Selected ginsenosides of the prptopanaxdiol series are novel positive allosteric modulators of P2X7 receptors [PDF]
, 2015 Background and Purpose The P2X7 receptor is an ATP-gated ion channel predominantly expressed in immune cells and plays a key role in inflammatory processes.
Adinolfi +48 more
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Plants-derived neuroprotective agents: Cutting the cycle of cell death through multiple mechanisms [PDF]
, 2017 Neuroprotection is the preservation of the structure and function of neurons from insults arising from cellular injuries induced by a variety of agents or neurodegenerative diseases (NDs).
Berida, Tomayo Ireti +2 more
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Protective effect of ginsenoside Rg1 on glutamate-induced lung injury [PDF]
Acta Pharmacologica Sinica, 2007 To examine the possible protective effect of ginsenoside Rg1, an active component of ginseng, on lung injury caused by glutamate in vivo.The lungs of mice receiving glutamate (0.5 g/kg) and/or ginsenoside Rg1 (0.03 g/kg) via intraperitoneal administration were collected.
Li, Shen +7 more
openaire +2 more sources
Neural Plasticity, 2021 This study is aimed at investigating the potential roles of G protein-coupled estrogen receptor 1 (GPER, also known as GPR30) in the preventive effect of ginsenoside Rg1 against cognitive impairment and hippocampal cell apoptosis in experimental vascular
Fengming Shen +4 more
doaj +1 more source
Pharmacologically relevant drug interactions of sulfonylurea antidiabetics with common herbs [PDF]
, 2018 Introduction: Sulfonylurea antidiabetics are insulin secretogogues useful in the treatment of type 2 diabetic patients. The probability of adverse drug interactions is high in patients taking sulfonylureas and other drugs including herbal medicines ...
Balasubramaniam, Rajkapoor. +1 more
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Role of MicroRNA-214 in ginsenoside-Rg1-induced angiogenesis
European Journal of Pharmaceutical Sciences, 2009 MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional gene modulators. Ginsenoside-Rg1, one of the active components of ginseng, has been confirmed as an angiogenesis inducer. Using miRNA microarray analysis, a total of 17 (including miR-214) and 5 miRNAs were found to be down- or up-regulated by Rg1 in human umbilical vein ...
Lai-Sheung, Chan +3 more
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Analysis of Ginsenosides Rb1 and Rg1 Digestion Products in vitro Based on UHPLC-TSQ MS
Zhipu XuebaoA method of ultra-high-performance liquid chromatography-triple quadrupole mass spectrometry (UHPLC-TSQ MS) was used to study the products of protopanaxadiol ginsenoside Rb1 and protopanaxatriol ginsenoside Rg1 in simulated digestion solution in vitro ...
Hua-zhou NIU +4 more
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Ginsenoside Content of Berries and Roots of Three Typical Korean Ginseng () Cultivars
Natural Product Communications, 2009 The ginsenoside content of berries and roots of three cultivars of Korean ginseng have been investigated. For all cultivars, ginsenoside Re was the most abundant ginsenoside in roots and berries.
Yong Kyoung Kim +6 more
doaj +1 more source
Enzymatic transglycosylation of ginsenoside Rg1 by rice seed α-glucosidase [PDF]
Bioscience, Biotechnology, and Biochemistry, 2016 Abstract Six α-monoglucosyl derivatives of ginsenoside Rg1 (G-Rg1) were synthesized by transglycosylation reaction of rice seed α-glucosidase in the reaction mixture containing maltose as a glucosyl donor and G-Rg1 as an acceptor. Their chemical structures were identified by spectroscopic analysis, and the effects of reaction time, pH ...
Min-Ji, Kim +4 more
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Comparative study on saponin fractions from Panax notoginseng inhibiting inflammation-induced endothelial adhesion molecule expression and monocyte adhesion [PDF]
, 2011 Background: Panax notoginseng is commonly used for the treatment of cardiovascular diseases in China. The present study investigates the effects of three different saponin fractions (ie total saponins, PNS; protopanaxadiol-type saponin, PDS; and ...
Nan Wang +7 more
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