Results 71 to 80 of about 6,513 (215)

Radioimmunoassay for the determination of ginseng saponin, ginsenoside RG1.

open access: yesChemical and Pharmaceutical Bulletin, 1982
Radioimmunoassay method for the determination of ginsenoside Rg1, one of the major saponins of Panax ginseng root, was established. The side chain of ginsenoside Rg1 was modified and coupled to BSA. 125I-Labelled compound of ginsenoside Rg1 was prepared from a ginsenoside Rg1-tyramine conjugate.
Sankawa, Ushio   +4 more
openaire   +2 more sources

Ginsenoside Rg1 ameliorates apoptosis, senescence and oxidative stress in ox-LDL-induced vascular endothelial cells via the AMPK/SIRT3/p53 signaling pathway

open access: yesExperimental and Therapeutic Medicine, 2022
Coronary heart disease (CHD) mainly refers to coronary atherosclerotic heart disease and its pathogenesis is complex. Ginsenoside Rg1 (Rg1) has a wide range of pharmacological activities, such as antitumor effects, enhancing immunity and exerting ...
Tian-Jiao Lyu   +3 more
semanticscholar   +1 more source

Ginsenoside Rg1 Improves -produced Embryo Quality by Increasing Glucose Uptake in Porcine Blastocysts [PDF]

open access: yesAsian-Australasian Journal of Animal Sciences, 2016
Ginsenoside Rg1 is a natural compound with various efficacies and functions. It has beneficial effects on aging, diabetes, and immunity, as well as antioxidant and proliferative functions. However, its effect on porcine embryo development remains unknown.
Seung-Hun Kim   +6 more
doaj   +1 more source

Advances in the Neurotoxic Mechanisms of Acrylamide and Multitarget Intervention Strategies of Natural Products

open access: yesFood Frontiers, Volume 7, Issue 4, July 2026.
This review summarizes recent advances in acrylamide neurotoxicity mechanisms and highlights the multitarget neuroprotective effects of diverse natural products while also addressing current challenges and future translational research directions.
Wen Du   +7 more
wiley   +1 more source

Ginsenoside Rg1 alleviates acute liver injury through the induction of autophagy and suppressing NF-κB/NLRP3 inflammasome signaling pathway

open access: yesInternational Journal of Medical Sciences, 2021
Background: Severe hepatitis is a common cause of chronic or acute liver disease and autophagy might play an important role in cellular response to inflammation and injury.
Jinqiu Zhao   +4 more
semanticscholar   +1 more source

Ginsenoside Rg1 inhibits dietary-induced obesity and improves obesity-related glucose metabolic disorders

open access: yesBrazilian Journal of Medical and Biological Research, 2018
Obesity and its consequent type 2 diabetes are significant threats to global health. Emerging evidence indicates that ginsenosides from ginseng (Panax ginseng) have anti-diabetic activity.
Jin-bo Li   +3 more
doaj   +1 more source

Urologic Bacteriome: The Hero or the Villain in Prostate Cancer Onset, Progression, and Treatment?

open access: yesMedicinal Research Reviews, Volume 46, Issue 4, Page 1111-1151, July 2026.
ABSTRACT Prostate cancer (PCa) is the second most frequently diagnosed cancer in men worldwide and the fifth leading cause of cancer‐related mortality, presenting urgent unmet clinical needs in diagnosis and treatment. The recognition of the microbiome as a key factor in human health has prompted numerous studies, revealing an exciting new approach to ...
Lara R. S. Fonseca   +6 more
wiley   +1 more source

Ginsenoside Rg1 promotes endothelial progenitor cell migration and proliferation [PDF]

open access: yesActa Pharmacologica Sinica, 2009
To investigate the effect of ginsenoside Rg1 on the migration, adhesion, proliferation, and VEGF expression of endothelial progenitor cells (EPCs).EPCs were isolated from human peripheral blood and incubated with different concentrations of ginsenoside Rg1 (0.1, 0.5, 1.0, and 5.0 micromol/L) and vehicle controls.
Ai-wu, Shi   +5 more
openaire   +2 more sources

Ginsenoside Rg1 Ameliorates Neuroinflammation via Suppression of Connexin43 Ubiquitination to Attenuate Depression

open access: yesFrontiers in Pharmacology, 2021
Depression is an inflammation-associated disease that results in major depression as inflammation increases and progresses. Ginsenoside Rg1 (Rg1), the major bioactive ingredient derived from ginseng, possesses remarkable anti-depressant and anti ...
Huiqin Wang   +7 more
semanticscholar   +1 more source

Ginsenoside Rg1 Prevents Chronic Stress-Induced Depression-Like Behaviors and Neuronal Structural Plasticity in Rats

open access: yesCellular Physiology and Biochemistry, 2018
Background/Aims: Ginsenoside Rg1 has been demonstrated to exhibit neuroprotective effects in various studies. This study aimed to investigate the neuronal mechanisms underlying the neuroprotective and antidepressant-like effects of ginsenoside Rg1 in a ...
Hongluan Yu   +6 more
doaj   +1 more source

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