Results 111 to 120 of about 25,297 (234)

Ginseng Volatile Oil Alleviates Loperamide‐Induced Constipation in Mice by Regulating the Microbiota/Metabolism/Neural Network

Food Frontiers, Volume 7, Issue 2, March 2026.
GVO relieves constipation mechanisms. GVO decreased the abundance of Firmicutes and increased that of Bacteroidota, thereby ameliorating Lop‐induced gut microbial imbalances. Then the level of 8,9‐DiHETrE was raised, whereas the level of 15(S)‐HpETE was lowered.
Yanan Xu, Mingyue Wang, Meixin Chen, Zhilong Wang, Baoyue Zhang, Xin Wang, Liying Shang, Lequn Zhang, Bowen Sui, Wei Zhang, Jingzhou Zhang, Xueyuan Bai   +11 more
wiley   +1 more source

Profiling the Differential Distribution of Ginsenosides Across Ginseng Tissues Using High-Resolution Mass Spectrometry

Separations
This study investigates the compositional characteristics and quantitative differences of ginsenosides across various ginseng tissues, with a particular focus on the specific accumulation patterns of malonyl ginsenosides.
Hang Xu, Zheng Li, Chong Liu, Yukun Wang, Siwei Qiao, Hao Zhang   +5 more
doaj   +1 more source

Obesity and Natural Products: Mechanisms, Therapeutic Potential, and Future Directions

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Natural products such as EGCG, berberine, curcumin, and capsaicin modulate key metabolic pathways including AMPK activation, adipogenesis inhibition, and inflammatory signaling. While clinical trials demonstrate modest benefits on body weight and metabolic parameters, translational challenges related to bioavailability, dose feasibility, and regulatory
Ohoud M. Marie, Abdelghafar Abu‐Elsaoud   +1 more
wiley   +1 more source

Dietary Bioactives and Physical Activity in the Regulation of Hippocampal Neurogenesis and Cognitive Decline

Food Science &Nutrition, Volume 14, Issue 3, March 2026.
Exercise and dietary polyphenols enhance hippocampal plasticity and cognitive function via complementary molecular mechanisms. Central pathways include BDNF signaling, inflammation control, and mitochondrial regulation. Although synergy is mainly supported by preclinical data, lifestyle‐based strategies show promise for brain health maintenance ...
Zhenyi Zhao, Sima‐sadat Sabihi
wiley   +1 more source

Ginsenoside Rb1 Targets the HRD1‐STING Axis to Mitigate Cholesterol‐Induced VSMC Senescence

Journal of Clinical Laboratory Analysis, Volume 40, Issue 5, March 2026.
Schematic representation of the proposed mechanism of action for Ginsenoside Rb1. Suppression of HRD1 expression in VSMCs cholesterol stimulation, leading to ER stress (BiP/XBP1s upregulation), STING pathway activation, ROS accumulation (including mitochondrial ROS), and ultimately, VSMC senescence.
Haiming Niu, Yingzhang Cai, Conghui Yu, Ning Lin, Miaolian Chen, Linli Wang   +5 more
wiley   +1 more source

In Vitro Evaluation of the Inhibitory Effects of Linarin on Histamine‐Induced Expression of Proinflammatory Cytokines, Mucin 5AC, and Aquaporin 5 in Human Nasal and Bronchial Epithelial Cells

The Kaohsiung Journal of Medical Sciences, Volume 42, Issue 3, March 2026.
ABSTRACT Allergic rhinitis and asthma are two prevalent chronic allergic conditions in children. Linarin, a glycosylated flavonoid derived from various plants, exhibits a wide range of biological activities. This study aimed to investigate the therapeutic potential of linarin against allergic rhinitis and asthma.
Xin‐Jing Mi, Jie Wang, Jian‐Qiang Qi
wiley   +1 more source

Biotransformation of Ginsenoside Rb1 to Ginsenoside Rd and 7 Rare Ginsenosides Using Irpex lacteus with HPLC-HRMS/MS Identification

ACS Omega
The biotransformation of ginsenosides using microorganisms represents a promising and ecofriendly approach for the production of rare ginsenosides. The present study reports on the biotransformation of ginsenoside Rb1 using the fungus Irpex lacteus, resulting in the production of ginsenoside Rd and seven rare ginsenosides with novel structures ...
Yue Gao, Yadong Feng, Yanyan Chang, Zhu Zhu, Huanxi Zhao, Wei Xu, Mengya Zhao, Yusheng Xiao, Lu Tian, Yang Xiu   +9 more
openaire   +3 more sources

Direct Ambient Mass Spectrometry for Food, Beverage, and Agricultural Sample Analysis and Research

Mass Spectrometry Reviews, Volume 45, Issue 2, Page 429-452, March/April 2026.
ABSTRACT Ambient and direct mass spectrometry (MS) methods are becoming increasingly used for the rapid analysis of food, beverage and agricultural samples. Novel ionization approaches combined with targeted, or untargeted workflows provide analytical outcomes within a greatly reduced time period compared to traditional separation science coupled with ...
Leigh M. Schmidtke, Liang Jiang, Morphy Dumlao, William A. Donald   +3 more
wiley   +1 more source

LKB1–AMPK Signaling Pathway in Cardiovascular and Other Diseases

MedComm, Volume 7, Issue 3, March 2026.
The LKB1–AMPK pathway has a central regulatory role in various diseases. Dysfunction of this pathway can lead to pathological processes in cardiovascular diseases (atrial fibrillation, myocardial infarction, myocardial hypertrophy, atherosclerosis), metabolic diseases (diabetes and kidney disease), neurodegenerative diseases (Alzheimer's disease ...
Zhuo Chen, Qin Yang, Guo‐Wei He
wiley   +1 more source

Protein Lactylation in Cancer: Mechanisms and Therapeutic Targets

MedComm, Volume 7, Issue 3, March 2026.
This schematic illustrates the central role of lactylation, a lactate‐derived posttranslational modification, in linking metabolic reprogramming to cancer progression and therapy resistance. At its core, lactylation modulates proteins, influenced by metabolic shifts and environmental factors.
Qianying Ouyang, Qianyu Hu, Caiqin Wang, Yizi He, Ruolan Zeng, Yajun Li, Chang Su, Guige Lu, Xueting Zhu, Ling Xiao, Hui Zhou   +10 more
wiley   +1 more source