Protective effect of ginsenoside Rg1 on attenuating anti-GBM glomerular nephritis by activating NRF2 signalling [PDF]
Artificial Cells, Nanomedicine, and Biotechnology, 2019 Background/Aim Ginsenoside Rg1 exerts a beneficial effect in many kidney diseases. But little work has been done to confirm whether ginsenoside Rg1 could also exert a protective effect on anti-glomerular basement membrane (anti-GBM) glomerular nephritis (
Xiaojuan Guo +3 more
doaj +2 more sources
Ginsenoside Rg1 Protects Cardiomyocytes Against Hypoxia/Reoxygenation Injury via Activation of Nrf2/HO-1 Signaling and Inhibition of JNK [PDF]
Cellular Physiology and Biochemistry, 2017 Background/Aims: Excessive reactive oxygen species (ROS) disturb the physiology of H9c2 cells, which is regarded as a major cause of H9c2 cardiomyocyte apoptosis.
Qianhui Li +4 more
doaj +4 more sources
Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage [PDF]
Brazilian Journal of Medical and Biological Research, 2017 Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LPS ...
X.J. Ni +5 more
doaj +2 more sources
Ginsenoside Rg1 Nanoparticles Induce Demethylation of H3K27me3 in VEGF-A and Jagged 1 Promoter Regions to Activate Angiogenesis After Ischemic Stroke [PDF]
International Journal of Nanomedicine, 2022 Wei Shang, Xin Zhao, Fan Yang, Dongyi Wang, Le Lu, Zihan Xu, Zhiming zhao, Hui Cai, Junyi Shen Department of Integrated Traditional and Western Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, People’s Republic of ...
Shang W +8 more
doaj +1 more source
Neuroprotective effects of ginsenoside Rg1-induced neural stem cell transplantation on hypoxic-ischemic encephalopathy [PDF]
Neural Regeneration Research, 2015 Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li +4 more
doaj +2 more sources
Effects of Ginsenoside Rg1 on the Expression of Toll-Like Receptor 3, 4 and Their Signalling Transduction Factors in the NG108-15 Murine Neuroglial Cell Line [PDF]
Molecules, 2014 As one of the most important components of Panax ginseng, ginsenoside Rg1 has certain anti-aging effects, improving the activity of learning and memory.
Bao-Sheng Zhao +5 more
doaj +2 more sources
Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1 [PDF]
Journal of Ginseng Research, 2023 Rara vez se informan los efectos del ginsenósido principal Rg1 en la longevidad y la vitalidad física de los mamíferos. Para examinar la longevidad, el tumor y la actividad locomotora espontánea en ratas que consumen Rg1. Un total de 138 ratas Wistar se asignaron al azar en 2 grupos: control (N = 69) y Rg1 (N = 69).
Chao-Chieh Hsieh +8 more
openaire +4 more sources
Ginsenoside Rg1 prevents cognitive impairment and hippocampus senescence in a rat model of D-galactose-induced aging. [PDF]
PLoS ONE, 2014 Neurogenesis continues throughout the lifetime in the hippocampus, while the rate declines with brain aging. It has been hypothesized that reduced neurogenesis may contribute to age-related cognitive impairment. Ginsenoside Rg1 is an active ingredient of
Jiahong Zhu +9 more
doaj +3 more sources
Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats [PDF]
Frontiers in Immunology, 2018 Depression is considered a neuropsychiatric disease associated with various neuronal changes within specific brain regions. We previously reported that ginsenoside-Rg1, a potential neuroprotective agent extracted from ginseng, significantly alleviated ...
Cuiqin Fan +6 more
doaj +4 more sources
Protective effects of ginsenoside Rg1 against hydrogen peroxide-induced injury in human neuroblastoma cells [PDF]
Neural Regeneration Research, 2016 The active ingredient of ginseng, ginsenosides Rg1, has been shown to scavenge free radicals and improve antioxidant capacity. This study hypothesized that ginsenosides Rg1 has a protective role in human neuroblastoma cells injured by H2O2.
Zhi-gao Sun +4 more
doaj +2 more sources