is a philosophical and anthropological analysis of the problem of creativity in the modern educational space, which is complemented by information and digital reality underlying the changes in the values and ...
L. I. Tkachenko, A. A. Ilina
doaj +1 more source