Results 91 to 100 of about 20,751 (192)

Ginsenoside Rg3 suppresses vasculogenic mimicry by impairing DVL3-maintained stemness via PAAD cell-derived exosomal miR-204 in pancreatic adenocarcinoma.

Phytomedicine
BACKGROUND Vasculogenic mimicry (VM) is an angiogenesis-independent process that potentially contributes to the poor clinical outcome of anti-angiogenesis therapy in multiple malignant cancers, including pancreatic adenocarcinoma (PAAD).
Xufan Cai, Zhaohong Wang, Shengzhang Lin, Hui Chen, Heqi Bu   +4 more
semanticscholar   +1 more source

Ginsenoside Rg3 Induces Apoptosis in B16F10 Melanoma Cells

Journal of Life Science, 2014
Ginsenoside Rg3 is one of the active ingredients extracted from red ginseng, and it is an effective chemical component of the human body and well known in herbal medicine as a restorative agent. Several studies have shown that Rg3 has a potent anti-tumor effect on various cancer cell lines. However, Rg3-induced apoptosis in B16F10 melanoma cancer cells
Seul Gi Lee, Byung Soo Kim, Ju-Ock Nam
openaire   +2 more sources

Natural Products in Cancer Prevention and Therapy: Current Challenges and Future Directions

MedComm, Volume 7, Issue 2, February 2026.
Natural products play a pivotal role in cancer therapy. They induce cancer cell death by reprogramming four metabolic pathways while precisely targeting the tumor microenvironment and immune cells. These compounds not only leverage novel delivery systems for innovative applications but also demonstrate unique therapeutic efficacy across clinical stages:
Ruimiao Qian, Jun Ge, Ni Fan, Zheng Sun, Chengcheng Zhao, Yujiao Sun, Yingpeng Li, Yunfei Li, Hui Fu   +8 more
wiley   +1 more source

Stereoselective Anti-Cancer Activities of Ginsenoside Rg3 on Triple Negative Breast Cancer Cell Models

Pharmaceuticals, 2019
Ginsenoside Rg3 (Rg3) has two epimers, 20(S)-ginsenoside Rg3 (SRg3) and 20(R)-ginsenoside Rg3 (RRg3), and while Rg3 itself has been reported to have anti-cancer properties, few studies have been reported on the anti-cancer effects of the different ...
Maryam Nakhjavani, Helen M. Palethorpe, Yoko Tomita, Eric Smith, Timothy J. Price, Andrea J. Yool, Jinxin V. Pei, Amanda R. Townsend, Jennifer E. Hardingham   +8 more
doaj   +1 more source

Traditional Chinese Medicine Modernization in Diagnosis and Treatment: Utilizing Artificial Intelligence and Nanotechnology

MedComm, Volume 7, Issue 2, February 2026.
Traditional Chinese medicine (TCM) faces great challenges during the development of modern medicine. Utilizing novel technologies such as artificial intelligence (AI) and nanotechnology facilitates TCM with great potential in precision diagnosis and improved treatments efficacy.
Wenqi Yu, Mengzhen Chen, Xueqi Tan, Xi Wei, Fan Sun, Hua Yan, Xue Xu, Hongcai Shang   +7 more
wiley   +1 more source

Beneficial effects of fermented black ginseng and its ginsenoside 20(S)-Rg3 against cisplatin-induced nephrotoxicity in LLC-PK1 cells

Journal of Ginseng Research, 2016
Background: Nephrotoxicity is a common side effect of medications. Panax ginseng is one of the best-known herbal medicines, and its individual constituents enhance renal function.
Myoung-Sik Han, Im-Ho Han, Dahae Lee, Jun Min An, Su-Nam Kim, Myoung-Sook Shin, Noriko Yamabe, Gwi Seo Hwang, Hye Hyun Yoo, Suk-Jung Choi, Ki Sung Kang, Hyuk-Jai Jang   +11 more
doaj   +1 more source

Prevention of In‐Stent Restenosis After PCI by Saponin Natural Products: Inhibition of Platelet Activation

Journal of Cellular and Molecular Medicine, Volume 30, Issue 3, February 2026.
ABSTRACT Percutaneous coronary intervention (PCI) enables coronary revascularisation and restores haemodynamic stability but also carries risks of delayed complications including in‐stent restenosis (ISR), a chronic progressive disease with endovascular damage after PCI, which compromises the long‐term efficacy of PCI.
Xueli Lei, Chunlei Lv, Yu Zhang, Zhiyu Li, Hao Shen, Li Zhu   +5 more
wiley   +1 more source

Multifunctional Hydrogel‐Based wound Dressings for Scar‐Free Healing: Design Principles, Therapeutic Mechanisms, and Clinical Translation Challenges

Advanced NanoBiomed Research, Volume 6, Issue 1, January 2026.
This review integrates scar biology with hydrogel‐based therapeutic strategies, offering a phase‐specific framework to correlate hydrogel functions with scar‐influencing events. It highlights innovations such as stimuli‐responsive hydrogels, nanocomposite systems, and 3D‐printed scaffolds, while addressing clinical translation challenges like ...
Haonan Chai, Zhenxing Wang, Jingyi Ju, Jiaming Sun   +3 more
wiley   +1 more source

Ginsenoside Rg3 Improves Erectile Function in Streptozotocin-Induced Diabetic Rats

The Journal of Sexual Medicine, 2015
ABSTRACT Introduction Ginsenoside Rg3 is one of the active ingredients isolated from Panax ginseng C.A. Meyer. Previous studies demonstrated that Rg3 has antioxidant and neuroprotective abilities. Aim The purpose of this study was to ...
Tao, Liu, Yi-Feng, Peng, Chao, Jia, Ben-Hai, Yang, Xia, Tao, Jing, Li, Xiang, Fang   +6 more
openaire   +2 more sources

Evaluation of Ginsenosides and Their Derivatives From Panax ginseng as Aromatase Inhibitors for Breast Cancer Treatment—An in silico study

BioMed Research International, Volume 2026, Issue 1, 2026.
Breast cancer, particularly estrogen receptor‐positive subtypes, is a leading cause of cancer‐related mortality worldwide. Aromatase inhibitors, which target estrogen biosynthesis, are a cornerstone of therapeutic intervention. Panax ginseng, a widely recognized medicinal herb, contains bioactive compounds known as ginsenosides, which possess various ...
Jayasri Gokila Madhan, Surya Sekaran, Rajeswari Nambirajan Akshaya, Khavyanjali Venkatesan, Kavin Kirupanandasamy, Kiruthika Vijayakumar, Nancy Jenifer, Benedict Christopher Paul, Abhishek Tyagi   +8 more
wiley   +1 more source