Results 251 to 260 of about 118,654 (350)

Implications of coexisting neural antibodies with glial fibrillary acidic protein autoimmunity: a single center retrospective cohort study. [PDF]

BMC Neurol
Wei X, Liu G, Wang D, Jie S, Li B, Wu Y, Pan S, Wang S.   +7 more
europepmc   +1 more source

Temporal dynamics of white matter hyperintensities related to Alzheimer's disease in adults with Down syndrome

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION White matter hyperintensities (WMH) are common in Down syndrome (DS), yet their longitudinal evolution and associations with Alzheimer's disease (AD) remain unclear. METHODS Longitudinal MRI study, including 80 DS adults and 53 euploid controls. WMH were segmented on serial FLAIR using a longitudinal pipeline.
Alejandra O. Morcillo‐Nieto, Mateus Rozalem‐Aranha, Lucia Maure‐Blesa, Íñigo Rodríguez‐Baz, José Enrique Arriola‐Infante, Maria Franquesa‐Mullerat, Sara E. Zsadanyi, Lídia Vaqué‐Alcázar, José Allende Parra, Zili Zhao, Javier Arranz, Laura Videla, Isabel Barroeta, Laura Del Hoyo Soriano, Bessy Benejam, Susana Fernández, Aida Sanjuan Hernandez, Lucia Pertierra, Sandra Giménez, Daniel Alcolea, Olivia Belbin, Alberto Lleó, María Carmona‐Iragui, Juan Fortea, Alexandre Bejanin   +24 more
wiley   +1 more source

Female‐biased astrocytic priming shapes early locus coeruleus vulnerability in an Aβ oligomer milieu

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION The locus coeruleus (LC) is an early site of Alzheimer's disease (AD) pathology, yet the role of brainstem astrocytes in early, sex‐dependent vulnerability remains unclear. METHODS In 2‐ to 3‐month‐old APP/PS1 mice, we combined in vivo proton magnetic resonance spectroscopy (MRS) of the brainstem with region‐resolved molecular ...
Srishti Kushwaha, Rupsa Roy Choudhury, Priyanka Bhat, S. Senthil Kumaran, Smitha Karunakaran   +4 more
wiley   +1 more source

Autoimmune glial fibrillary acidic protein astrocytopathy suspected of intracranial infection: A case report. [PDF]

IDCases
Li W, Lin Y, Xu T, Xilifu M.
europepmc   +1 more source

Targeted blood proteome profiling using NULISAseq identifies a high‐performance biomarker panel for Aβ pathology quantification and staging

Alzheimer's &Dementia, Volume 22, Issue 2, February 2026.
Abstract INTRODUCTION While current blood‐based biomarkers for Alzheimer's disease (AD) are effective for determining amyloid beta (Aβ) pathology positivity/negativity, they are insufficient for quantifying Aβ plaque deposition. METHODS We profiled 325 plasma proteins in a Hong Kong Chinese cohort using the Nucleic Acid Linked Immuno‑Sandwich Assay ...
Wenyue Zheng, Yuanbing Jiang, Hiu Yi Wong, Wan Wa Wong, Lily K. W. Cheng, Elaine Y. L. Cheng, Bonnie W. Y. Wong, Ronnie M. N. Lo, Siu Ki Leung, Fanny C. Ip, Jacqueline K. Y. Yuen, Yat Fung Shea, Wai Ming Wong, Chun Keung Shum, Hok Man Wai, Vincent C. T. Mok, Timothy C. Y. Kwok, Kin Y. Mok, Amanda Heslegrave, John Hardy, Henrik Zetterberg, Amy K. Y. Fu, Nancy Y. Ip   +22 more
wiley   +1 more source

A Mild Case of Autoimmune Glial Fibrillary Acidic Protein Astrocytopathy With Chronic Onset. [PDF]

Cureus
Aohara K, Kurooka K, Nishikawa M, Hasegawa I, Takeda A, Tsuji H, Itoh Y.   +6 more
europepmc   +1 more source

Anatolian ground squirrel (Spermophilus xanthoprymnus) retina: Comparative expression of synaptophysin, NeuN, calbindin‐D28k, parvalbumin, glial fibrillary acidic protein, and Iba‐1 during pre‐hibernation and hibernation

The Anatomical Record, Volume 309, Issue 2, Page 451-470, February 2026.
Abstract Hibernation induces significant molecular and cellular adaptations in the retina to maintain function under reduced metabolic conditions. This study aimed to investigate the expression of neuronal, synaptic, and glial markers in the retina of Spermophilus xanthoprymnus during pre‐hibernation and hibernation periods using immunohistochemical ...
Mehmet Özbek, Feyzullah Beyaz, Mustafa Öztop, Harun Karaca, Ahmet Cabir, Begüm Fatma Kiryar   +5 more
wiley   +1 more source

Glial fibrillary acidic protein in plasma and intraocular fluids and the correlation with cognitive function in patients with vitreoretinal disease. [PDF]

Sci Rep
Ness S, Sampani K, Tuz-Zahra F, Aytan N, Alluri S, Fiorello MG, Chen X, Siegel NH, Alosco ML, Xia W, Tripodis Y, Stein TD, Subramanian ML.   +12 more
europepmc   +1 more source

Engineering a Perfusion Bioreactor System for hiPSC‐Derived Progenitor Co‐Culture Capturing Microglial Features in CNS Development

Biotechnology and Bioengineering, Volume 123, Issue 2, Page 363-378, February 2026.
The authors report the development of a controlled and scalable 3D co‐culture system combining hiPSC‐derived erythromyeloid progenitors and neurospheres within the Ambr® 250 Modular platform operated with a newly designed perfusion system. This model faithfully recapitulates early microglia–neural interactions, enabling progenitor integration ...
Catarina M. Gomes, Inês de Sá, Margarida Delgado, Paula M. Alves, Catarina Brito   +4 more
wiley   +1 more source

Astrocytic-OTUD7B ameliorates murine experimental autoimmune encephalomyelitis by stabilizing glial fibrillary acidic protein and preventing inflammation. [PDF]

Nat Commun
Harit K, Yi W, Jeron A, Schmidt J, Beckervordersandforth R, Wyler E, Manukyan A, Deckert M, Radbruch H, Conrad T, Altmüller J, Landthaler M, Wang X, Nishanth G, Schlüter D.   +14 more
europepmc   +1 more source