Results 101 to 110 of about 631 (158)

Model organisms for investigating the functional involvement of NRF2 in non-communicable diseases [PDF]

open access: yes
Funding Information: Research in the authors\u2019 laboratories is funded as follows: AIR and AC by the Spanish Ministry of Science, Innovation and Universities (PID2019-110061RB-I00, PID-2021-122766OB-100, PDC2021-121421-I00, PDC2022-133765-I00 ...
Buttari, Brigitta   +27 more
core   +3 more sources

The Gintonin-Enriched Fraction of Ginseng Regulates Lipid Metabolism and Browning via the cAMP-Protein Kinase a Signaling Pathway in Mice White Adipocytes

open access: yesBiomolecules, 2020
Obesity is a major health concern and is becoming an increasingly serious societal problem worldwide. The browning of white adipocytes has received considerable attention because of its potential protective effect against obesity-related metabolic ...
Kippeum Lee   +6 more
doaj   +1 more source

Rethinking the Use of Antidepressants to Treat Alcohol Use Disorders and Depression Comorbidity: The Role of Neurogenesis [PDF]

open access: yes, 2019
Patients with alcohol use disorders (AUDs) are frequently treated with antidepressant drugs (ADs), but clinical evidence of their efficacy is contradictory.
Alén, Francisco   +4 more
core   +1 more source

Gintonin‐Mediated Depolarization of Pacemaker Activity in Cultured Interstitial Cells of Cajal

open access: yesThe FASEB Journal, 2015
We investigated the effect of gintonin, a novel ginseng‐derived G protein‐coupled lysophosphatidic acid (LPA) receptor ligand, on the pacemaker activity of the interstitial cells of Cajal (ICC) in murine small intestine and GI motility.
Byung Joo Kim   +7 more
openaire   +1 more source

Waterlogging affects the anti-melanogenic properties of Platycodon grandiflorus roots [PDF]

open access: yes
Waterlogging caused by climate change has threatened the growth and production yield of crops. Although morphological and physiological changes in major crops under waterlogging have been well-defined, the effect of waterlogging on the quality of ...
Hyo Seong Ji, Tae Kyung Hyun
core   +1 more source

Ginseng-Related Drug-Induced Liver Injury [PDF]

open access: yes, 2018
Ginseng is commonly used as a medicinal herb for memory and concentration and general well-being. Drug-induced liver injury (DILI) is one of the most challenging disorders and trending events in the United States which are related to body building and ...
Aung Naing Lin   +5 more
core   +1 more source

Gintonin modulates platelet function and inhibits thrombus formation via impaired glycoprotein VI signaling

open access: yesPlatelets, 2018
Panax ginseng (P. ginseng), one of the most valuable medicinal plants, is known for its healing and immunobooster properties and has been widely used in folk medicine against cardiovascular diseases, including stroke and heart attack. In this study, we explored the anti-platelet activity of gintonin (a recently discovered non-saponin fraction of ...
Muhammad, Irfan   +10 more
openaire   +2 more sources

Effects of Gintonin-Enriched Fraction in an Atopic Dermatitis Animal Model: Involvement of Autotaxin Regulation

open access: yesBiological & Pharmaceutical Bulletin, 2017
Ginseng extract has been used for prevention of atopic dermatitis (AD) in experimental animal models. However, little is known about its active ingredients and the molecular mechanisms underlying its anti-AD effects. Recently, we isolated a unique lysophosphatidic acid (LPA) receptor ligand, gintonin, from ginseng.
Byung-Hwan, Lee   +9 more
openaire   +3 more sources

Heme oxygenase 1 in the nervous system: Does it favor neuronal cell survival or induce neurodegeneration? [PDF]

open access: yes, 2018
Heme oxygenase 1 (HO-1) up-regulation is recognized as a pivotal mechanism of cell adaptation to stress. Under control of different transcription factors but with a prominent role played by Nrf2, HO-1 induction is crucial also in nervous system response ...
Brondolo, Lorenzo   +5 more
core   +1 more source

An In-Depth Examination of the Pharmacological Effects of Plants in the Therapeutic Management of Alzheimer\u27s Disease. [PDF]

open access: yes
Alzheimer\u27s disease is a progressive neurological condition caused by changes in the brain, leading to memory loss, confusion, emotional instability, and cognitive decline.
Sudhir Kr Mishra
core   +1 more source

Home - About - Disclaimer - Privacy