Results 91 to 100 of about 6,513 (215)

Ginsenoside Rg1 promotes remyelination and functional recovery in demyelinating disease by enhancing oligodendrocyte precursor cells-mediated myelin repair.

Phytomedicine, 2022
BACKGROUND Inefficient differentiation of oligodendrocyte precursor cells (OPCs) is one of the significant pathological obstacles of myelin repair and provides an essential therapeutic target against behavioral dysfunction in various neurodegenerative ...
Li Liu, Xinke Du, Qing Yang, Manjing Li, Q. Ran, Qingwu Liu, Lina Yang, Lisong Sun, Yuxuan Guo, Yujie Li, Ying Chen, Xiaoxin Zhu, Qi Li   +12 more
semanticscholar   +1 more source

Encephalopathy: Cause, Pathogenesis, and Treatment

MedComm, Volume 7, Issue 6, June 2026.
Various encephalopathies (sepsis‐associated, hepatic, hypoxic–ischemic, diabetic, uremic, toxic) have incompletely elucidated pathogenesis, which severely restricts targeted therapy development. Small molecule drugs show unique multitarget potential but face toxicity, poor blood–brain barrier penetration and unclear specificity.
Shimeng Lv, Xia Zhong, Ruirui Shang, Linghui Kong, Yufei Huang, Yuexiang Ma, Jing Teng, Sheng Wei   +7 more
wiley   +1 more source

Chromosome‐Level Genome Assembly of the Allotetraploid Gynostemma pentaphyllum Provides Novel Insights Into the Biosynthesis of Ginsenoside and Gypenoside LVI

Plant Biotechnology Journal, Volume 24, Issue 6, Page 4204-4220, June 2026.
ABSTRACT Gynostemma pentaphyllum, a herb used in tea and traditional Chinese medicine, shows geographic variation in its production of valuable dammarane‐type ginsenosides and gypenoside LVI between populations from Suining (SN) and Nanning (NN). To elucidate the mechanisms underlying this differential metabolite accumulation, a chromosome‐level genome
Peina Zhou, Si‐Jie Liu, Lijin Huang, Yingping Wang, Xinyu Jiang, Wang Dong, Jianfeng Gong, Long Wang, Yuyin Zhao, Huiying Wang, Ping Li, Jia‐Yu Xue, Xu Lu   +12 more
wiley   +1 more source

Regulated Cell Death in Idiopathic Pulmonary Fibrosis

The FASEB Journal, Volume 40, Issue 9, 15 May 2026.
This graphical abstract illustrates regulated cell death (RCD) across key pulmonary cell types—including alveolar epithelial cells, fibroblasts, macrophages, and endothelial cells—modulated through a dynamic death modulation network within the IPF microenvironment.
Xiaoyue Pan, Liu Yang, Man Zhao, Yanlin Zhou, Cong Xia, Huibing Liu, Yuqi Wang, Hui Lian, Bin Li, Lan Wang, Guoying Yu   +10 more
wiley   +1 more source

Component Analysis of Cultivated Ginseng, Red Ginseng, Cultivated Wild Ginseng, and Red Wild Ginseng Using HPLC Method

Journal of Pharmacopuncture, 2008
Objectives : The aim of this experiment is to provide an differentiation of ginseng, red ginseng, cultivated wild ginseng(CWG), and red wild ginseng(RWG) through component analysis using HPLC(High Performance Liquid Chromatography, hereafter HPLC ...
Jang Ho, Lee, Ki Rok, Kwon, Bae Chun, Cha   +2 more
doaj   +1 more source

Emerging Role of Panax ginseng in the Management of Cancer: Phytochemistry, SAR, Therapeutic Potential, and Clinical Aspects

Food Frontiers, Volume 7, Issue 3, May 2026.
This review aims to provide a comprehensive understanding of the therapeutic potential of bioactive anticancer phytoconstituents in Panax ginseng, including their clinical aspects and SAR, thereby fostering the development of newer anticancer compounds for cancer management.
Akrit Verma, Sanjeev Kumar Sahu, Anil Kumar Sah   +2 more
wiley   +1 more source

Liver Fibrosis: Molecular Pathogenesis and Therapeutic Interventions

MedComm, Volume 7, Issue 5, May 2026.
We systematically summarized the etiologies, diagnostic approaches, and pathogenic mechanisms of liver fibrosis. Also, the therapeutic interventions for liver fibrosis were systematically classified into two main categories: etiological treatment and mechanism‐based antifibrotic therapies.
Jiaorong Qu, Wenqing Qin, Minghang Dong, Zhi Ma, Si Li, Runping Liu, Ranyun Chen, Changmeng Li, Xiaojiaoyang Li   +8 more
wiley   +1 more source

Injectable Liposome‐Anchored Hydrogel Microspheres Promote Spinal Cord Injury Repair by Modulating the Inflammatory Microenvironment and Recruiting Endogenous Stem Cells

Small Structures, Volume 7, Issue 4, April 2026.
This study presents R‐L@S‐GMs, an injectable liposome‐anchored hydrogel microsphere system for spinal cord injury repair. The platform utilizes the sequential release of Rg1 and SDF1α to modulate inflammation and recruit endogenous stem cells. By transforming the inhibitory microenvironment, this innovative composite promotes neuronal regeneration and ...
Hao Wang, Wenjun Zou, Kelv Shen, Yin Zhu, Baihan Sun, Feiyun Xia, Zeyu Han, Zhengfeng Lu   +7 more
wiley   +1 more source

Contrasting actions of ginsenosides Rb1 and Rg1 on glucose tolerance in rats

Chinese Journal of Physiology, 2019
Ginsenoside profile of Panax ginseng is changing with season and cultivated soil. Yet, dose-response relationship of main ginsenosides on metabolic measures has not been documented in vivo. Here, we examined glucose and insulin responses after an oral glucose challenge (0.5 g/kg body weight) at various doses (0.01, 0.1, 1, and 10 mg/kg of body weight ...
Rungchai Chaunchaiyakul, Naruemon Leelayuwat, Jin-Fu Wu, Chih-Yang Huang, Chia-Hua Kuo   +4 more
openaire   +3 more sources

Ginsenoside Rg1 alleviates chronic testicular damage caused by cranial irradiation through the SCF/PI3K/Akt/mTOR pathway in mice

Radiation Medicine and Protection
Objective: To investigate whether Ginsenoside Rg1 can mitigate the adverse effects of cranial irradiation on distal reproductive function in mice and to explore the underlying mechanisms.
Qiuhua Zhou, Yiquan Ou, Xiangsheng Tian, Yujun Ning, Yuwei Mao, Weichao Zhao, Dingxin Long   +6 more
doaj   +1 more source