Results 51 to 60 of about 1,496,082 (264)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
New family of simple $\mathfrak{gl}_{2n}(\mathbb{C})$-modules
, 2015 We construct a new family of simple $\mathfrak{gl}_{2n}$-modules which depends on $n^2$ generic parameters. Each such module is isomorphic to the regular $U(\mathfrak{gl}_{n})$-module when restricted the $\mathfrak{gl}_{n}$-subalgebra naturally embedded ...
Nilsson, Jonathan
core +1 more source
Molecular Oncology, EarlyView.The LINC01116 long noncoding RNA is induced by hypoxia and associated with poor prognosis and high recurrence rates in two cohorts of lung adenocarcinoma patients. Here, we demonstrate that besides its expression in cancer cells, LINC01116 is markedly expressed in lymphatic endothelial cells of the tumor stroma in which it participates in hypoxia ...
Marine Gautier‐Isola +12 more
wiley +1 more source
On Using Grey Literature and Google Scholar in Systematic Literature Reviews in Software Engineering
IEEE Access, 2020 Context: The inclusion of grey literature (GL) is important to remove publication bias while gathering available evidence regarding a certain topic. The number of systematic literature reviews (SLRs) in Software Engineering (SE) is increasing but we do ...
Affan Yasin +5 more
doaj +1 more source
Reply to Comment by E. Babaev and M. Silaev, arXiv:1105.3756
, 2011 The criticism of Babaev and Silaev notwithstanding, we conclude that our analysis is correct. We have found in our papers on two-band superconductors close to Tc, where the Ginzburg-Landau (GL) theory applies, that these materials are characterized by a ...
Kogan, V. G., Schmalian, Joerg
core +1 more source
Therapeutic strategies for MMAE‐resistant bladder cancer through DPP4 inhibition
Molecular Oncology, EarlyView.We established monomethyl auristatin E (MMAE)‐resistant bladder cancer (BC) cell lines by exposure to progressively increasing concentrations of MMAE in vitro. RNA sequencing showed DPP4 expression was increased in MMAE‐resistant BC cells. Both si‐DPP4 and the DPP4 inhibitor sitagliptin suppressed the viability of MMAE‐resistant BC cells.
Gang Li +10 more
wiley +1 more source
Molecular Oncology, EarlyView.Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang +3 more
wiley +1 more source
Assessing the potential of Moldova’s agri-food products in the context of EU neighbourhood
Agricultural Science, 2014 Due to the Deep and Comprehensive Free Trade Agreement signed recently between Moldova and European Union, it is of vital importance for local agri-food products to be competitive on the EU market in order to benefit from the potential gains of the ...
CIMPOIEŞ Liliana , COŞER Cornel
doaj
Ecosphere, 2017 Invasive alien species (IAS) are species whose introduction or spread outside their native range threatens biological diversity, ecosystem functioning, economy, and/or public health.
J. Matthews +6 more
doaj +1 more source
Molecular Oncology, EarlyView.Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee +8 more
wiley +1 more source