Results 31 to 40 of about 8,086 (216)

Ginsenoside Rg1 as an Effective Regulator of Mesenchymal Stem Cells [PDF]

open access: yesFrontiers in Pharmacology, 2020
Recently, breakthroughs have been made in the use of mesenchymal stem cells (MSCs) to treat various diseases. Several stem cell types have been authorized as drugs by the European Medicines Agency and the U.S. Food and Drug Administration. The Chinese official document "Notification of the management of stem cell clinical research (trial)" was also ...
Fang He   +4 more
openaire   +3 more sources

Improvement of Memory in Mice and Increase of Hippocampal Excitability in Rats by Ginsenoside Rg1’s Metabolites Ginsenoside Rh1 and Protopanaxatriol

open access: yesJournal of Pharmacological Sciences, 2009
Ginsenoside Rg1 has been reported to improve cognitive function in many memory-impaired animal models. However, little is known about the bioactivity of its metabolites in the central nervous system in vivo.
Yu-Zhu Wang   +6 more
doaj   +1 more source

Neuroprotective Effects of Ginsenoside-Rg1 Against Depression-Like Behaviors via Suppressing Glial Activation, Synaptic Deficits, and Neuronal Apoptosis in Rats

open access: yesFrontiers in Immunology, 2018
Depression is considered a neuropsychiatric disease associated with various neuronal changes within specific brain regions. We previously reported that ginsenoside-Rg1, a potential neuroprotective agent extracted from ginseng, significantly alleviated ...
Cuiqin Fan   +6 more
doaj   +1 more source

Ginsenoside Rg1 as a Potential Regulator of Hematopoietic Stem/Progenitor Cells [PDF]

open access: yesStem Cells International, 2021
Ginsenoside Rg1 (Rg1), a purified, active component of the root or stem of ginseng, exerts positive effects on mesenchymal stem cells (MSCs). Many recent studies have found that hematopoietic stem cells (HSCs), which can develop into hematopoietic progenitor cells (HPCs) and mature blood cells, are another class of heterogeneous adult stem cells that ...
Fang He, Guanping Yao
openaire   +3 more sources

Protective effect of ginsenoside Rg1 on lidocaine-induced apoptosis

open access: yesMolecular Medicine Reports, 2013
Lidocaine, as an anesthetic substance, is often used for surface and spinal anesthesia. However, studies have shown that lidocaine may induce transient neurological symptoms and cauda equina syndrome. In the present study the effects of the ginsenoside Rg1 (Rg1) on lidocaine‑induced apoptosis were assessed in Jurkat cells using flow cytometry and ...
LI, HUI   +3 more
openaire   +3 more sources

Oral Rg1 supplementation strengthens antioxidant defense system against exercise-induced oxidative stress in rat skeletal muscles [PDF]

open access: yes, 2012
BACKGROUND: Previous studies reported divergent results on nutraceutical actions and free radical scavenging capability of ginseng extracts. Variations in ginsenoside profile of ginseng due to different soil and cultivating season may contribute to the ...
Chia-Hua Kuo   +10 more
core   +1 more source

Neuroprotective effects of ginsenoside Rg1-induced neural stem cell transplantation on hypoxic-ischemic encephalopathy

open access: yesNeural Regeneration Research, 2015
Ginsenoside Rg1 is the major pharmacologically active component of ginseng, and is reported to have various therapeutic actions. To determine whether it induces the differentiation of neural stem cells, and whether neural stem cell transplantation after ...
Ying-bo Li   +4 more
doaj   +1 more source

Longevity, tumor, and physical vitality in rats consuming ginsenoside Rg1

open access: yesJournal of Ginseng Research, 2023
Rara vez se informan los efectos del ginsenósido principal Rg1 en la longevidad y la vitalidad física de los mamíferos. Para examinar la longevidad, el tumor y la actividad locomotora espontánea en ratas que consumen Rg1. Un total de 138 ratas Wistar se asignaron al azar en 2 grupos: control (N = 69) y Rg1 (N = 69).
Chao-Chieh Hsieh   +8 more
openaire   +3 more sources

Ginsenoside Rg1 Nanoparticles Induce Demethylation of H3K27me3 in VEGF-A and Jagged 1 Promoter Regions to Activate Angiogenesis After Ischemic Stroke

open access: yesInternational Journal of Nanomedicine, 2022
Wei Shang, Xin Zhao, Fan Yang, Dongyi Wang, Le Lu, Zihan Xu, Zhiming zhao, Hui Cai, Junyi Shen Department of Integrated Traditional and Western Medicine, Jinling Hospital, School of Medicine, Nanjing University, Nanjing, 210002, People’s Republic of ...
Shang W   +8 more
doaj  

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke [PDF]

open access: yesScientific Reports, 2015
The neuroprotective actions of Ginsenoside-Rg1 (G-Rg1) have been documented for experimental stroke therapy. We used a systematic review and meta-analysis to assess the efficacy of G-Rg1 in experimental ischemic stroke. We identified studies describing the efficacy of G-Rg1 in animal models of focal cerebral ischemia.
Xie, Cheng-long   +5 more
openaire   +2 more sources

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