Results 81 to 90 of about 7,976 (200)

New Insights Into Ginseng and Clove Supplementation: Alleviating Obesity by Reducing Leptin Resistance and Reshaping the Gut Microbiota

Food Frontiers, Volume 7, Issue 1, January 2026.
AEGC conferred substantial resistance to weight gain and reduced food intake. AEGC may alleviate LR by regulating the levels of LEP and ADP. AEGC elevated the diversity of gut microbiota and reconstructed the composition. Changes such as CAG‐873 in gut microbiota may be the reason why AEGC alleviates LR.
Weifeng Ni, Shen Yao, Shichao Li, Shichao Liu, Liwei Sun, Daqing Zhao, Zhengqi Dong, Siming Wang, Weinan Wang, Meichen Liu   +9 more
wiley   +1 more source

Protective Effects of Ginsenoside Rg1 on Acute Myocardial Infarction

Journal of Pharmacy and Pharmacology Research, 2020
Context: Ginsenoside Rg1 (Rg1), as the active ingredient of Panax notoginseng, has protective effect on the cardiovascular system. While, the efficiency of Rg1 against acute myocardial infarction (MI) is not fully elucidated. The aim of this study was to investigate the cardio-protection and the underlying mechanism for Rg1.
Xiaoyu Wang, Linlin Wang, Lili Qi, Huimiao Bian, Xing Yan, Yan Wang, Xiaodong Li, Kenka Cho, Guojiang Wu, Baohong Jiang   +9 more
openaire   +1 more source

Ginsenoside Rg1 alleviates chronic testicular damage caused by cranial irradiation through the SCF/PI3K/Akt/mTOR pathway in mice

Radiation Medicine and Protection
Objective: To investigate whether Ginsenoside Rg1 can mitigate the adverse effects of cranial irradiation on distal reproductive function in mice and to explore the underlying mechanisms.
Qiuhua Zhou, Yiquan Ou, Xiangsheng Tian, Yujun Ning, Yuwei Mao, Weichao Zhao, Dingxin Long   +6 more
doaj   +1 more source

Lclet 4 enhances pro-apoptotic and anti-invasive effects of mitoxantrone on human prostate cancer cells : in vitro study [PDF]

, 2013
Triterpene saponosides are widely distributed plant secondary metabolites characterized by relatively low systemic cytotoxicity and a range of biological activities. These include anti-inflammatory, antimicrobial, vasoprotective and antitumor properties.
Czyż, Jarosław, Galanty, Agnieszka, Koczurkiewicz, Paulina, Madeja, Zbigniew, Michalik, Marta, Podolak, Irma, Wojcik, Katarzyna Anna   +6 more
core   +1 more source

Medicinal Plants and Lead Phytomolecules as Immunomodulators: An Updated Review

BioMed Research International, Volume 2026, Issue 1, 2026.
All therapeutic interventions aimed at modulating the immune response to pathogens, self‐antigens, carcinogens, or xenogeneic antigens are referred to as immunomodulation, which either prevents hyperactivation or restores the appropriate response of the immune system.
Gurdeep Singh, Vikas Sharma, Blessing Nnenna Udeh, Baisakhi Banerjee   +3 more
wiley   +1 more source

Antidepressant-like Effects of Ginsenoside Rg1 in the Chronic Restraint Stress-induced Rat Model

Digital Chinese Medicine, 2019
Objective: To investigate the ameliorating effect of ginsenoside Rg1 on the depression-like behaviors induced by chronic restraint stress (CRS) in rats and the underlying mechanisms. Methods: Forty male Wistar rats were divided into 4 groups according to
Jiang Ning, Lv Jing-Wei, Wang Hai-Xia, Huang Hong, Wang Qiong, Chen Shan-Guang, Qu Li-Na, Alberto Carlos Pires Dias, Liu Xin-Min   +8 more
doaj   +1 more source

Characterization and Mechanism Prediction of Active Components in Fuganlin Oral Liquid for Respiratory Tract Infections Using UPLC–Q‐TOF–MS and Network Pharmacology

Journal of Analytical Methods in Chemistry, Volume 2026, Issue 1, 2026.
Fuganlin oral liquid (FOL) has been clinically employed for the treatment of pediatric qi deficiency colds, manifesting symptoms such as fever, cough, asthma, and sore throat. However, the chemical composition and bioactive components of FOL have not been clearly elucidated.
Mengyue Zhang, Feng Han, Mingxuan Yang, Zhishan Ye, Ying Cui, Yuefei Wang, Jing Yang, Xin Chai, Rongda Xu   +8 more
wiley   +1 more source

Characterization of Chondrogenic Gene Expression and Cartilage Phenotype Differentiation in Human Breast Adipose-Derived Stem Cells Promoted by Ginsenoside Rg1 In Vitro

Cellular Physiology and Biochemistry, 2015
Background/Aims: Investigating and understanding chondrogenic gene expression during the differentiation of human breast adipose-derived stem cells (HBASCs) into chondrogenic cells is a prerequisite for the application of this approach for cartilage ...
Fang-Tian Xu, Hong-Mian Li, Cheng-Yi Zhao, Zhi-Jie Liang, Min-Hong Huang, Qing Li, Ying-Chao Chen, Gang-Yi Chi   +7 more
doaj   +1 more source

Bidirectional Regulation of NLRP3 Inflammasome and Mitochondrial Quality Control in Sepsis: Mechanisms and Therapeutic Implications

Mediators of Inflammation, Volume 2026, Issue 1, 2026.
Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao, Yixun Wang, Zhaohui Zhang, Xingguang Qu, Gaosheng Zhou, Laurent L′homme   +5 more
wiley   +1 more source

Antidepressant-like effects of Rg1 by mycn: promotion of neurogenesis in the hippocampus

Frontiers in Pharmacology
Ginsenoside Rg1 has been shown to have antidepressant effects by increasing hippocampal neurogenesis, but the molecular mechanisms remain unclear. In this research, we showed that Rg1 has antidepressant-like effects by increasing neurogenesis in the ...
Enze Shi, Yiwei Zhang, Yanyan Fan, Jiangfan Chen, Linfeng Xu, Jiao Chen   +5 more
doaj   +1 more source