Results 181 to 190 of about 10,013 (222)

Global but not myeloid lineage-directed Girk3 deletion increases bone mass in female mice. [PDF]

JBMR Plus
Weaver SR, Doolittle ML, Durdan MM, Narum AK, Weivoda MM, Alhamad DW, McGee-Lawrence ME, Khosla S, Taylor EL, Bradley EW, Fernandez de Velasco EM, Wickman K, Westendorf JJ.   +12 more
europepmc   +1 more source

Role of Ion Channels in Alzheimer's Disease Pathophysiology. [PDF]

J Membr Biol
Bhoi R, Mitra T, Tejaswi K, Manoj V, Ghatak S.   +4 more
europepmc   +1 more source

Molecular contacts in self-assembling clusters of membrane proteins. [PDF]

Proc Natl Acad Sci U S A
Mandala VS, Fu Z, MacKinnon R.
europepmc   +1 more source

Intrinsic and synaptic regulation of axonal excitability in dopaminergic neurons. [PDF]

Front Cell Neurosci
Seddon J, Kramer PF.
europepmc   +1 more source

Gamma-Aminobutyric Acid (GABA) as a Dietary Strategy for Enhancing Temperature Stress Resilience in Aquaculture Species. [PDF]

Int J Mol Sci
Ogun AO, Moniruzzaman M, Jeon H, Kim H, Aulia D, Hur J, Yoon S, Lee S, Min T, Lee S.   +9 more
europepmc   +1 more source

GABAB receptor-mediated modulation of sensory neuron excitability: Roles of CaV2.2, G-protein-coupled inwardly rectifying potassium (GIRK) channels, and hyperpolarisation-activated cyclic nucleotide-gated (HCN) channels in human and mouse nociception.

Experimental Physiology, EarlyView.
Chronic visceral pain is a key symptom of irritable bowel syndrome. Modulation of voltage-gated calcium and potassium channels by G protein-coupled receptors plays a key role in dampening nociceptive transmission.
Mariana Brizuela, Anuja R. Bony, S. Garcia-Caraballo, David J. Adams, Stuart M. Brierley   +4 more
semanticscholar   +2 more sources

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Co‐activation of GPCRs facilitate GIRK‐dependent current

The Journal of Physiology, 2022
The activity of dopamine neurons is dependent on both intrinsic properties and afferent projections. One potent form of inhibition is mediated by the activation of two inhibitory G protein‐coupled receptors, D2 and GABAB receptors.
Alec F. Condon, Naeem Asad, Timothy M. Dore, John T. Williams   +3 more
semanticscholar   +3 more sources

Leptin excites basolateral amygdala principal neurons and reduces food intake by LepRb‐JAK2‐PI3K‐dependent depression of GIRK channels

Journal of Cellular Physiology, 2023
Leptin is an adipocyte‐derived hormone that modulates food intake, energy balance, neuroendocrine status, thermogenesis, and cognition. Whereas a high density of leptin receptors has been detected in the basolateral amygdala (BLA) neurons, the ...
Cody A Boyle, P. K. Kola, C. S. Oraegbuna, S. Lei   +3 more
semanticscholar   +1 more source