Results 61 to 70 of about 304,609 (284)
We established the avian chorioallantoic membrane (CAM) assay as a scalable in vivo model for studying circulating tumor cells (CTCs). Human gastrointestinal tumors spontaneously released genetically validated CTCs that were detected across multiple platforms, demonstrating that the CAM model provides an accessible tool for investigating early cancer ...
Dennis Roth +17 more
wiley +1 more source
Appendix: The GL(n) pack Manual [PDF]
This appendix is the manual for a set of functions written to assist the reader to understand and apply the theorems on GL(n, R) set out in the main part of the book.
Broughan, Kevin A.
core
Cyber-Physical Systems (CPSs) represent a systems category developed and promoted in the maritime industry to automate functions and system operations.
Victor Bolbot +4 more
doaj +1 more source
Derivatives for smooth representations of GL(n, ℝ) and GL(n, ℂ) [PDF]
The notion of derivatives for smooth representations of GL(n) in the p-adic case was defined by J. Bernstein and A. Zelevinsky. In the archimedean case, an analog of the highest derivative was defined for irreducible unitary representations by S. Sahi and called the "adduced" representation.
Aizenbud, A., Gourevitch, D., Sahi, S.
openaire +3 more sources
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim +17 more
wiley +1 more source
The Event Horizon Telescope (EHT) has recently released high-resolution images of accretion flows onto two supermassive black holes. Our physical understanding of these images depends on the accuracy and precision of numerical models of plasma and ...
Monika A. Moscibrodzka +1 more
doaj +1 more source
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya +2 more
wiley +1 more source
To b(gl) or not to b(gl): how cryptic are “cryptic” genes? [PDF]
A striking feature that has emerged from the genome sequencing projects that have been completed so far is the extremely high coding percentage seen in all bacterial genomes. In the case of Escherichia coli, it is higher than 90% (in higher eukaryotes including humans, it can be as low as 2%). Despite running such a tight ship, many prokaryotic genomes
openaire +2 more sources
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks +4 more
wiley +1 more source
Background Previous epidemiological investigations of associations between dietary glycemic intake and insulin resistance have used average daily measures of glycemic index (GI) and glycemic load (GL).
O'Neill Sheila +3 more
doaj +1 more source

