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Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats
Toxicology, 2018Ginsenoside Rg3 (Rg3) is one of the key components of a frequently used herbal tonic panax ginseng for fatigue treatment. However, the molecular mechanisms of Rg3 on anti-fatigue effects have not been completely understood yet.We built a postoperative fatigue syndrome (POFS) model and tried to elucidate the molecular mechanisms responsible for anti ...
Qi-Yu, Yang +3 more
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Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells
Archives of Pharmacal Research, 2004Ginseng has an anti-cancer effect in several cancer models. This study was to characterize active constituents of ginseng and their effects on proliferation of prostate cancer cell lines, LNCaP and PC3. Cell proliferation was measured by [3H]thymidine incorporation, the intracellular calcium concentration by a dual-wavelength spectrophotometer system ...
Hyun-Sook, Kim +5 more
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Characteristics of Ginsenoside Rg3-Mediated Brain Na+ Current Inhibition
Molecular Pharmacology, 2005We demonstrated previously that ginsenoside Rg(3) (Rg(3)), an active ingredient of Panax ginseng, inhibits brain-type Na(+) channel activity. In this study, we sought to elucidate the molecular mechanisms underlying Rg(3)-induced Na(+) channel inhibition. We used the two-microelectrode voltage-clamp technique to investigate the effect of Rg(3) on Na(+)
Jun-Ho, Lee +13 more
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[Raman spectroscopy study on the structure of ginsenoside Rg3].
Guang pu xue yu guang pu fen xi = Guang pu, 2010Ginsenoside Rg3, discovered from Red Panax ginseng, is a new anticancer agent, which shows inhibitive activities of tumor metastasis in mice and in vitro tumor cell invasion. There are two isomers for ginsenoside Rg3: 20-(R)-Rg3 and 20-(S)-Rg3. The research on the Rg3 structure is limitted, with no report on the use of Raman spectroscopy in such ...
Xiao-Bo, Qu +5 more
openaire +1 more source
Ginsenoside Rg3 suppresses the NLRP3 inflammasome activation through inhibition of its assembly
FASEB Journal, 2020Mengjie Zheng, Wei Xu, Fushan Shi
exaly
Ginsenoside Rg3 improves cyclophosphamide-induced immunocompetence in Balb/c mice
International Immunopharmacology, 2019Liu Xiao, Jinghua Liu, Qⅰan Zhou
exaly

