Results 31 to 40 of about 839,935 (220)
NICE: A Two‐Step Non‐Invasive Framework for Embryo cfDNA Read Enrichment and Quality Assessment
Advanced Science, EarlyView.The non‐invasive NICE framework, built on an ensemble stacking machine learning model, prioritizes embryos by analyzing cell‐free DNA from spent culture medium. By integrating multimodal signals, including genomic and epigenetic profiles, this automated approach standardizes morphological assessment without human bias, paving the way for more precise ...
Xueya Zhou +6 more
wiley +1 more source
Molecular and cellular mechanisms of Ginkgo biloba extract [EGb 761®] in improving age-related and ß-amyloid induced neuronal dysfunctions [PDF]
, 2009 The utilization of Ginkgo biloba in medicinal practice dates back to 1505 A.D. Ironically, the mechanisms of action of Ginkgo are not fully clarified till now.
Abdel-Kader, Reham Mahmoud
core
Age-related increase of oxidative stress-induced apoptosis in mice prevention by Ginkgo biloba extract (EGb761) [PDF]
, 2006 Enhanced apoptosis and elevated levels of reactive oxygen species (ROS) play a major role in aging. In addition, several neurodegenerative diseases are associated with increased oxidative stress and apoptosis in neuronal tissue.
Schindowski, Katharina +4 more
core
Retrospective Grid Cells in the Medial Entorhinal Cortex Encode Past Paths During Spatial Navigation
Advanced Science, EarlyView.Retrospective grid cells are identified in the medial entorhinal cortex, with spatial firing patterns that become most grid‐like when activity is projected onto recently traversed locations. Their coding loses spatial precision in darkness and is disrupted during assisted movement, indicating that entorhinal representations incorporate recent path ...
Ruojin Liu +10 more
wiley +1 more source
Iraqi Journal of Pharmaceutical Sciences, 2021 The present study evaluates the effects of Ginkgo biloba extract as monotherapy on the glycemic status, insulin resistance (IR), body mass index (BMI), and visceral adiposity index (VAI), in addition to the inflammatory markers, oxidative status and ...
Tavga A. Aziz
doaj +1 more source
Efficacy and safety of a Ginkgo biloba extract [PDF]
Public Health Nutrition, 2000 AbstractThis review of the literature documents the efficacy of a standard extract of Ginkgo biloba (EGb) in managing signs and symptoms associated with memory disorders and dementia. Analysis of the discrepant findings reveals that study outcomes may vary with the type of population studied, the outcome measurements selected, and the dosing tested ...
P L, Le Bars, J, Kastelan
openaire +2 more sources
Large‐Scale Machine Learning to Screen for Small‐Molecule Senolytics
Advanced Intelligent Discovery, EarlyView.A consistent workflow underpins all experiments in this study. A dedicated model‐selection dataset first identifies optimal hyperparameters for each algorithm. Models are then trained and rigorously evaluated on independent sets of molecules using the senolytic ratio SR. Comprehensive hyperparameter exploration across SMILES representations, task types,
Alexis Dougha +2 more
wiley +1 more source
Ginkgo Biloba Extract Enhances Male Copulatory Behavior and Reduces Serum Prolactin Levels in Rats
, 2009 The aim of this study was to investigate the effects of Ginkgo biloba extract (EGb 76 1) on male copulatory behavior in rats. EGb 761 (1 mg/ml) induced significant production of testosterone (T) in rat Leydig cells in vitro.
YEH, KUEI-YING;PU, HSIAO-FUNG;LIN, SHIH -FAN;WU, LEANG-SHIN;LIN, JEN-HSOU;TSAI, YUAN-FEEN +1 more
core +1 more source
Animal Research and One Health, EarlyView.Dietary A. truncatum leaf extract is absorbed and improves laying performance in aged hens by enhancing systemic antioxidant capacity and modulating the gut microbiota. ABSTRACT The demand for natural feed additives is considerably increasing in the antibiotic‐free feed era.
Kailong Qin +6 more
wiley +1 more source
Ginkgo biloba extract inhibits the proliferation and migration of human glioma cell line U87 [PDF]
Jichu yixue yu linchuangObjective To find potential effect of Ginkgo biloba extract on proliferation and migration of human glioma cell line. Methods Glioma cell line U87 was cultured and incubated with Ginkgo biloba extract at doses of 0, 10, 50, and 100 μg/mL, respectively ...
MA Yue, HUANG Conggang, WANG Yuan, XU Wenqing, LUO Zhihua
doaj +1 more source