Oxidative stress in DNA repeat expansion disorders: a focus on NRF2 signaling involvement [PDF]
DNA repeat expansion disorders are a group of neuromuscular and neurodegenerative diseases that arise from the inheritance of long tracts of nucleotide repetitions, located in the regulatory region, introns, or inside the coding sequence of a gene ...
Bertini, Enrico Silvio +3 more
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A pharmacokinetic study on red ginseng with furosemide in equine [PDF]
Red ginseng (RG) is a popular ingredient in traditional Korean medicine that has various health benefits. It is commonly taken orally as a dietary supplement; however, its potential interactions with concomitantly administered drugs are unclear.
Ahram Kim +7 more
core +1 more source
How natural therapies can combat neoplastic disease by targeting key survival mechanisms and signaling pathways [PDF]
Plant extracts are increasingly becoming an answer to expensive, high-dose, synthesized chemotherapy, with milder side effects and easier accessibility. Many botanical plants contain active ingredients, such as terpenoids and alkaloids, which may combat ...
Barker, James +11 more
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Obesity is a major health concern and is becoming an increasingly serious societal problem worldwide. The browning of white adipocytes has received considerable attention because of its potential protective effect against obesity-related metabolic ...
Kippeum Lee +6 more
doaj +1 more source
Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases [PDF]
Funding Information: Research in the authors\u2019 laboratories is funded as follows: AIR and AC by the Spanish Ministry of Science, Innovation and Universities (PID2019-110061RB-I00, PID-2021-122766OB-100, PDC2021-121421-I00, PDC2022-133765-I00 ...
Buttari, Brigitta +27 more
core +3 more sources
Waterlogging affects the anti-melanogenic properties of Platycodon grandiflorus roots [PDF]
Waterlogging caused by climate change has threatened the growth and production yield of crops. Although morphological and physiological changes in major crops under waterlogging have been well-defined, the effect of waterlogging on the quality of ...
Hyo Seong Ji, Tae Kyung Hyun
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Gintonin‐Mediated Depolarization of Pacemaker Activity in Cultured Interstitial Cells of Cajal
We investigated the effect of gintonin, a novel ginseng‐derived G protein‐coupled lysophosphatidic acid (LPA) receptor ligand, on the pacemaker activity of the interstitial cells of Cajal (ICC) in murine small intestine and GI motility.
Byung Joo Kim +7 more
openaire +1 more source
Effect of gintonin on matrix metalloproteinase-9 concentration in tears during corneal wound healing in rabbits [PDF]
Ha-Eun Lee +3 more
openalex +1 more source
Rethinking the Use of Antidepressants to Treat Alcohol Use Disorders and Depression Comorbidity: The Role of Neurogenesis [PDF]
Patients with alcohol use disorders (AUDs) are frequently treated with antidepressant drugs (ADs), but clinical evidence of their efficacy is contradictory.
Alén, Francisco +4 more
core +1 more source
Ginseng-Related Drug-Induced Liver Injury [PDF]
Ginseng is commonly used as a medicinal herb for memory and concentration and general well-being. Drug-induced liver injury (DILI) is one of the most challenging disorders and trending events in the United States which are related to body building and ...
Aung Naing Lin +5 more
core +1 more source

