Results 11 to 20 of about 222,357 (321)
Background Radiotherapy, chemotherapy, and surgery have made crucial strides in glioblastoma treatment, yet they often fail; thus, new treatment and new detection methods are needed.
Fengyu Zhang+4 more
doaj +1 more source
Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents overexpression of mesenchymal markers Snail, Slug, and N-Cadherin and of the autophagic marker ...
Alejandro Urdiciain+9 more
doaj +1 more source
The Rio Hortega University Hospital Glioblastoma dataset: a comprehensive collection of preoperative, early postoperative and recurrence MRI scans (RHUH-GBM) [PDF]
Glioblastoma, a highly aggressive primary brain tumor, is associated with poor patient outcomes. Although magnetic resonance imaging (MRI) plays a critical role in diagnosing, characterizing, and forecasting glioblastoma progression, public MRI repositories present significant drawbacks, including insufficient postoperative and follow-up studies as ...
arxiv +1 more source
Immunovirotherapy for glioblastoma [PDF]
Virotherapy, the use of oncolytic viruses for cancer therapy, is an old concept currently making substantial clinical progress. Oncolytic viruses, whose tumor selectivity is genetically engineered or naturally occurring, replicate in and kill cancer cells but not normal tissue, and thus have the potential to amplify themselves in situ and spread ...
Hiroaki Wakimoto+2 more
openaire +3 more sources
The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities.
Arruda, Walter O.+6 more
openaire +4 more sources
The adaptive transition of glioblastoma stem cells and its implications on treatments
Glioblastoma is the most malignant tumor occurring in the human central nervous system with overall median survival time
Zeyu Wang+4 more
doaj +1 more source
Introduction: O6-methylguanine-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase (IDH) mutation status are important prognostic factors for patients with glioblastoma.
Fatih Incekara+11 more
doaj +1 more source
MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma
Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of various tumors, including the glioblastoma.
Peng Xu+7 more
doaj +1 more source
Role of Molecular Targeted Therapeutic Drugs in Treatment of Glioblastoma: A Review Article
Glioblastoma is remarkably periodic primary brain tumor, characterizing an eminently heterogeneous pattern of neoplasms that are utmost destructive and threatening cancers.
Himanshu Singh
doaj +1 more source
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang+10 more
doaj +1 more source