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Effects of Ginsenoside Rg3 on fatigue resistance and SIRT1 in aged rats

Toxicology, 2018
Ginsenoside Rg3 (Rg3) is one of the key components of a frequently used herbal tonic panax ginseng for fatigue treatment. However, the molecular mechanisms of Rg3 on anti-fatigue effects have not been completely understood yet.We built a postoperative fatigue syndrome (POFS) model and tried to elucidate the molecular mechanisms responsible for anti ...
Qi-Yu, Yang   +3 more
openaire   +2 more sources

Effects of ginsenosides Rg3 and Rh2 on the proliferation of prostate cancer cells

Archives of Pharmacal Research, 2004
Ginseng has an anti-cancer effect in several cancer models. This study was to characterize active constituents of ginseng and their effects on proliferation of prostate cancer cell lines, LNCaP and PC3. Cell proliferation was measured by [3H]thymidine incorporation, the intracellular calcium concentration by a dual-wavelength spectrophotometer system ...
Hyun-Sook, Kim   +5 more
openaire   +2 more sources

Characteristics of Ginsenoside Rg3-Mediated Brain Na+ Current Inhibition

Molecular Pharmacology, 2005
We demonstrated previously that ginsenoside Rg(3) (Rg(3)), an active ingredient of Panax ginseng, inhibits brain-type Na(+) channel activity. In this study, we sought to elucidate the molecular mechanisms underlying Rg(3)-induced Na(+) channel inhibition. We used the two-microelectrode voltage-clamp technique to investigate the effect of Rg(3) on Na(+)
Jun-Ho, Lee   +13 more
openaire   +2 more sources

[Raman spectroscopy study on the structure of ginsenoside Rg3].

Guang pu xue yu guang pu fen xi = Guang pu, 2010
Ginsenoside Rg3, discovered from Red Panax ginseng, is a new anticancer agent, which shows inhibitive activities of tumor metastasis in mice and in vitro tumor cell invasion. There are two isomers for ginsenoside Rg3: 20-(R)-Rg3 and 20-(S)-Rg3. The research on the Rg3 structure is limitted, with no report on the use of Raman spectroscopy in such ...
Xiao-Bo, Qu   +5 more
openaire   +1 more source

Ginsenoside Rg3

2018
Zhen-Zhen Wang   +2 more
openaire   +1 more source

Metabolism of 20(S)- and 20(R)-Ginsenoside Rg3 by Human Intestinal Bacteria and Its Relation to in Vitro Biological Activities.

Biological and Pharmaceutical Bulletin, 2002
Eun-Ah Bae   +2 more
exaly  

Ginsenoside Rg3 improves cyclophosphamide-induced immunocompetence in Balb/c mice

International Immunopharmacology, 2019
Liu Xiao, Jinghua Liu, Qⅰan Zhou
exaly  

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