Results 21 to 30 of about 6,472 (203)

Ginsenoside Rg1 inhibits dietary-induced obesity and improves obesity-related glucose metabolic disorders [PDF]

Brazilian Journal of Medical and Biological Research, 2018
Obesity and its consequent type 2 diabetes are significant threats to global health. Emerging evidence indicates that ginsenosides from ginseng (Panax ginseng) have anti-diabetic activity.
Jin-bo Li, Rui Zhang, Xiao Han, Chun-li Piao   +3 more
doaj   +4 more sources

Ginsenoside Rg1 alleviates chronic testicular damage caused by cranial irradiation through the SCF/PI3K/Akt/mTOR pathway in mice [PDF]

Radiation Medicine and Protection
Objective: To investigate whether Ginsenoside Rg1 can mitigate the adverse effects of cranial irradiation on distal reproductive function in mice and to explore the underlying mechanisms.
Qiuhua Zhou, Yiquan Ou, Xiangsheng Tian, Yujun Ning, Yuwei Mao, Weichao Zhao, Dingxin Long   +6 more
doaj   +2 more sources

Ginsenoside Rg1 Improves -produced Embryo Quality by Increasing Glucose Uptake in Porcine Blastocysts [PDF]

Asian-Australasian Journal of Animal Sciences, 2016
Ginsenoside Rg1 is a natural compound with various efficacies and functions. It has beneficial effects on aging, diabetes, and immunity, as well as antioxidant and proliferative functions. However, its effect on porcine embryo development remains unknown.
Seung-Hun Kim, Kwang-Hwan Choi, Dong-Kyung Lee, Jong-Nam Oh, Jae Yeon Hwang, Chi-Hun Park, Chang-Kyu Lee   +6 more
doaj   +3 more sources

Ginsenoside Rg1 can reverse fatigue behavior in CFS rats by regulating EGFR and affecting Taurine and Mannose 6-phosphate metabolism

Frontiers in Pharmacology, 2023
Background: Chronic fatigue syndrome (CFS) is characterized by significant and persistent fatigue. Ginseng is a traditional anti-fatigue Chinese medicine with a long history in Asia, as demonstrated by clinical and experimental studies.
Chaofang Lei, Jiaxu Chen, Jiaxu Chen, Zhen Huang, Yinian Men, Yue Qian, Mingzhi Yu, Xinyi Xu, Lin Li, Xin Zhao, Youming Jiang, Yueyun Liu   +11 more
doaj   +1 more source

Ginsenoside Rg1 inhibits nucleus pulposus cell apoptosis, inflammation and extracellular matrix degradation via the YAP1/TAZ pathway in rats with intervertebral disc degeneration

Journal of Orthopaedic Surgery and Research, 2022
Purpose Intervertebral disc degeneration (IDD) is one of the main causes of low back pain, which not only affects patients’ life quality, but also places a great burden on the public health system.
Yong-hua Yang, Xiao-peng Gu, Hong Hu, Bin Hu, Xiang-lian Wan, Zhi-ping Gu, Shao-jin Zhong   +6 more
doaj   +1 more source

Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells [PDF]

Frontiers in Pharmacology, 2020
Recently, breakthroughs have been made in the use of mesenchymal stem cells (MSCs) to treat various diseases. Several stem cell types have been authorized as drugs by the European Medicines Agency and the U.S. Food and Drug Administration. The Chinese official document "Notification of the management of stem cell clinical research (trial)" was also ...
Fang He, Fang He, Changyin Yu, Tao Liu, Huilin Jia   +4 more
openaire   +3 more sources

Ginsenoside Rg1 modulates intestinal microbiota and supports re-generation of immune cells in dexamethasone-treated mice [PDF]

, 2022
Ginsenoside Rg1 is one of the major ginsenosides found in roots of Panax ginseng and Panax notoginseng. Ginsenoside Rg1 is known to possess various biological activities including immunity enhancement activity.
Ding, Yan, Liu, He, Li, Ming, Ming Li, Zhang, Yingshu, Yan Ding, Yousuf, Sabiha, Hassan Ghayas, Danish Zahid, He Liu, Zahid, Danish, Zhang Yingshu, Sabiha Yousuf, Ghayas, Hassan, Li, Wenzhe, Wenzhe Li   +15 more
core   +1 more source

Ginsenoside Rg1 as a promising adjuvant agent for enhancing the anti-cancer functions of granulocytes inhibited by noradrenaline

Frontiers in Immunology, 2023
IntroductionIn recent years, numerous studies have confirmed that chronic stress is closely related to the development of cancer. Our previous research showed that high levels of stress hormones secreted in the body during chronic stress could inhibit ...
Yuqian Zhu, Jingyao Chen, Jun Li, Chenqi Zhou, Xin Huang, Bingdi Chen   +5 more
doaj   +1 more source

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy [PDF]

, 2022
Background: Alzheimer's disease (AD) is a common form of dementia, and impaired mitophagy is a hallmark of AD. Mitophagy is mitochondrial-specific autophagy. Ginsenosides from Ginseng involve in autophagy in cancer.
Ruijun Chen, Yuzhou Wang, Wang, Ni, Wang, Yuzhou, Liu, Yunyun, Song, Youqiang, Liu, Shunjie, Chen, Ruijun, Qingfeng Lei, Lu He, Youqiang Song, Shunjie Liu, Ni Wang, Li, Zhong, Yining Pan, Lei, Qingfeng, Zhong Li, He, Lu, Pan, Yining, Junyan Yang, Yunyun Liu, Yang, Junyan   +21 more
core   +1 more source

Host miR-129-5p reverses effects of ginsenoside Rg1 on morphine reward possibly mediated by changes in B. vulgatus and serotonin metabolism in hippocampus

Gut Microbes, 2023
Morphine addiction is closely associated with dysbiosis of the gut microbiota. miRNAs play a crucial role in regulating intestinal bacterial growth and are involved in the development of disease.
Chan Li, Yingbo Lin, Rukun Lin, Zhijie Chen, Qichun Zhou, Chaohua Luo, Zhixian Mo   +6 more
doaj   +1 more source