Platelets, 2018 Panax ginseng (P. ginseng), one of the most valuable medicinal plants, is known for its healing and immunobooster properties and has been widely used in folk medicine against cardiovascular diseases, including stroke and heart attack. In this study, we explored the anti-platelet activity of gintonin (a recently discovered non-saponin fraction of ...
Muhammad, Irfan +10 more
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Biological & Pharmaceutical Bulletin, 2017 Ginseng extract has been used for prevention of atopic dermatitis (AD) in experimental animal models. However, little is known about its active ingredients and the molecular mechanisms underlying its anti-AD effects. Recently, we isolated a unique lysophosphatidic acid (LPA) receptor ligand, gintonin, from ginseng.
Byung-Hwan, Lee +9 more
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Finding evidence of efficacy and safety of ginseng in cognitive functions enhacement : "systematic" review : diploma thesis [PDF]
, 2016 Cilj istraţivanja: Pronaći najbolje dostupne dokaze o sigurnosti i učinkovitosti primjene ginsenga u poboljšanju kognitivnih sposobnosti zdravih ispitanika, ispitanika s blagim kognitivnim oštećenjem ili demencijom.
Leskur, Dario
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Heme oxygenase 1 in the nervous system: Does it favor neuronal cell survival or induce neurodegeneration? [PDF]
, 2018 Heme oxygenase 1 (HO-1) up-regulation is recognized as a pivotal mechanism of cell adaptation to stress. Under control of different transcription factors but with a prominent role played by Nrf2, HO-1 induction is crucial also in nervous system response ...
Brondolo, Lorenzo +5 more
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An In-Depth Examination of the Pharmacological Effects of Plants in the Therapeutic Management of Alzheimer\u27s Disease. [PDF]
Alzheimer\u27s disease is a progressive neurological condition caused by changes in the brain, leading to memory loss, confusion, emotional instability, and cognitive decline.
Sudhir Kr Mishra
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Evolution of the adaptogenic concept from traditional use to medical systems: Pharmacology of stress- and aging-related diseases [PDF]
, 2020 Adaptogens comprise a category of herbal medicinal and nutritional products promoting adaptability, resilience, and survival of living organisms in stress. The aim of this review was to summarize the growing knowledge about common adaptogenic plants used
Banerjee, S +10 more
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Preparation of a Monoclonal Antibody against Gintonin and Its Use in an Enzyme Immunoassay
Biological & Pharmaceutical Bulletin, 2015 Gintonin is a novel ginseng-derived G protein-coupled lysophosphatidic acid (LPA) receptor ligand. Gintonin elicits an [Ca(2+)]i transient in animal cells via activation of LPA receptors. In vitro studies have shown that gintonin regulates various calcium-dependent ion channels and receptors.
Byung-Hwan, Lee +9 more
openaire +3 more sources
The impact of the administration of red ginseng (Panax ginseng) on lipid metabolism and free fatty acid profiles in healthy horses using a molecular networking approach [PDF]
This study investigated the potential benefits of the administration of red ginseng (RG) on lipid metabolism and the profiles of individual free fatty acids (FFAs) in healthy horses.
Hye Hyun Yoo +2 more
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Clinically proven natural products in aid of treating Parkinson\u27s disease: a comprehensive review [PDF]
Parkinson\u27s disease (PD) is a neurodegenerative disorder that is caused by degeneration of nerve cells in the part of the brain called the substantia nigra, which controls movement.
Ansari, Farzana +9 more
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Effects of Ca2+-Activated Cl- Channel ANO1inhibitors on Pacemaker Activity in Interstitial Cells of Cajal [PDF]
, 2018 Background/Aims: Anoctamin1 (Ca2+-activated Cl- channel, ANO1) is a specific marker of the interstitial cells of Cajal (ICC) in the gastrointestinal tract, and are candidate proteins that can function as pacemaker channels. Recently, novel selective ANO1
Chansik Hong +6 more
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