Results 21 to 30 of about 20,787 (190)

The effect of concomitant DPPIVi use on glycaemic control and hypoglycaemia with insulin glargine 300 U/mL (Gla-300) versus insulin glargine 100 U/mL (Gla-100) in people with type 2 diabetes: A patient-level meta-analysis of EDITION 2 and 3 [PDF]

, 2018
Aims To evaluate the effect of concomitant dipeptidyl peptidase IV inhibitor (DPPIVi) use on efficacy and safety of insulin glargine 300 U/mL (Gla-300) versus glargine 100 U/mL (Gla-100) in people with type 2 diabetes on oral antihyperglycaemic drugs ...
Brito-Sanfiel, Miguel, Buzzetti, Raffaella, Chevalier, Soazig, Lavalle-Gonzalez, Fernando, Merino-Trigo, Ana, Pettus, Jeremy Hodson, Stella, Peter, Yale, Jean-François   +7 more
core   +4 more sources

Comparison of insulin detemir and insulin glargine in a Basal-Bolus regimen, with insulin aspart as the mealtime insulin, in patients with type 1 diabetes: A 52-week, multinational, randomized, open-label, parallel-group, treat-to-target noninferiority trial [PDF]

, 2009
Objective: The primary study objective was to determine whether insulin detemir (detemir) was noninferior to insulin glargine (glargine) as the basal insulin in a basal-bolus regimen, with insulin aspart as the mealtime insulin, in terms of glycemic ...
Albright, Bolli, Bruce Bode, Buse, Christoph Koenen, Devries, Garg, Havelund, Heinemann, Heinemann, Heise, Heise, Hermansen, Hougaard, Jehle, Klein, Le Floch, Montgomery, Owens, Pieber, Ratner, Russell-Jones, Simon Heller   +22 more
core   +1 more source

Spotlight commentary-Insulin therapy: Future directions. [PDF]

Br J Clin Pharmacol
British Journal of Clinical Pharmacology, Volume 92, Issue 2, Page 351-353, February 2026.
Deškin A, Cifrek K, Stričak LM, Hladnik A, Barilar JO.   +4 more
europepmc   +2 more sources

Increasing the production of insulin glargine in Pichia pastoris through medium modification [PDF]

BIO Web of Conferences
Insulin is the primary drug for managing diabetes mellitus, especially for individuals with type 1 diabetes mellitus. Producing insulin glargine, a long-acting insulin analogue, using Pichia pastoris is a notable advancement in biopharmaceutical ...
Hardianto Dudi, Safarrida Anna, Prayoga Gilang Surya, Ananda Zr Yufva Pramudia, Munirah, Martius Efrida, Royani Juwartina Ida, Hartuti Endah Dwi   +7 more
doaj   +1 more source

Medication utilization patterns among type 2 diabetes patients initiating Exenatide BID or insulin glargine: a retrospective database study [PDF]

, 2013
BACKGROUND: Type 2 diabetes is a common and costly illness, associated with significant morbidity and mortality. Despite this, there is relatively little information on the ‘real-world’ medication utilization patterns for patients with type 2 diabetes ...
Barbara Johnson, Byron Hoogwerf, Gregory Lenhart, Machaon Bonafede, Manjiri Pawaskar, Robert Fowler   +5 more
core   +1 more source

Continued efforts to translate diabetes cardiovascular outcome trials into clinical practice [PDF]

, 2016
Diabetic patients suffer from a high rate of cardiovascular events and such risk increases with HbA1c. However, lowering HbA1c does not appear to yield the same benefit on macrovascular endpoints, as observed for microvascular endpoints. As the number of
Avogaro, Angelo, Bonora, Enzo, Fadini, GIAN PAOLO, Prato, Stefano Del, Sesti, Giorgio   +4 more
core   +3 more sources

Insulin therapy and dietary adjustments to normalize glycemia and prevent nocturnal hypoglycemia after evening exercise in type 1 diabetes: a randomized controlled trial [PDF]

, 2014
Introduction Evening-time exercise is a frequent cause of severe hypoglycemia in type 1 diabetes, fear of which deters participation in regular exercise.
Campbell, Matthew, Walker, Mark, Bracken, Richard, Turner, David, Stevenson, Emma, Gonzalez, Javier, Shaw, James, West, Dan   +7 more
core   +4 more sources

Treatment satisfaction and psychological well-being with insulin glargine compared with NPH in patients with Type 1 diabetes [PDF]

, 2001
Aims: To assess satisfaction with treatment and psychological well-being associated with insulin glargine and NPH. Insulin glargine, a new long-acting insulin analogue, provides constant, peakless insulin release following once-daily administration and ...
Bradley, Clare, Stewart, J, Witthaus, E
core   +1 more source

Flexibility in insulin prescription

Indian Journal of Endocrinology and Metabolism, 2016
This communication explores the concept of flexibility, a propos insulin preparations and insulin regimes used in the management of type 2 diabetes.
Sanjay Kalra, Yashdeep Gupta, Ambika Gopalakrishnan Unnikrishnan   +2 more
doaj   +1 more source

Glargine as a Basal Insulin Supplement in Recovering Critically Ill Patients - An In Silico Study [PDF]

, 1993
Tight glycaemic control is now benefiting medical and surgical intensive care patients by reducing complications associated with hyperglycaemia. Once patients leave this intensive care environment, less acute wards do not continue to provide the same ...
Razak, N.N., Lin, J., Chase, J.G., Shaw, G.M., Pretty, C.G., Le Compte, A.J., Suhaimi, F.M., Jamaludin, U.   +7 more
core   +1 more source