Results 131 to 140 of about 36,882 (280)

Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies

open access: yesAngewandte Chemie, Volume 138, Issue 41, 5 October 2026.
A 310‐helix‐mediated conformational switch promotes a front‐face SNi‐like catalysis by human A4GALT. Mechanism‐guided design identifies AdaGalCer as a selective modulator of globotriaosylceramide (Gb3) biosynthesis, opening a clear route toward new Fabry disease therapeutics.
Nicky de Koster   +13 more
wiley   +2 more sources

Proteomic signatures of equine dental tooth tissues in ageing and disease

open access: yesEquine Veterinary Journal, Volume 58, Issue 6, Page 1552-1569, November 2026.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen   +8 more
wiley   +1 more source

Enhancement of Nutritional Value of Cereals with λ-Linolenic Acid by Fungal Solid-State Fermentations

open access: yesFood Technology and Biotechnology, 2006
The capability of lower filamentous fungi to utilize and to enrich cereals with -linolenic acid (GLA) by solid state fermentation was investigated. Thamnidium elegans was selected as a production strain and a variety of cereal materials were tested with
Lucia Sláviková   +3 more
doaj  

Gla (Γκλα, aujourd'hui "Αρνη)

open access: yes, 1959
Daux Georges. Gla (Γκλα, aujourd'hui "Αρνη). In: Bulletin de correspondance hellénique. Volume 83, livraison 2, 1959.
Daux, Georges
core  

Revisiting Inherited Metabolic Diseases (IMDs) Through the Lens of Selective Autophagy

open access: yesJournal of Inherited Metabolic Disease, Volume 49, Issue 6, November 2026.
ABSTRACT Selective autophagy is increasingly recognized as a fundamental quality‐control mechanism that complements bulk autophagy by enabling the targeted degradation of specific intracellular cargos, including mitochondria, endoplasmic reticulum (ER), lipid droplets, glycogen, peroxisomes, ferritin, ribosomes, and protein aggregates.
Marianna Maddaluno   +3 more
wiley   +1 more source

Gla, Γκλα (aujourd'hui Αρνη)

open access: yes, 1960
Daux Georges. Gla, Γκλα (aujourd'hui Αρνη). In: Bulletin de correspondance hellénique. Volume 84, livraison 2, 1960.
Daux, Georges
core  

Should equine practitioners still prescribe chloramphenicol for treating horses?

open access: yesEquine Veterinary Education, Volume 38, Issue 11, Page e901-e909, November 2026.
Summary Background Clinical breakpoints for chloramphenicol are not currently available to test susceptibility of bacteria isolated from horses. Without these breakpoints, testing the susceptibility of bacterial isolates from horses cannot be interpreted properly.
M. G. Papich   +2 more
wiley   +1 more source

Automated Phenotyping Unveils Trait‐Specific Genotypic Variation in Arbuscular Mycorrhiza Responsiveness in Maize (Zea mays)

open access: yesPlant, Cell &Environment, Volume 49, Issue 11, Page 7957-7975, November 2026.
ABSTRACT Arbuscular mycorrhiza (AM), a symbiosis between land plants and fungi that enhances plant mineral nutrition, has potential for application in sustainable agriculture. The extent to which plants benefit from the symbiosis depends on the plant‐fungal genotype combination, providing opportunities for breeding symbiosis‐optimized crops.
Florian Berger   +7 more
wiley   +1 more source

Trichomes in Plant Defence, Development and Metabolic Integration Under Environmental Stress

open access: yesPlant, Cell &Environment, Volume 49, Issue 11, Page 8437-8453, November 2026.
ABSTRACT Among various plant defence strategies, trichomes are tiny hair‐like structures on the epidermis that aid in defence, environmental adaptation and the production of valuable secondary metabolites. This review features trichomes as frontline guards for plant survival, integrating their structural, physiological and metabolic roles in ...
Debdatta Chatterjee   +5 more
wiley   +1 more source

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