Results 131 to 140 of about 5,453 (156)

Methanol-involved heterogeneous transformation of ginsenoside Rb1 to rare ginsenosides using heteropolyacids embedded in mesoporous silica with HPLC-MS investigation. [PDF]

J Ginseng Res
Zhao M, Xiao Y, Chang Y, Tian L, Zhou Y, Liu S, Zhao H, Xiu Y.   +7 more
europepmc   +1 more source

Ginsenoside Rb1 induces hepatic stellate cell ferroptosis to alleviate liver fibrosis via the BECN1/SLC7A11 axis. [PDF]

J Pharm Anal
Lin L, Li X, Li Y, Lang Z, Li Y, Zheng J.   +5 more
europepmc   +1 more source

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Ginsenoside Rb1 Suppresses AOM/DSS-induced Colon Carcinogenesis

Anti-Cancer Agents in Medicinal Chemistry, 2023
Background: Colorectal cancer (CRC) is the third most common cancer worldwide. Current treatments, including surgery, radiotherapy, and chemotherapy, are limited by severe side effects and the development of resistance. Objective: Therefore, it is important to find additional therapies to combat the problem.
Ling, Wang, Qing-Qing, Zhang, Yu-Yu, Xu, Rui, Zhang, Qing, Zhao, Yu-Qing, Zhang, Xue-Hong, Huang, Bin, Jiang, Min, Ni   +8 more
openaire   +2 more sources

Isolation of ginsenoside Rb1 fromKalopanax pictus by eastern blotting using anti-ginsenoside Rb1 monoclonal antibody

Phytotherapy Research, 2005
Araliaceous species containing ginsenosides, the major active component in Panax species, were surveyed using ELISA and eastern blotting with anti-ginsenoside Rb1 monoclonal antibody. Immunoassay-guided fractionation of the methanol-soluble extracts of Araliaceous species led to the isolation of a known compound in the bark of Kalopanax pictus Nakai ...
Hiroyuki, Tanaka, Noriko, Fukuda, Shoji, Yahara, Susumu, Isoda, Chun-Su, Yuan, Yukihiro, Shoyama   +5 more
openaire   +2 more sources

Conversion of Major Ginsenoside Rb1 to Ginsenoside F2 by Caulobacter leidyia

Biotechnology Letters, 2006
Ginsenoside Rb1 is the most predominant ginsenoside in Panax species (ginseng) and the hydrolysis of this ginsenoside produces pharmaceutically active compounds. Caulobacter leidyia GP45, one of the isolates having strong beta-glucosidase-producing activity, converted ginsenoside Rb(1) to the active metabolites by 91%.
Le-Qin, Cheng, Myung Kyum, Kim, Jun-Won, Lee, Youn-Jin, Lee, Deok-Chun, Yang   +4 more
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Ginsenoside Rb1 and Rg3 Attenuate Glucocorticoid-Induced Neurotoxicity

Cellular and Molecular Neurobiology, 2010
Glucocorticoid (GC) hormones, increased in response to stress, can cause neuronal loss. We tested the effect of GC hormone on cell viability of neural SHSY-5Y cells and protective effects of ginsenoside Rb1 and Rg3 on the action of GC. We treated SHSY-5Y cells with increasing concentrations of synthetic GC dexamethasone (DEX; 10, 25, 50, and 100 nM ...
Sung-Ok, Kim, Jung-Man, You, Su-Jin, Yun, Min-Sook, Son, Kyong Nyon, Nam, Joung-Woo, Hong, Sun Yeou, Kim, Sang Yoon, Choi, Eunjoo H, Lee   +8 more
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Biotransformation of Ginsenoside Rb1 to Ginsenoside CK by Strain XD101: a Safe Bioconversion Strategy

Applied Biochemistry and Biotechnology, 2021
Ginsenoside Rb1 is the main predominant component in Panax species. In this study, an eco-friendly and convenient preparation method for ginsenoside CK has been established, and five strains of β-glucosidase-producing microorganisms were screened out from the soil of a Panax notoginseng planting field using Esculin-R2A agar.
Yunyun Jiang, Weina Li, Daidi Fan
openaire   +2 more sources

Pharmacokinetic Study of Ginsenosides Rb1 and Rg1 in Rat by ELISA Using Anti-ginsenosides Rb1 and Rg1 Monoclonal Antibodies

The American Journal of Chinese Medicine, 2006
Enzyme-linked immunosorbent assay (ELISA) systems using anti-ginsenoside Rb1 (G-Rb1) and Rg1 (G-Rg1) monoclonal antibodies (MAbs) were established for pharmacokinetic investigations of G-Rb1 and G-Rg1 in rat serum. The systems not only allowed sensitive detection of G-Rb1 at the level as low as 20 ng/ml and of G-Rg1 at 300 ng/ml, but showed strong ...
Zhi, Chao, Yukihiro, Shoyama, Hiroyuki, Tanaka   +2 more
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Ginsenoside Rb1 blocks Homocysteine-induced endothelial dysfunction

Journal of Surgical Research, 2004
Abstract Background. Homocysteine (HCY) is an independent risk factor for atherosclerosis. This study is to investigate the effect of ginsenoside Rb1, a major constituent of ginseng, on HCY-induced endothelial dysfunction and molecular changes in porcine coronary arteries. Methods.
W. Zhou, H. Chai, P. Lin, A.B. Lumsden, C. Chen, C. Chen   +5 more
openaire   +1 more source