Results 71 to 80 of about 8,086 (216)

Ginsenoside Rg1 Improves Differentiation by Inhibiting Senescence of Human Bone Marrow Mesenchymal Stem Cell via GSK-3β and β-Catenin

open access: yesStem Cells International, 2020
Objectives. To demonstrate the effect of Ginsenoside Rg1 on the differentiation of human bone marrow-derived mesenchymal stem cells (hBM-MSCs).
Ziling Wang   +8 more
doaj   +1 more source

Screening and Evaluation of Anti-aging Activity of Ginsenosides Based on Saccharomyces cerevisiae System

open access: yesShipin gongye ke-ji, 2022
Saccharomyces cerevisiae was used as a model organism to screen the anti-aging activity of ginsenosides and explore its activities. The optimal concentration of ginsenoside was screened out based on the growth curve of the model strain Saccharomyces ...
Jingjing CHEN   +4 more
doaj   +1 more source

Injectable Liposome‐Anchored Hydrogel Microspheres Promote Spinal Cord Injury Repair by Modulating the Inflammatory Microenvironment and Recruiting Endogenous Stem Cells

open access: yesSmall Structures, Volume 7, Issue 4, April 2026.
This study presents R‐L@S‐GMs, an injectable liposome‐anchored hydrogel microsphere system for spinal cord injury repair. The platform utilizes the sequential release of Rg1 and SDF1α to modulate inflammation and recruit endogenous stem cells. By transforming the inhibitory microenvironment, this innovative composite promotes neuronal regeneration and ...
Hao Wang   +7 more
wiley   +1 more source

Targeting Autophagy in Ovarian Cancer: The Emerging Role of Ginsenosides

open access: yesCancer Medicine, Volume 15, Issue 3, March 2026.
ABSTRACT Background Ovarian cancer, the third most prevalent gynecological malignancy, is frequently diagnosed at an advanced stage owing to its asymptomatic early progression. Despite the application of conventional therapies, clinical management remains limited by adverse effects and the development of drug resistance.
Yuxin Guo   +4 more
wiley   +1 more source

A review study on medicinal plants affecting amnesia through cholinergic system [PDF]

open access: yes, 2012
Neurotransmitter modification is an important method for the treatment of memory loss or amnesia. Cholinomimetic drugs, particularly, acetylcholine esterase inhibitors are the mainstream in pharmacotherapy of amnesia. Donepezil, tacrine, galantamine, and
Baradaran, Azar.   +3 more
core  

Drug wastage among the elderly living in old aged homes in Hong Kong [PDF]

open access: yes, 2013
The extend of drug wastage among elderly living in old aged homes was never investigated. Upon the completion of the previous study on pharmaceutical services provided to elderly living in old aged homes, the amount of drugs wasted from 3,020 residents ...
Chan, EW   +4 more
core   +2 more sources

Dietary Bioactives and Physical Activity in the Regulation of Hippocampal Neurogenesis and Cognitive Decline

open access: yesFood Science &Nutrition, Volume 14, Issue 3, March 2026.
Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley   +1 more source

Vascular Contributions to Cognitive Impairment and Treatments with Traditional Chinese Medicine [PDF]

open access: yes, 2016
published_or_final_versio
Chan, SW   +7 more
core   +1 more source

Mapping a novel positive allosteric modulator binding site in the central vestibule region of human P2X7 [PDF]

open access: yes, 2019
P2X7 receptors are important in the regulation of inflammatory responses and immune responses to intracellular pathogens such as Mycobacterium tuberculosis and Toxoplasma gondii.
Angulo, Jesus   +4 more
core   +3 more sources

Endometrial Stromal Cell Senescence: A Non‐Negligible Factor in Recurrent Pregnancy Loss

open access: yesiMetaMed, Volume 2, Issue 1, March 2026.
As populations age, links between female reproductive aging and infertility are increasingly evident. Cellular senescence, characterized by near‐irreversible cell‐cycle arrest and accumulation of damage, can impair tissue function. In the endometrium, aberrant senescence of endometrial stromal cells (EnSCs) may compromise receptivity, hinder embryo ...
Shuang Wu   +6 more
wiley   +1 more source

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