Results 81 to 90 of about 6,031 (176)

Mass Production of Rg1-Loaded Small Extracellular Vesicles Using a 3D Bioreactor System for Enhanced Cardioprotective Efficacy of Doxorubicin-Induced Cardiotoxicity

Pharmaceutics
Background: Small extracellular vesicles (sEVs) obtained from human umbilical cord mesenchymal stromal cells (MSCs) have shown cardioprotective efficacy in doxorubicin-induced cardiotoxicity (DIC).
Yunfeng Di, Shuang Zhao, Huilan Fan, Wei Li, Guangjian Jiang, Yong Wang, Chun Li, Wei Wang, Jingyu Wang   +8 more
doaj   +1 more source

Ginsenoside Rg1: A bioactive therapeutic agent for diverse liver diseases

Pharmacological Research
Diverse liver diseases are characterised by late diagnosis and rapid progression and have become one of the major threats to human health. To delay the transition from benign tissue lesions to a substantial organ injury, scientists have gradually applied natural compounds derived from plants as a complementary therapy in the field of hepatology ...
Mingyu Wu, Ke Li, Jiabin Wu, Xianyi Ding, Xiaotong Ma, Wenhong Wang, Weihua Xiao   +6 more
openaire   +3 more sources

Ginsenoside Rg1 exerts anti-arrhythmic effect by inhibiting I through cAMP-PKA and PI3K-AKT signaling pathways in rat ventricular myocytes after myocardial ischemia-reperfusion injury

Science Progress
Objective Ginsenoside Rg1 has demonstrated beneficial effects in myocardial ischemia-reperfusion (I/R) injury. However, its potential anti-arrhythmic role in ventricular arrhythmias remains unclear.
Teng Wang, Hongyi Zhao, Yuting Chen, Sheng Guo, Chengzhi Zhou, Hong Cao, Qiang Zou, Qingxiu Wang   +7 more
doaj   +1 more source

Protective role of ginsenoside Rg1 in the dynamic progression of liver injury to fibrosis: a preclinical meta-analysis

Frontiers in Pharmacology
BackgroundThe pathological progression from liver injury to fibrosis is a hallmark of liver disease, with no effective strategies to halt this transition.
Lijuan Dan, Xiuyan Li, Shuanglan Chen, Xiaojie You, Dong Wang, Tianyuan Wang, Jia Li, Wenping Liu, Jie Mu, Quansheng Feng, Quansheng Feng   +10 more
doaj   +1 more source

Spiral cone fiber SPR sensor for detecting ginsenoside Rg1

Optics Express
The conical fiber SPR sensor is easy to manufacture and has been used in biochemical detection research, but it has the problem of structural fragility. This article proposes a spiral cone fiber SPR sensor, which introduces a spiral structure on the 76µm fiber coarse cone, achieving good coupling of the core mode into the cladding mode, and improving ...
Yong Wei, Chengling Shi, Yonghui Zhang, Chunlan Liu, Chunbiao Liu, Chen Shi, Xingkai Wang, Yixiong Tang, Ziqiang Zhang, Zhihai Liu   +9 more
openaire   +2 more sources

Ginsenoside Rg1 alleviates vascular remodeling in hypoxia-induced pulmonary hypertension mice through the calpain-1/STAT3 signaling pathway

Journal of Ginseng Research
Background: Hypoxic pulmonary hypertension (HPH) is the main pathological change in vascular remodeling, a complex cardiopulmonary disease caused by hypoxia. Some research results have shown that ginsenoside Rg1 (Rg1) can improve vascular remodeling, but
Chenyang Ran, Meili Lu, Fang Zhao, Yi Hao, Xinyu Guo, Yunhan Li, Yuhong Su, Hongxin Wang   +7 more
doaj   +1 more source

Ginsenoside Rg1 ameliorates cardiac oxidative stress and inflammation in streptozotocin-induced diabetic rats

Diabetes, Metabolic Syndrome and Obesity, 2019
Qiaoji Qin, Nan Lin, Huan Huang, Xuezhi Zhang, Xuelei Cao, Yongbin Wang, Peng LiEmergency Department, The Affiliated Hospital of Qingdao University, Qingdao 266003, Shandong, People’s Republic of ChinaBackground and purpose: Ginsenoside Rg1 (GS Rg1)
Qin Q, Lin N, Huang H, Zhang X, Cao X, Wang Y, Li P   +6 more
doaj  

Ginsenoside Rg1 triggers ferroptosis to inhibit hepatocellular carcinoma via SLC7A11 downregulation. [PDF]

Discov Oncol
Wei A, Liu Z, Zhao F, Zhao Y, Liu B.
europepmc   +1 more source

Ginsenoside Rg1 Alleviates Lead-Induced Neurotoxicity Through Nrf2-Associated Modulation of Oxidative Stress and Ferroptosis. [PDF]

Molecules
Gong Y, Zhang J, Wang T, Li X, Wang H, Ren L.   +5 more
europepmc   +1 more source

Anti-Inflammatory Effects of Ginsenoside Rg1 and Low-Dose Ginseng Extract in an Astrocyte-Microglia Co-Culture Model of Inflammation. [PDF]

Pharmaceutics
An S, Schönfelder L, Reusch P, Faustmann PM, Ismail FS, Faustmann TJ.   +5 more
europepmc   +1 more source