Results 31 to 40 of about 82,505 (300)

Phosphorylation of GFAP is associated with injury in the neonatal pig hypoxic-ischemic brain [PDF]

, 2012
Glial fibrillary acidic protein (GFAP) is an intermediate filament protein expressed in the astrocyte cytoskeleton that plays an important role in the structure and function of the cell.
A Lee, BE Lingwood, C Peeters-Scholte, CE Finch, David V. Pow, DM Ferriero, DV Pow, DV Pow, EG Hughes, GA Dienel, H Kosako, H Li, H Tanaka, J Middeldorp, JH Herskowitz, K Morimoto, K Tsujimura, KD Geiger, L Hertz, L Hertz, L Li, LF Eng, LJ Martin, LM Valentim, LT Macnab, M Anderova, M Inagaki, M Inagaki, M Inagaki, M Sekimata, M Takemura, MA Korolainen, MC Toet, MR Cilio, MV Sofroniew, P Lipton, Paul B. Colditz, R Rodnight, Robert K. P. Sullivan, S. Tracey Björkman, SM Sullivan, SM Sullivan, SM Sullivan, SM Sullivan, SM Williams, ST Bjorkman, ST Bjorkman, Stephanie M. Miller, Susan M. Sullivan, SV Sizonenko, T Yano, U Wilhelmsson, Y Matsuoka, Zoe Ireland   +53 more
core   +1 more source

Local industrial pollution induces astrocyte cytoskeleton rearrangement in the dice snake brain: GFAP as a biomarker

Biosystems Diversity, 2020
The present study was designed to evaluate the responsiveness of modulation of glial fibrillary acidic protein (GFAP) content and its fragmentation in the snake brain as a biomarker of local industrial pollution of aquatic ecosystems.
V. Y. Gasso, A. N. Hahut, S. V. Yermolenko, I. A. Hasso, C. A. Agca, E. V. Sukharenko, V. S. Nedzvetsky   +6 more
doaj   +1 more source

Loss of Immunohistochemical Reactivity in Association With Handling-Induced Dark Neurons in Mouse Brains. [PDF]

, 2020
The handling-induced dark neuron is a histological artifact observed in brain samples handled before fixation with aldehydes. To explore associations between dark neurons and immunohistochemical alterations in mouse brains, we examined protein products ...
Chang, Rachel C, Jeste, Dilip V, Patel, Hemal H, Schilling, Jan M, Soontornniyomkij, Benchawanna, Soontornniyomkij, Virawudh   +5 more
core  

Maternal embryonic leucine zipper kinase (MELK) regulates multipotent neural progenitor proliferation. [PDF]

, 2005
Maternal embryonic leucine zipper kinase (MELK) was previously identified in a screen for genes enriched in neural progenitors. Here, we demonstrate expression of MELK by progenitors in developing and adult brain and that MELK serves as a marker for self-
Bajpai, Ruchi, Dougherty, Joseph D, Freije, William A, Geschwind, Daniel H, Groszer, Matthias, Imura, Tetsuya, Kelly, Theresa K, Kim, Kevin J, Kornblum, Harley I, Liu, Xin, Nakano, Ichiro, Nelson, Stanley F, Ou, Jing, Paucar, Andres A, Sofroniew, Michael V, Terskikh, Alexey V, Wu, Hong, Zewail, Amani   +17 more
core   +2 more sources

Combining H-FABP and GFAP increases the capacity to differentiate between CT-positive and CT-negative patients with mild traumatic brain injury [PDF]

, 2018
Mild traumatic brain injury (mTBI) patients may have trauma-induced brain lesions detectable using CT scans. However, most patients will be CT-negative. There is thus a need for an additional tool to detect patients at risk. Single blood biomarkers, such
Bustamante, Alejandro, Egea Guerrero, Juan José, El Rahal, Amir, García-Armengol, Roser, Lagerstedt, Linnéa, Melinda Prica, Carmen, Montaner, Joan, Quintana-Díaz, Manuel, Rodríguez Rodríguez, Ana   +8 more
core   +1 more source

Structural flexibility and heterogeneity of recombinant human glial fibrillary acidic protein (GFAP)

Proteins: Structure, Function, and Bioinformatics, 2023
Glial fibrillary acidic protein (GFAP) is a promising biomarker for brain and spinal cord disorders. Recent studies have highlighted the differences in the reliability of GFAP measurements in different biological matrices. The reason for these discrepancies is poorly understood as our knowledge of the protein’s 3-dimensional conformation, proteoforms ...
Dea Gogishvili, Eva Illes‐Toth, Matthew J. Harris, Christopher Hopley, Charlotte E. Teunissen, Sanne Abeln   +5 more
openaire   +5 more sources

Extracellular vesicle-induced differentiation of neural stem progenitor cells [PDF]

, 2019
Neural stem progenitor cells (NSPCs) from E13.5 mouse embryos can be maintained in culture under proliferating conditions. Upon growth-factor removal, they may differentiate toward either neuronal or glial phenotypes or both.
Biagioni, S., Cacci, E., Cardarelli, S., Conti, R., Poiana, G., Stronati, E.   +5 more
core   +1 more source

Granule Cell Dispersion in Human Temporal Lobe Epilepsy: Proteomics investigation of neurodevelopmental migratory pathways [PDF]

, 2020
Granule cell dispersion (GCD) is a common pathological feature observed in the hippocampus of patients with Mesial Temporal Lobe Epilepsy (MTLE). Pathomechanisms underlying GCD remain to be elucidated, but one hypothesis proposes aberrant reactivation of
Al-Kaaby, B., Al-Kaaby, B., Dzurova, N., Dzurova, N., Liu, J., Liu, J., Millks, K., Millks, K., Sisodiya, S.M., Sisodiya, S.M., Thom, M., Thom, M.   +11 more
core   +1 more source

Serum glial fibrillary acidic protein (GFAP)-antibody in idiopathic intracranial hypertension

International Journal of Neuroscience, 2020
Idiopathic intracranial hypertension (IIH), a disease of obscure origin, is characterized by headache and visual disturbances due to increased intracranial pressure. Recent line of evidence has suggested involvement of inflammation in IIH pathogenesis thus bringing forward anti-glial autoimmunity as a potential contributor of IIH.
Berrak Yetimler, John Tzartos, Büşra Şengül, Erdinç Dursun, Çağrı Ulukan, Katerina Karagiorgou, Duygu Gezen-Ak, Mine Sezgin, Aliki Papaconstantinou, Socrates Tzartos, Elif Kocasoy Orhan, Esme Ekizoğlu, Cem İsmail Küçükali, Betül Baykan, Erdem Tüzün   +14 more
openaire   +3 more sources

Characterization of the transient middle cerebral artery occlusion model of ischemic stroke in a HuR transgenic mouse line

Data in Brief, 2018
This set of experiments characterizes a model of transient cerebral ischemic stroke in a transgenic (Tg) mouse line in which the glial fibrillary acidic protein (GFAP) promoter is utilized to drive expression of a human RNA-binding protein, HuR ...
A. Ardelt, R. Carpenter, I. Iwuchukwu, A. Zhang, W. Lin, E. Kosciuczuk, C. Hinkson, T. Rebeiz, S. Reitz, P. King   +9 more
doaj   +1 more source