Results 11 to 20 of about 30,545 (193)

Panax ginseng improves physical recovery and energy utilization on chronic fatigue in rats through the PI3K/AKT/mTOR signalling pathway

Pharmaceutical Biology, 2023
Context Panax ginseng C. A. Meyer (Araliaceae) is a tonic herb used in ancient Asia.Objective This study investigated the antifatigue effect of P. ginseng on chronic fatigue rats.Materials and methods Sprague-Dawley rats were divided into control, model ...
Guolei Zhang, BoFan Lu, Enhui Wang, Wei Wang, Zheng Li, Lili Jiao, Hui Li, Wei Wu   +7 more
doaj   +1 more source

Study of the Mechanism of Astragali Radix in Treating Type 2 Diabetes Mellitus and Its Renal Protection Based on Enzyme Activity, Network Pharmacology, and Experimental Verification

Molecules, 2023
Astragali Radix (AR) is a common Chinese medicine and food. This article aims to reveal the active role of AR in treating Type 2 diabetes mellitus (T2DM) and its renal protective mechanism.
Chunnan Li, Kaiyue Zhang, Lu Liu, Jiaming Shen, Yuelong Wang, Yiying Tan, Xueqin Feng, Wanjie Liu, Hui Zhang, Jiaming Sun   +9 more
doaj   +1 more source

Ginsenoside Rh2 represses autophagy to promote cervical cancer cell apoptosis during starvation

Chinese Medicine, 2020
Background Cancer cells through autophagy-mediated recycling to meet the metabolic demands of growth and proliferation. The steroidal saponin 20(S)-ginsenoside Rh2 effectively inhibits the growth and survival of a variety of tumor cell lines and animal ...
Jiawen Wang, Shuai Bian, Siming Wang, Song Yang, Wanying Zhang, Daqing Zhao, Meichen Liu, Xueyuan Bai   +7 more
doaj   +1 more source

Comprehensive RNA sequencing in primary murine keratinocytes and fibroblasts identifies novel biomarkers and provides potential therapeutic targets for skin-related diseases

Cellular & Molecular Biology Letters, 2021
Background Keratinocytes and fibroblasts represent the major cell types in the epidermis and dermis of the skin and play a significant role in maintenance of skin homeostasis.
Tiancheng Wang, Zhenwei Zhou, Enjing Luo, Jinghong Zhong, Daqing Zhao, Haisi Dong, Baojin Yao   +6 more
doaj   +1 more source

First Report of Sclerotinia Rot Caused by Sclerotinia nivalis on Panax ginseng in Korea

Research in Plant Disease, 2013
Sclerotinia rot disease was observed on 5 and 6-year-old ginseng (Panax ginseng) roots in Hongchun, Cheorwon, and Yanggu, Gangwon Province, Korea from 2006 to 2010. Symptoms included a brownish watery soft rot of the roots, and black sclerotia were often
Hye Sun Cho, Jeong-Sup Shin, Jae-Hyun Kim, Tae-Kyun Hong, Dae-Hui Cho , Je Yong Kang   +5 more
doaj   +1 more source

Cloning and characterization of thermophilic endoglucanase and its application in the transformation of ginsenosides

AMB Express, 2022
A novel endoglucanase (BcelFp) was identified from Fervidobaterium pennivorans DSM9078 which had biotransformation activity for protopanaxadiol (PPD)-type ginsenosides.
Fei Zheng, Huanxi Zhao, Nan Wang, Peng Zhong, Kailu Zhou, Shanshan Yu   +5 more
doaj   +1 more source

Evaluation and Screening of Hypoglycemic Activity of Total Ginsenosides GBE-5 Fraction From Panax Ginseng Berry Based on UHPLC–MS Metabolomics

Frontiers in Nutrition, 2022
ObjectiveGinseng berry (GB) was the mature fruit of medicinal and edible herb, Panax ginseng C.A. Meyer, with significant hypoglycemic effect. Ginsenoside was the main hypoglycemic active component of GB. Evaluating and screening the effective components
Heyu Wang, Heyu Wang, Yu Tong, Anqi Wang, Ying Li, Bofan Lu, Hui Li, Lili Jiao, Wei Wu   +8 more
doaj   +1 more source

The anti-aging effect of velvet antler polypeptide is dependent on modulation of the gut microbiota and regulation of the PPAR𝜶/APOE4 pathway [PDF]

Journal of Integrative Neuroscience, 2021
We investigated the anti-aging effects of velvet antler polypeptide on D-galactose (D-gal)-induced aging mice. D-gal-induced aging mice were established and randomly divided into five groups, the control, model, vitamin E (VE), velvet antler ...
Xiaoran Liu, Qing Yang, Hui Li, Xingcheng Lan, Mo Kan, Jianan Lin, Jifeng Wang, Zhuang Zhang, Sitong Ming, Zhen Li, Yaxin Liu, Yanhong Zhang, Qihang Pang, Song Gao, Na Li   +14 more
doaj   +1 more source

Metabolomic approach for discrimination of processed ginseng genus (Panax ginseng and Panax quinquefolius) using UPLC-QTOF MS

Journal of Ginseng Research, 2014
Discriminating between two herbal medicines (Panax ginseng and Panax quinquefolius), with similar chemical and physical properties but different therapeutic effects, is a very serious and difficult problem.
Hee-Won Park, Gyo In, Jeong-Han Kim, Byung-Goo Cho, Gyeong-Ho Han, Il-Moo Chang   +5 more
doaj   +1 more source

Carbon nanodots constructed by ginsenosides and their high inhibitory effect on neuroblastoma

Journal of Nanobiotechnology, 2023
Background Neuroblastoma is one of the common extracranial tumors in children (infants to 2 years), accounting for 8 ~ 10% of all malignant tumors. Few special drugs have been used for clinical treatment currently.
Yingnan Jiang, Lizhi Xiao, Jifeng Wang, Tenghui Tian, Guancheng Liu, Yu Zhao, Jiajuan Guo, Wei Zhang, Jiawen Wang, Changbao Chen, Wenyi Gao, Bai Yang   +11 more
doaj   +1 more source