Results 11 to 20 of about 319,103 (346)

Epidemiology of Glioblastoma Multiforme–Literature Review

Cancers, 2022
Simple Summary Glioblastoma multiforme (GBM) is one of the most aggressive malignancies, accounting for 14.5% of all central nervous system tumors and 48.6% of malignant central nervous system tumors.
S. Grochans, A. Cybulska, Donata Simińska, J. Korbecki, K. Kojder, D. Chlubek, I. Baranowska-Bosiacka   +6 more
semanticscholar   +1 more source

Phase III trial of chemoradiotherapy with temozolomide plus nivolumab or placebo for newly diagnosed glioblastoma with methylated MGMT promoter

Neuro-Oncology, 2022
Background Nearly all patients with newly diagnosed glioblastoma experience recurrence following standard-of-care radiotherapy (RT) + temozolomide (TMZ).
M. Lim, M. Weller, A. Idbaih, J. Steinbach, G. Finocchiaro, R. Raval, G. Ansstas, J. Baehring, Jennie W. Taylor, J. Honnorat, K. Petrecca, F. D. De Vos, A. Wick, A. Sumrall, S. Sahebjam, I. Mellinghoff, M. Kinoshita, M. Roberts, R. Slepetis, D. Warad, D. Leung, Michelle Lee, D. Reardon, A. Omuro   +23 more
semanticscholar   +1 more source

Emerging therapies for glioblastoma: current state and future directions

Journal of experimental & clinical cancer research : CR, 2022
Glioblastoma (GBM) is the most common high-grade primary malignant brain tumor with an extremely poor prognosis. Given the poor survival with currently approved treatments for GBM, new therapeutic strategies are urgently needed.
Liang Rong, Ni Li, Zhenzhen Zhang
semanticscholar   +1 more source

Tectal glioblastoma [PDF]

Arquivos de Neuro-Psiquiatria, 2007
Brain stem gliomas are a heterogeneous group of neoplasms arising mostly in paediatric patients. Tectal plate gliomas represent a particular type of brain stem tumours usually with a benign, indolent clinical course, presenting with signs of raised intracranial hipertension due to supra-tentorialhydrocephalous caused by aqueductal stenosis. Seldom high-
Chaddad Neto, Feres, Lopes, Armando, Alberto Filho, Mario, Catanoce, Aguinaldo, Joaquim, Andrei Fernandes, Oliveira, Evandro de   +5 more
openaire   +4 more sources

Recent Developments in Glioblastoma Therapy: Oncolytic Viruses and Emerging Future Strategies

Viruses, 2023
Glioblastoma is the most aggressive form of malignant brain tumor. Standard treatment protocols and traditional immunotherapy are poorly effective as they do not significantly increase the long-term survival of glioblastoma patients.
Azza hamad, G. Yusubalieva, V. Baklaushev, P. Chumakov, A. Lipatova   +4 more
semanticscholar   +1 more source

Topographical Mapping of 436 Newly Diagnosed IDH Wildtype Glioblastoma With vs. Without MGMT Promoter Methylation

Frontiers in Oncology, 2020
Introduction: O6-methylguanine-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase (IDH) mutation status are important prognostic factors for patients with glioblastoma.
Fatih Incekara, Fatih Incekara, Sebastian R. van der Voort, Hendrikus J. Dubbink, Peggy N. Atmodimedjo, Rishi Nandoe Tewarie, Geert Lycklama, Arnaud J. P. E. Vincent, Johan M. Kros, Stefan Klein, Martin van den Bent, Marion Smits   +11 more
doaj   +1 more source

Role of Molecular Targeted Therapeutic Drugs in Treatment of Glioblastoma: A Review Article

Global Medical Genetics, 2023
Glioblastoma is remarkably periodic primary brain tumor, characterizing an eminently heterogeneous pattern of neoplasms that are utmost destructive and threatening cancers.
Himanshu Singh
doaj   +1 more source

Glioblastoma familiar [PDF]

Arquivos de Neuro-Psiquiatria, 1995
The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities.
Arruda, Walter O., Clemente, Rogério S., Ramina, Ricardo, Pedrozo, Ari A., Pilotto, Rui F., Pinto Jr., Walter, Bleggi-torres, Luiz F.   +6 more
openaire   +4 more sources

β3GNT9 as a prognostic biomarker in glioblastoma and its association with glioblastoma immune infiltration, migration and invasion

Frontiers in Oncology, 2023
BackgroundStudies have shown that the immune infiltration of tumor microenvironment is related to the prognosis of glioblastoma, which is characterized by high heterogeneity, high recurrence rate and low survival rate.
YingHao Luo, Kan Wang, Lu Zhan, Fanyue Zeng, Jie Zheng, Sijing Chen, Xingbang Duan, Donghui Ju   +7 more
doaj   +1 more source

Prognostic validation of a new classification system for extent of resection in glioblastoma: A report of the RANO resect group

Neuro-Oncology, 2022
Background Terminology to describe extent of resection in glioblastoma is inconsistent across clinical trials. A surgical classification system was previously proposed based upon residual contrast-enhancing (CE) tumor.
P. Karschnia, Jacob S. Young, A. Dono, L. Häni, T. Sciortino, F. Bruno, S. Juenger, N. Teske, R. Morshed, Alexander F. Haddad, Yalan Zhang, Sophia Stoecklein, M. Weller, M. Vogelbaum, J. Beck, N. Tandon, S. Hervey-Jumper, A. Molinaro, R. Rudà, L. Bello, O. Schnell, Y. Esquenazi, M. Ruge, S. Grau, M. Berger, Susan M. Chang, M. J. van den Bent, J. Tonn   +27 more
semanticscholar   +1 more source