Results 31 to 40 of about 6,513 (215)

A systematic review and meta-analysis of Ginsenoside-Rg1 (G-Rg1) in experimental ischemic stroke [PDF]

Scientific Reports, 2015
The neuroprotective actions of Ginsenoside-Rg1 (G-Rg1) have been documented for experimental stroke therapy. We used a systematic review and meta-analysis to assess the efficacy of G-Rg1 in experimental ischemic stroke. We identified studies describing the efficacy of G-Rg1 in animal models of focal cerebral ischemia.
Xie, Cheng-long, Wang, Wen-Wen, Xue, Xiao-Dong, Zhang, Su-fang, Gan, Jing, Liu, Zhen-Guo   +5 more
openaire   +2 more sources

Ginsenoside Rg1 ameliorates Alzheimer's disease pathology via restoring mitophagy

Journal of Ginseng Research, 2022
Background Alzheimer's disease (AD) is a common form of dementia, and impaired mitophagy is a hallmark of AD. Mitophagy is mitochondrial-specific autophagy. Ginsenosides from Ginseng involve in autophagy in cancer.
Ni Wang, Junyan Yang, Ruijun Chen, Yunyun Liu, Shunjie Liu, Yining Pan, Qingfeng Lei, Yuzhou Wang, Lu He, Youqiang Song, Zhong Li   +10 more
semanticscholar   +1 more source

Ginsenoside Rg1 attenuates the NASH phenotype by regulating the miR-375-3p/ATG2B/PTEN-AKT axis to mediate autophagy and pyroptosis

Lipids in Health and Disease, 2023
Background Nonalcoholic steatohepatitis (NASH) is one of the most frequent liver diseases at present, and there is no radical treatment. The consequences of a variety of ginsenoside compounds on this situation have before been reported, however, the ...
Xuanxin Chen, W. Xue, Jia Zhang, Jiayi Peng, Wenxia Huang   +4 more
semanticscholar   +1 more source

Ginsenoside Rg1 Protects Cardiomyocytes Against Hypoxia/Reoxygenation Injury via Activation of Nrf2/HO-1 Signaling and Inhibition of JNK

Cellular Physiology and Biochemistry, 2017
Background/Aims: Excessive reactive oxygen species (ROS) disturb the physiology of H9c2 cells, which is regarded as a major cause of H9c2 cardiomyocyte apoptosis.
Qianhui Li, Yin Xiang, Yu Chen, Yong Tang, Yachen Zhang   +4 more
doaj   +1 more source

Immunomodulating Activity of Ginsenoside Rg1 from Panax Ginseng

Japanese Journal of Pharmacology, 1990
The immunomodulatory activity of ginsenoside Rg1 from Panax ginseng was studied in mice using sheep red cells as the antigen. It was found that ginsenoside Rg1 at a dose of 10 mg/kg administered for three consecutive days before immunization increased the number of spleen plaque-forming cell, the titers of sera hemagglutinins as well as the number of ...
KENAROVA, Buriana, NEYCHEV, Hristo, HADJIIVANOVA, Christina, PETKOV, Vesselin D.   +3 more
openaire   +3 more sources

Ginsenoside Rg1 protects human renal tubular epithelial cells from lipopolysaccharide-induced apoptosis and inflammation damage

Brazilian Journal of Medical and Biological Research, 2017
Ginsenoside Rg1, one of the most notable active components of Panax ginseng, has been widely reported to exert anti-inflammatory actions. This study aimed to reveal whether ginsenoside Rg1 also exhibits beneficial roles against lipopolysaccharide (LPS ...
X.J. Ni, Z.Q. Xu, H. Jin, S.L. Zheng, Y. Cai, J.J. Wang   +5 more
doaj   +1 more source

Ginsenoside Rg1 interferes with the progression of diabetic osteoporosis by promoting type H angiogenesis modulating vasculogenic and osteogenic coupling

Frontiers in Pharmacology, 2022
Ginsenoside Rg1 (Rg1) has been demonstrated to have antidiabetic and antiosteoporotic activities. The aim of this study was to investigate the protective effect of Rg1 against diabetic osteoporosis and the underlying mechanism.
Wenhui Chen, Xinyan Jin, Tingli Wang, Ruibin Bai, Jun Shi, Yunxia Jiang, Simin Tan, Ruijie Wu, Shiqi Zeng, Hongxiang Zheng, Hongyan Jia, Shuanglei Li   +11 more
semanticscholar   +1 more source

Effects of Dietary Ginsenoside Rg1 Supplementation on Growth Performance, Gut Health, and Serum Immunity in Broiler Chickens

Frontiers in Nutrition, 2021
The restriction and banning of antibiotics in farm animal feed has led to a search for promising substitutes for antibiotics to promote growth and maintain health for livestock and poultry.
Zehe Song, Zehe Song, Zehe Song, Zehe Song, Kaihuan Xie, Yunlu Zhang, Qian Xie, Xi He, Xi He, Xi He, Xi He, Haihan Zhang, Haihan Zhang, Haihan Zhang, Haihan Zhang   +14 more
doaj   +1 more source

Role of MicroRNA-214 in ginsenoside-Rg1-induced angiogenesis

European Journal of Pharmaceutical Sciences, 2009
MicroRNAs (miRNAs) are small non-coding RNAs that act as post-transcriptional gene modulators. Ginsenoside-Rg1, one of the active components of ginseng, has been confirmed as an angiogenesis inducer. Using miRNA microarray analysis, a total of 17 (including miR-214) and 5 miRNAs were found to be down- or up-regulated by Rg1 in human umbilical vein ...
Lai-Sheung, Chan, Patrick Ying-Kit, Yue, Nai-Ki, Mak, Ricky Ngok-Shun, Wong   +3 more
openaire   +2 more sources

Ginsenoside Rg1 improves hypoxia-induced pulmonary vascular endothelial dysfunction through TXNIP/NLRP3 pathway-modulated mitophagy. [PDF]

J Ginseng Res
Background Vascular endothelial dysfunction (VED) is one of the main pathogenic events in pulmonary arterial hypertension (PAH). Previous studies have demonstrated that the ginsenoside Rg1 (Rg1) can ameliorate PAH, but the mechanism by which Rg1 affects ...
Zhang R, Lu M, Ran C, Niu L, Qi Q, Wang H.   +5 more
europepmc   +2 more sources