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Dissolvable microneedles loaded ginsenoside Rg3 liposome: a transdermal delivery approach for alopecia treatment. [PDF]

open access: yesRegen Biomater
Yang Q   +11 more
europepmc   +1 more source

Ginsenoside Rg3 targets glycosylation of PD-L1 to enhance anti-tumor immunity in non-small cell lung cancer. [PDF]

open access: yesFront Immunol
Wang W   +12 more
europepmc   +1 more source
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Insights into the antitumor mechanism of ginsenosides Rg3

Molecular Biology Reports, 2021
Panax ginseng, an ancient herb, belonging to Chinese traditional medicine, is an important herb that has a remarkable impact on various diseases. Ginsenoside Rg3, one of the most abundant ginsenosides, exerts significant functions in the prevention of various types of cancers with few side effects.
Zongyu Liu   +5 more
openaire   +2 more sources

Multifunctional ginsenoside Rg3-based liposomes for glioma targeting therapy

Journal of Controlled Release, 2021
Liposomes have been widely used for targeted drug delivery. However, nonselective distribution, low blood-brain barrier penetration, and the disadvantages of cholesterol greatly limit the application of conventional liposomes in the treatment of brain tumors.
Ying, Zhu   +13 more
openaire   +2 more sources

Ginsenoside Rb1 and Rg3 Attenuate Glucocorticoid-Induced Neurotoxicity

Cellular and Molecular Neurobiology, 2010
Glucocorticoid (GC) hormones, increased in response to stress, can cause neuronal loss. We tested the effect of GC hormone on cell viability of neural SHSY-5Y cells and protective effects of ginsenoside Rb1 and Rg3 on the action of GC. We treated SHSY-5Y cells with increasing concentrations of synthetic GC dexamethasone (DEX; 10, 25, 50, and 100 nM ...
Sung-Ok, Kim   +8 more
openaire   +2 more sources

The angiosuppressive effects of 20(R)- ginsenoside Rg3

Biochemical Pharmacology, 2006
Aberrant angiogenesis is an essential step for the progression of solid tumors. Thus anti-angiogenic therapy is one of the most promising approaches to control tumor growth. In this study, we examined the ability of 20(R)-ginsenoside Rg3 (Rg3), one of the active compounds present in ginseng root, to interfere with the various steps of angiogenesis. Rg3
Patrick Y K, Yue   +10 more
openaire   +2 more sources

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