Results 11 to 20 of about 252,843 (247)

β3GNT9 as a prognostic biomarker in glioblastoma and its association with glioblastoma immune infiltration, migration and invasion

Frontiers in Oncology, 2023
BackgroundStudies have shown that the immune infiltration of tumor microenvironment is related to the prognosis of glioblastoma, which is characterized by high heterogeneity, high recurrence rate and low survival rate.
YingHao Luo, Kan Wang, Lu Zhan, Fanyue Zeng, Jie Zheng, Sijing Chen, Xingbang Duan, Donghui Ju   +7 more
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Topographical Mapping of 436 Newly Diagnosed IDH Wildtype Glioblastoma With vs. Without MGMT Promoter Methylation

Frontiers in Oncology, 2020
Introduction: O6-methylguanine-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase (IDH) mutation status are important prognostic factors for patients with glioblastoma.
Fatih Incekara, Fatih Incekara, Sebastian R. van der Voort, Hendrikus J. Dubbink, Peggy N. Atmodimedjo, Rishi Nandoe Tewarie, Geert Lycklama, Arnaud J. P. E. Vincent, Johan M. Kros, Stefan Klein, Martin van den Bent, Marion Smits   +11 more
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Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells

BMC Cancer, 2020
Background Glioblastoma is devastating cancer with a high frequency of occurrence and poor survival rate and it is urgent to discover novel glioblastoma-specific antigens for the therapy. Cancer-germline genes are known to be related to the formation and
Fengyu Zhang, Ruilai Liu, Haishi Zhang, Cheng Liu, Chunfang Liu, Yuan Lu   +5 more
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Optimization of Tumor Targeting Gold Nanoparticles for Glioblastoma Applications

Nanomaterials, 2022
Glioblastoma brain tumors represent an aggressive form of gliomas that is hallmarked by being extremely invasive and aggressive due to intra and inter-tumoral heterogeneity.
Nicholas C. Allen, Rajat Chauhan, Paula J. Bates, Martin G. O’Toole   +3 more
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Regulatory pattern of abnormal promoter CpG island methylation in the glioblastoma multiforme classification

Frontiers in Genetics, 2022
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang, Rendong Wang, Lei Zhao, Shijia Wang, Shijia Wang, Xiaoxiao Zhao, Xiaoxiao Zhao, Chuanyu Liang, Pei Wang, Dongguo Li, Dongguo Li   +10 more
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MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma

Analytical Cellular Pathology, 2022
Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of various tumors, including the glioblastoma.
Peng Xu, Fei-Hang Ge, Wen-Xin Li, Zhen Xu, Xue-Li Wang, Jing-Lan Shen, Ai-Bo Xu, Rong-Rong Hao   +7 more
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Research Progress of Diagnosis and Treatment of Glioblastoma

Zhongliu Fangzhi Yanjiu, 2022
Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
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TRIM7 modulates NCOA4-mediated ferritinophagy and ferroptosis in glioblastoma cells

Redox Biology, 2022
Objective: Glioblastoma is one of the most common intracranial malignant tumors with an unfavorable prognosis, and iron metabolism as well as ferroptosis are implicated in the pathogenesis of glioblastoma.
Kaiqiang Li, Bingyu Chen, Aibo Xu, Jinglan Shen, Kaixuan Li, Ke Hao, Rongrong Hao, Wei Yang, Wanli Jiang, Yongfa Zheng, Feihang Ge, Zhen Wang   +11 more
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Glioblastoma: Changing concepts in the WHO CNS5 classification

Indian Journal of Pathology and Microbiology, 2022
Glioblastoma is the most common malignant central nervous system (CNS) tumor in adults. Acute common clinical symptoms include headache, seizure, behavior changes, focal neurological deficits, and signs of increased intracranial pressure. The classic MRI
Jie Chen, Pengcheng Han, Sonika Dahiya
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RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis

Biomedicines, 2021
Up to now, the chemotherapy approaches for glioblastoma were limited. 1-[2-Thiazolylazo]-2-naphthol (named as NSC139021) was shown to significantly inhibit the proliferation of prostate cancer cells by targeting the atypical protein kinase RIOK2.
Min Yu, Xiaoyan Hu, Jingyu Yan, Ying Wang, Fei Lu, Junlei Chang   +5 more
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