Results 91 to 100 of about 9,296 (235)

Protective Effects of Ginsenoside Rg1 on Acute Myocardial Infarction

Journal of Pharmacy and Pharmacology Research, 2020
Context: Ginsenoside Rg1 (Rg1), as the active ingredient of Panax notoginseng, has protective effect on the cardiovascular system. While, the efficiency of Rg1 against acute myocardial infarction (MI) is not fully elucidated. The aim of this study was to investigate the cardio-protection and the underlying mechanism for Rg1.
Xiaoyu Wang, Linlin Wang, Lili Qi, Huimiao Bian, Xing Yan, Yan Wang, Xiaodong Li, Kenka Cho, Guojiang Wu, Baohong Jiang   +9 more
openaire   +1 more source

Neuroprotective Effects of Ginsenoside Rg3 in Depressed Mice via Inhibition of the C1q Complement Pathway

CNS Neuroscience &Therapeutics, Volume 31, Issue 11, November 2025.
Complement factors mediate microglial activation and their phagocytic function in a chronic inflammatory environment. Ginsenoside Rg3 may reduce complement factor secretion and inhibit neuronal apoptosis by regulating microglial activation, thereby exerting a protective effect on neurons.
Daofeng Yang, Xinran Xu, Xuerui Zhuo, Hui Cai, HaoTian Wang, Hao Liu, Yiming Sun   +6 more
wiley   +1 more source

Ginsenoside Rg1 alleviates chronic testicular damage caused by cranial irradiation through the SCF/PI3K/Akt/mTOR pathway in mice

Radiation Medicine and Protection
Objective: To investigate whether Ginsenoside Rg1 can mitigate the adverse effects of cranial irradiation on distal reproductive function in mice and to explore the underlying mechanisms.
Qiuhua Zhou, Yiquan Ou, Xiangsheng Tian, Yujun Ning, Yuwei Mao, Weichao Zhao, Dingxin Long   +6 more
doaj   +1 more source

Ginsenoside Rg1 Inhibits High Glucose-Induced Proliferation, Migration, and Angiogenesis in Retinal Endothelial Cells by Regulating the lncRNA SNHG7/miR-2116-5p/SIRT3 Axis [PDF]

, 2022
Liping Xue, Min Hu, Juanjuan Li, Yadi Li, Qin Zhu, Guanglong Zhou, Xiaofan Zhang, Yuan Zhou, Jieying Zhang, Peng Ding   +9 more
openalex   +1 more source

Recent Advances in Injectable Hydrogel Biotherapeutics for Regenerative Dental Medicine

Macromolecular Bioscience, Volume 25, Issue 10, October 2025.
This review analyses multifunctional injectable hydrogels, natural or synthetic, physically or chemically crosslinked, that deliver exosomes, stem cells, and other bioactive cues to inflamed or damaged oral tissues. We discuss their immunomodulatory, antimicrobial, angiogenic, and osteogenic capacities, highlighting advances that enable regenerative ...
Renan Dal‐Fabbro, Arwa Daghrery, Caroline Anselmi, Igor Paulino M. Soares, Alexandre Henrique dos Reis‐Prado, Pedro Henrique Chaves de Oliveira, Marco C. Bottino   +6 more
wiley   +1 more source

Antidepressant-like Effects of Ginsenoside Rg1 in the Chronic Restraint Stress-induced Rat Model

Digital Chinese Medicine, 2019
Objective: To investigate the ameliorating effect of ginsenoside Rg1 on the depression-like behaviors induced by chronic restraint stress (CRS) in rats and the underlying mechanisms. Methods: Forty male Wistar rats were divided into 4 groups according to
Jiang Ning, Lv Jing-Wei, Wang Hai-Xia, Huang Hong, Wang Qiong, Chen Shan-Guang, Qu Li-Na, Alberto Carlos Pires Dias, Liu Xin-Min   +8 more
doaj   +1 more source

American Ginseng Modifies 137Cs-Induced DNA Damage and Oxidative Stress in Human Lymphocytes [PDF]

, 2009
The multifold bioactive medicinal properties of ginseng have been closely linked to its antioxidative ability, which is related to its ginsenoside content.
Allison, Ron R., Johnke, Roberta M., Lee, Tung-Kwang, O'Brien, Kevin F., Sheng, Chao, Wang, Tao, Wang, Weidong   +6 more
core   +1 more source

Single‐cell sequencing and mass spectrometry imaging reveal the multicellular compartmentalization map of plant triterpenes: A ginsenoside in Panax ginseng example

Plant Biotechnology Journal, Volume 23, Issue 10, Page 4461-4476, October 2025.
Summary Revealing the multicellular compartmentalization map is crucial for plant breeding and metabolism regulation. Despite the importance of triterpenes as active compounds, there has been no report on their biosynthetic multicellular mapping. In this study, ginsenosides are used as an example to reveal the multicellular compartmentalization map of ...
Rubing Wang, Luyao Zhang, Xia Li, Wensong Sun, Yike Wang, Luqi Huang, Juan Wang, Wenyuan Gao, Lanping Guo   +8 more
wiley   +1 more source

Characterization of Chondrogenic Gene Expression and Cartilage Phenotype Differentiation in Human Breast Adipose-Derived Stem Cells Promoted by Ginsenoside Rg1 In Vitro

Cellular Physiology and Biochemistry, 2015
Background/Aims: Investigating and understanding chondrogenic gene expression during the differentiation of human breast adipose-derived stem cells (HBASCs) into chondrogenic cells is a prerequisite for the application of this approach for cartilage ...
Fang-Tian Xu, Hong-Mian Li, Cheng-Yi Zhao, Zhi-Jie Liang, Min-Hong Huang, Qing Li, Ying-Chao Chen, Gang-Yi Chi   +7 more
doaj   +1 more source

Radioprotective Effect of American Ginseng on Human Lymphocytes at 90 Minutes Post-irradiation: A Study of 40 Cases [PDF]

, 2010
Backgroundâ Ionizing radiation (IR) initiates intracellular oxidative stress through enhanced formation of reactive oxygen species (ROS) that attack DNA leading to cell death. As the diversity of IR applied in medicine, agriculture, industry, and the
Chao Sheng, Grdina DJ, Kevin F. O'Brien, Kitts DD, Roberta M. Johnke, Ron R. Allison, Sidi M. Benhabib, SPSS, Tao Wang, Tung-Kwang Lee, Weidong Wang   +10 more
core   +3 more sources