Results 41 to 50 of about 6,513 (215)
Frontiers in Immunology, 2018 Depression is considered a neuropsychiatric disease associated with various neuronal changes within specific brain regions. We previously reported that ginsenoside-Rg1, a potential neuroprotective agent extracted from ginseng, significantly alleviated ...
Cuiqin Fan +6 more
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Ginsenoside Rg1 suppresses cancer cell proliferation through perturbing mitotic progression
Journal of Ginseng Research, 2022 Background: Although the tumor-suppressive effects of ginsenosides in cell cycle have been well established, their pharmacological properties in mitosis have not been clarified yet.
Jihee Hong, Dasom Gwon, Chang-Young Jang
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Effects of Ginsenosides Rg1 on Osteoblasts Cultured with Ti Particles
Biomolecules and Therapeutics, 2012 The aim of this study was to explore the role and effect of ginsenosides Rg1 on osteoblasts cultured with Ti particles. Osteoblasts from neonatal rats were cultured with particles and different doses of Rg1, the main active ingredient in ginsenosides Rg1.
Lin, Yu +4 more
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Journal of Ethnopharmacology, 2023 ETHNOPHARMACOLOGICAL RELEVANCE Ginseng (Panax ginseng C. A. Mey) is a common traditional Chinese medicine used for anti-inflammation, treating colitis, type 2 diabetes, diarrhea, and recovering hepatobiliary function.
Q. Gao +10 more
semanticscholar +1 more source
Acta Pharmaceutica Sinica B, 2021 During the traumatic brain injury (TBI), improved expression of circulatory miR-21 serves as a diagnostic feature. Low levels of exosome-miR-21 in the brain can effectively improve neuroinflammation and blood–brain barrier (BBB) permeability, reduce ...
Ke-feng Zhai +11 more
semanticscholar +1 more source
Neural Regeneration Research, 2015 Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li +4 more
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Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis
Molecular Medicine Reports, 2013 Lidocaine, as an anesthetic substance, is often used for surface and spinal anesthesia. However, studies have shown that lidocaine may induce transient neurological symptoms and cauda equina syndrome. In the present study the effects of the ginsenoside Rg1 (Rg1) on lidocaine‑induced apoptosis were assessed in Jurkat cells using flow cytometry and ...
LI, HUI +3 more
openaire +3 more sources
International Journal of Nanomedicine, 2022 Wei Shang, Xin Zhao, Fan Yang, Dongyi Wang, Le Lu, Zihan Xu, Zhiming zhao, Hui Cai, Junyi Shen Department of Integrated Traditional and Western Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, People’s Republic of ...
Shang W +8 more
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A Preclinical Systematic Review of Ginsenoside‐Rg1 in Experimental Parkinson’s Disease [PDF]
Oxidative Medicine and Cellular Longevity, 2017 To date, no drug has been proven to be neuroprotective or disease‐modifying for Parkinson’s disease (PD) in clinical trials. Here, we aimed to assess preclinical evidence of Ginsenosides‐Rg1 (G‐Rg1), a potential neuroprotectant, for experimental PD and its possible mechanisms.
Liang Song +5 more
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Food & Function, 2023 Depression is a common psychological disease accompanied by mental disorders and somatic symptoms. However, the underlying mechanisms regarding the pathogenesis of depression are still not clear.
Wenjing Wang +8 more
semanticscholar +1 more source