Experimental Physiology, EarlyView.Abstract Menopause increases the risk of hypertension in women, yet the factors contributing to this important change remain unclear. Because early life stress has persistent and sex‐specific consequences on health, we hypothesized that ageing reveals the latent effects of neonatal maternal separation (NMS) on cardiovascular homeostasis in female rats.
Danuzia Ambrozio‐Marques +6 more
wiley +1 more source
Genetic and epigenetic analysis of plasma glial fibrillary acidic protein (GFAP) levels in PTSD. [PDF]
Mol PsychiatryMiller MW +5 more
europepmc +1 more source
Glial cells in the heart: Implications for their roles in health and disease
The Journal of Physiology, EarlyView.Abstract figure legend Schematic representation of cardiac autonomic ganglia within epicardial fat pads (posterior heart surface shown), containing vagal postganglionic neuron cell bodies, associated fibres, and glia. These ganglia receive cholinergic input from vagal preganglionic neurons and adrenergic input from sympathetic postganglionic neurons ...
Svetlana Mastitskaya +2 more
wiley +1 more source
Autoimmune glial fibrillary acid protein (GFAP) astrocytopathy
, 2019 Rohit Sharma +2 more
openaire +1 more source
Ultrastructure of astrocytes using volume electron microscopy: A scoping review
The Journal of Physiology, EarlyView.Abstract figure legend A complete overview on astrocyte ultrastructure with volume electron microscopy. The morphology of astrocytes under physiological and pathological conditions plays a role in brain homeostasis, synaptic activity and structural support, but their morphological complexity and heterogeneity are still poorly quantified.
Vanessa Chiappini +7 more
wiley +1 more source
Müller Glial Kir4.1 Channel Dysfunction in APOE4‐KI Model of Alzheimer's Disease
Glia, Volume 74, Issue 3, March 2026.APOE4 impairs Müller cell health by reducing Kir4.1 expression and buffering. APOE4 causes mitochondrial dysfunction with decreased ΔΨm and increased ROS. MitoQ restores Kir4.1 expression and reduces ROS in APOE4‐transfected cells. ABSTRACT Alzheimer's disease (AD), particularly late‐onset AD (LOAD), affects millions worldwide, with the apolipoprotein ...
Surabhi D. Abhyankar +8 more
wiley +1 more source
Blood-brain barrier disruption and perivascular beta-amyloid accumulation in the brain of aged rats with spontaneous hypertension: Evaluation with dynamic contrast-enhanced magnetic resonance imaging [PDF]
, 2018 Chen, Wei +8 more
core +2 more sources
Clinical course and long-term outcomes in autoimmune glial fibrillary acidic protein (GFAP) astrocytopathy. [PDF]
J NeurolArzalluz-Luque J +10 more
europepmc +1 more source
CDC42‐Effector Proteins Regulate Higher Order Structure of Septins Required for CNS Myelin Integrity
Glia, Volume 74, Issue 3, March 2026.CDC42‐effector proteins 1/2 are present in CNS myelin. They facilitate the higher order structure of myelin septin filaments. Their loss impairs septin‐dependent scaffolding of myelin. Myelin outfoldings do not cause secondary neuropathology per se. ABSTRACT The regular structure of CNS myelin requires specialized structural proteins, including septin ...
Sophie Hümmert +14 more
wiley +1 more source
Calponin‐3 is associated with epilepsy through the regulation of astrocyte activity
Brain Pathology, Volume 36, Issue 2, March 2026.Increased calponin‐3 expression correlates with astrocyte activation in epileptic mice, modulating adenosine metabolism regulators ADK and ENT1. Calponin‐3 overexpression increased susceptibility to epileptic seizures, while its downregulation reduces spontaneous recurrent seizures, identifying it as a potential therapeutic target for epilepsy ...
Lu Chen +12 more
wiley +1 more source