Results 31 to 40 of about 118,654 (350)

Protein kinase a distribution differentiates human glioblastoma from brain tissue [PDF]

, 2017
Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to ...
Caretta, Antonio, D\u2019Avella, Domenico, Denaro, Luca, Mucignat-Caretta, Carla   +3 more
core   +2 more sources

Plasma glial fibrillary acidic protein detects Alzheimer pathology and predicts future conversion to Alzheimer dementia in patients with mild cognitive impairment

Alzheimer's Research & Therapy, 2020
Plasma glial fibrillary acidic protein (GFAP) is a marker of astroglial activation and astrocytosis. We assessed the ability of plasma GFAP to detect Alzheimer’s disease (AD) pathology in the form of AD-related amyloid-β (Aβ) pathology and conversion to ...
C. Cicognola, S. Janelidze, Joakim Hertze, H. Zetterberg, K. Blennow, N. Mattsson‐Carlgren, O. Hansson   +6 more
semanticscholar   +1 more source

Accuracy of a rapid glial fibrillary acidic protein/ubiquitin carboxyl‐terminal hydrolase L1 test for the prediction of intracranial injuries on head computed tomography after mild traumatic brain injury

Academic Emergency Medicine, 2021
The objective was to determine the accuracy of a new, rapid blood test combining measurements of both glial fibrillary acidic protein (GFAP) and ubiquitin carboxyl‐terminal hydrolase L1 (UCH‐L1) for predicting acute traumatic intracranial injury (TII) on
J. Bazarian, R. Welch, Krista L. Caudle, Craig A. Jeffrey, James Chen, R. Chandran, Tamara McCaw, S. Datwyler, Hongwei Zhang, B. Mcquiston   +9 more
semanticscholar   +1 more source

Environmental enrichment protects the retina from early diabetic damage in adult rats. [PDF]

PLoS ONE, 2014
Diabetic retinopathy is a leading cause of reduced visual acuity and acquired blindness. Available treatments are not completely effective. We analyzed the effect of environmental enrichment on retinal damage induced by experimental diabetes in adult ...
Damián Dorfman, Marcos L Aranda, María Florencia González Fleitas, Mónica S Chianelli, Diego C Fernandez, Pablo H Sande, Ruth E Rosenstein   +6 more
doaj   +1 more source

Demonstration of astrocytes in cultured amniotic fluid cells of three cases with neural-tube defect [PDF]

, 1981
We have investigated the origin of rapidly adhering (RA) cells in three cases of neural tube defects (two anencephali, one encephalocele). We were able to demonstrate the presence of glial fibrillary acidic (GFA) protein in variable percentages (4–80 ...
AD Smith, AK Buamah, B Nørgaard-Pedersen, CB Laurell, CM Gosden, CM Gosden, CM Gosden, D Bignami, E Crouch, GR Sutherland, LB Chen, LF Eng, LF Eng, M Schachner, M Schachner, M Seppälä, NJ Wald, S Sarkar, T Voigtländer   +18 more
core   +1 more source

Association of Blood Biomarkers With Acute Sport-Related Concussion in Collegiate Athletes: Findings From the NCAA and Department of Defense CARE Consortium [PDF]

, 2020
Importance: There is potential scientific and clinical value in validation of objective biomarkers for sport-related concussion (SRC). Objective: To investigate the association of acute-phase blood biomarker levels with SRC in collegiate athletes.
Broglio, Steven P., Brooks, M. Alison, Cameron, Kenneth L., Campbell, Darren E., CARE Consortium Investigators, DiFiori, Jon, Duma, Stephan, Foroud, Tatiana, Gill, Jessica, Giza, Christopher C., Goldman, Joshua, Guskiewicz, Kevin, Harezlak, Jaroslaw, Houston, Megan N., Huber, Daniel L., Jackson, Jonathan C., Katz, Barry P., McAllister, Thomas W., McCrea, Michael, McGinty, Gerald, Meier, Timothy B., Mihalik, Jason, Nelson, Lindsay D., Pasquina, Paul, Rowson, Steven, Saykin, Andrew J., Svoboda, Steven J.   +26 more
core   +1 more source

Combination of plasma amyloid beta(1-42/1-40) and glial fibrillary acidic protein strongly associates with cerebral amyloid pathology

Alzheimer's Research & Therapy, 2020
Blood-based biomarkers for Alzheimer’s disease (AD) might facilitate identification of participants for clinical trials targeting amyloid beta (Abeta) accumulation, and aid in AD diagnostics.
I. Verberk, Elisabeth H Thijssen, Jannet Koelewijn, Kimberley Mauroo, Jeroen Vanbrabant, Arno de Wilde, M. Zwan, S. Verfaillie, R. Ossenkoppele, F. Barkhof, B. V. van Berckel, P. Scheltens, W. M. van der Flier, E. Stoops, H. Vanderstichele, C. Teunissen   +15 more
semanticscholar   +1 more source

Serum levels of glial fibrillary acidic protein in patients with amyotrophic lateral sclerosis

Annals of Clinical and Translational Neurology, 2022
To compare serum levels of the astrocyte biomarker glial fibrillary acidic protein (GFAP) in patients with amyotrophic lateral sclerosis (ALS) and neurologically healthy controls and to analyze the relations between serum GFAP (sGFAP) and phenotype in ...
F. Verde, Ilaria Milone, A. Maranzano, E. Colombo, Silvia Torre, F. Solca, A. Doretti, Francesco Gentile, Arianna Manini, Ruggero Bonetti, S. Peverelli, S. Messina, L. Maderna, C. Morelli, B. Poletti, A. Ratti, V. Silani, N. Ticozzi   +17 more
semanticscholar   +1 more source

Primary ependymoma of the ovary mimicking as yolk sac tumor: A rare case report

Indian Journal of Medical and Paediatric Oncology, 2020
Ependymoma is a glioma with the differentiation toward ependymal cells that usually arise in the central nervous system. Primary ovarian ependymoma is a rare gynecologic malignancy, of which very few cases have been published.
Trupti S Patel, Satarupa T Samanta, Torsha T Jana, Priti P Trivedi   +3 more
doaj   +1 more source

Clinical Features of Multicenter Autoimmune Glial Fibrillary Acidic Protein Astrocytosis

罕见病研究, 2022
Objective To investigate the clinical features of autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy. Methods We collected and analyzed the clinical and laboratory data and obtained the clinical characteristics of diagnosis and treatment ...
ZHENG Xiujun, LIN Qi, SHU Yaqing, SUN Xiaobo, ZHONG Xiaonan, LI Rui, CHANG Yanyu, QIU Wei, WANG Yuge   +8 more
doaj   +1 more source