Results 91 to 100 of about 2,719 (158)

Surface-exposed loops L7 and L8 of Haemophilus (Glaesserella) parasuis OmpP2 contribute to the expression of proinflammatory cytokines in porcine alveolar macrophages [PDF]

, 2019
International audienceOuter membrane protein P2 (OmpP2) of the virulent Haemophilus (Glaesserella) parasuis has been shown to induce the release of proinflammatory cytokines. The OmpP2 protein is composed of eight or nine surface-exposed loops, but it is
Feng, Saixiang, He, Xinyi, Tang, Cheng, Wang, Yuanwei, Yue, Hua, Zhang, Bin, Zhou, Qun, Zhou, Ye   +7 more
core   +1 more source

Baicalin inhibited PANX-1/P2Y6 signaling pathway activation in porcine aortic vascular endothelial cells infected by Glaesserella parasuis

Heliyon
Glaesserella parasuis can induce endothelial barrier damage in piglets, although the mechanism by which this pathogen triggers inflammatory damage remains unclear. Baicalin possesses anti-inflammatory and anti-oxidant activities.
Shulin Fu, Xinyue Tian, Chun Peng, Dan Zhang, Linglu Zhou, Yuzhen Yuan, Jing He, Ling Guo, Yinsheng Qiu, Chun Ye, Yu Liu, Bingbing Zong   +11 more
doaj   +1 more source

Severe Inflammation Caused by Coinfection of PCV2 and Glaesserella parasuis Is Associated with Pyroptosis via Noncanonical Inflammasome Pathway

Cellular Microbiology, 2022
Coinfections of porcine circovirus type 2 (PCV2) and Glaesserella parasuis (G. parasuis) are widely existing in the swine industry worldwide. However, the mechanisms for this coinfection remain unclear.
Jiahui An, Chao Zhang, Jinshuang Cai, Yufeng Li   +3 more
doaj   +1 more source

Deletion of Polyamine Transport Protein PotD Exacerbates Virulence in Glaesserella (Haemophilus) parasuis in the Form of Non-biofilm-generated Bacteria in a Murine Acute Infection Model

Virulence, 2021
Polyamines are small, polycationic molecules with a hydrocarbon backbone and multiple amino groups required for optimal cell growth. The potD gene, belonging to the ABC (ATP-binding cassette) transport system potABCD, encodes the bacterial substrate ...
Ke Dai, Zhen Yang, Xiaoyu Ma, Yung-Fu Chang, Sanjie Cao, Qin Zhao, Xiaobo Huang, Rui Wu, Yong Huang, Jing Xia, Qigui Yan, Xinfeng Han, Xiaoping Ma, Xintian Wen, Yiping Wen   +14 more
doaj   +1 more source

TbpBY167A-Based Vaccine Can Protect Pigs against Glässer’s Disease Triggered by Glaesserella parasuis SV7 Expressing TbpB Cluster I [PDF]

Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0 ...
Chaudhuri, Somshukla, Frandoloso, Rafael, Guizzo, João Antônio, Gutiérrez Martín, César Bernardo, Klein, Rafaela, Kreutz, Luiz Carlos, Paraboni Frandoloso, Gabriela, Ramos Prigol, Simone, Schryvers, Anthony Bernard   +8 more
core   +1 more source

Evolutionary Origins and Virulence Determinants of ST25 Hypervirulent Klebsiella pneumoniae in Swine: Genomic Insights and Functional Validation

Transboundary and Emerging Diseases, Volume 2026, Issue 1, 2026.
The global spread of multidrug‐resistant hypervirulent Klebsiella pneumoniae (MDR‐HvKp), among which carbapenem‐resistant strains are of major concern, poses a severe threat to public health due to its high mortality rate and extremely limited treatment options.
Zheng Chen, Yang Liu, Congyang Du, Shengguo Gao, Lufeng Zhai, Stefan Schwarz, Weicheng Liu, Qiong Li, Longyu Li, Runhao Yu, Yuzhe Zhao, Hong Yao, Lei Luo, Xue Liu, Chunyan Xu, Xiang-Dang Du, Zongfu Wu   +16 more
wiley   +1 more source

ICEHpsaHPS7, a Novel Multiple Drug Resistance Integrative Conjugative Element in Glaesserella parasuis

Antimicrobial Agents and Chemotherapy, 2021
Integrative conjugative elements (ICEs) are a kind of novel self-transmissible mobile genetic element. In this study, a novel ICE was identified in Glaesserella ( Haemophilus ) parasuis .
Jiahui An, Genglin Guo, Dong Yu, Kexin Zhu, Chao Zhang, Yufeng Li   +5 more
openaire   +3 more sources

TbpBY167A-based vaccine is safe in pregnant sows and induces high titers of maternal derived antibodies that reduce Glaesserella parasuis colonization in piglets [PDF]

[EN] Glässer’s disease is one of the main diseases affecting young piglets, particularly during the nursery phase, that can significantly impact pork production.
Dazzi, Cláudia Cerutti, Dellagostin, Diego, Frandaloso, Rafael, Giacobbo, Igor, Guizzo, João Antônio, Gutiérrez Martín, César Bernardo, Klein, Rafaela, Kreutz, Luiz Carlos, Ramos Prigol, Simone, Schryvers, Anthony Bernard   +9 more
core   +1 more source

Characterization of Pilin A and Thioredoxin A Mutant Strains of Acinetobacter baumannii, From a Transposon Insertion Library, for Pili Production and Virulence‐Associated Properties

MicrobiologyOpen, Volume 14, Issue 6, December 2025.
Acinetobacter baumannii transposon insertion mutant strains ΔpilA and ΔtrxA display marked reductions of surface pili. The PilA (a major pilin protein) and TrxA (thioredoxin A) deficient bacteria also show attenuation in pathogenesis including the reduction of intestinal bacterial attachment, increased phagocytic uptake and decreased mortality from ...
Jadelynn Aki, Sara B. Papp, Bayley Polk, Sean Jeffreys, Megan P. Tompkins, Anwar A. Kalalah, Mark Eppinger, Guoquan Zhang, M. N. Guentzel, James P. Chambers, Bernard P. Arulanandam, Jieh‐Juen Yu   +11 more
wiley   +1 more source

Rapid and simple detection of Glaesserella parasuis in synovial fluid by recombinase polymerase amplification and lateral flow strip

BMC Veterinary Research, 2019
Background Glaesserella parasuis (G. parasuis) is an influential pathogen of the pig, which induces high morbidity and mortality in naive pig populations in the pig industry. Accurate and rapid detection of the agent is important for disease control.
Ting-ting Zhang, Meng-zhi Liu, Rong-huan Yin, Long-quan Yao, Bao-shan Liu, Ze-liang Chen   +5 more
doaj   +1 more source