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Transcriptional profile of Glaesserella parasuis in swine serosal and joint fluids [PDF]

Frontiers in Veterinary Science
Glaesserella parasuis is the causative agent of Glässer's disease and contributes to significant post-weaning mortality in the swine industry. Glässer's disease is characterized by meningitis, polyserositis, and polyarthritis.
Daniel W. Nielsen, Kaitlyn M. Sarlo Davila, Susan L. Brockmeier, Samantha J. Hau   +3 more
doaj   +5 more sources

Pig nasal and rectal microbiotas are involved in the antibody response to Glaesserella parasuis. [PDF]

Sci Rep
Vaccination stands as one of the most sustainable and promising strategies to control infectious diseases in animal production. Nevertheless, the causes for antibody response variation among individuals are poorly understood.
Obregon-Gutierrez P, Mahmmod Y, Barba-Vidal E, Sibila M, Correa-Fiz F, Aragón V.   +5 more
europepmc   +9 more sources

Glaesserella parasuis ClpX participates in stress tolerance and contributes to bacterial pathogenicity [PDF]

Microbiology Spectrum
The ClpX gene in bacteria, which plays a key role in adaptation to various environmental stresses, is associated with pathogenicity. However, its role in conferring external environmental stress resistance in Glaesserella parasuis remains unclear.
Manman Xu, Youqiao Fang, Bohong Li, Wenbin Wei, Zesong Wang, Qi Cao, Chen Tan, Ruicheng Yang, Huanchun Chen, Xiangru Wang   +9 more
doaj   +5 more sources

Cytolethal distending toxin from Glaesserella parasuis induces ferroptosis in porcine alveolar macrophages and mice [PDF]

Veterinary Research
Glaesserella parasuis cytolethal distending toxin (GpCDT) is a bacterial genotoxin whose main action is to activate DNA damage responses, induce cell cycle arrest, and induce the apoptosis of host cells.
Shiyu Xu, Li Lei, Zhen Yang, Yu Wang, Senyan Du, Qin Zhao, Xiaobo Huang, Sanjie Cao, Rui Wu, Yiping Wang, Qigui Yan, Yiping Wen   +11 more
doaj   +5 more sources

Antibacterial effects of cinnamaldehyde and hesperitin on resistant Glaesserella parasuis by suppressing QseBC two-component system [PDF]

BMC Veterinary Research
Background Glaesserella parasuis (G. parasuis) is one of the most important porcine pathogens causing Glässer’s disease, and QseBC two-component system (TCS) is associated with various behaviors of G. parasuis.
Jingru Zuo, Lin Liao, Yujun Gao, Junlin Chen, Jiang Teng, Weihua Zhang, Yuhang Wang, Yu Sun, Xiaoqiang Liu   +8 more
doaj   +3 more sources

LncRNA MEG3 Regulates Glaesserella parasuis-Induced Apoptosis of Porcine Alveolar Macrophages via Regulating ssc-miR-135/CASP8 Axis [PDF]

Microorganisms
Glaesserella parasuis (G. parasuis), a common pathogenic bacterium in the porcine respiratory tract, can cause porcine polyserositis, arthritis, and meningitis.
Yongchao Jia, Meiling Qian, Xinlu Sun, Ronglan Yin, Na Li, Aobo Shen, Haoran Wang, Fanhua Zeng, Yuanyuan Zhou, Ronghuan Yin   +9 more
doaj   +3 more sources

Baicalin Relieves Glaesserella parasuis-Triggered Immunosuppression Through Polarization via MIF/CD74 Signaling Pathway in Piglets [PDF]

Biomolecules
Glaesserella parasuis (G. parasuis) infection is responsible for Glässer’s disease in pigs. G. parasuis could trigger piglet immunosuppression, but the mechanism of inducing immunosuppression by G. parasuis remains unknown.
Shulin Fu, Qiaoli Dong, Yunjian Fu, Ronghui Luo, Jingyang Li, Yamin Sun, Siyu Liu, Yinsheng Qiu, Ling Guo, Jin Hu   +9 more
doaj   +3 more sources

A novel function of RHOA as a host-dependent factor in Glaesserella parasuis infection of LLC-PK1 cells [PDF]

Veterinary Research
Glaesserella parasuis (G. parasuis), a lethal pathogen causing Glässer’s disease, poses severe threats to global swine health. While the small GTPase Ras homolog gene family member A (RHOA) is implicated in viral pathogenesis, its role in bacterial ...
Huanhuan Zhou, Xuexue Chen, Xinqi Zeng, Shengsong Xie, Xiaoyu Zhang, Jiayi Zeng, Ke Xu, Bo Yu, Hailong Liu, Hongbo Chen   +9 more
doaj   +3 more sources

Development and application of a dual LAMP-LFD assay for the simultaneous detection of <i>Streptococcus suis</i> and <i>Glaesserella parasuis</i>. [PDF]

Front Cell Infect Microbiol
IntroductionStreptococcus suis (S. suis) and Glaesserella parasuis (G. parasuis) are prevalent pathogens in pig populations and are often associated with co-infections, leading to substantial economic losses in the swine industry.
Wang H, Dong C, Tian X, Pan Y, Wang L, An T, Zhu L.   +6 more
europepmc   +4 more sources

Combined transcriptome and metabolome analysis reveals the regulatory network of histidine kinase QseC in the two-component system of <i>Glaesserella parasuis</i>. [PDF]

Front Microbiol
IntroductionGlaesserella parasuis (G. parasuis) causes agent Glässer’s disease in swine. This study investigated the mechanism of QseC in G. parasuis.MethodsThe study utilized transcriptomic and metabolomic sequencing techniques.
Yan X, Zhou Y, Liu S, Gu C, Xiao W, Zhao M, Yu Z, He L.   +7 more
europepmc   +4 more sources