Results 11 to 20 of about 222,357 (321)

Nanos3, a cancer-germline gene, promotes cell proliferation, migration, chemoresistance, and invasion of human glioblastoma

open access: yesCancer Cell International, 2020
Background Radiotherapy, chemotherapy, and surgery have made crucial strides in glioblastoma treatment, yet they often fail; thus, new treatment and new detection methods are needed.
Fengyu Zhang   +4 more
doaj   +1 more source

Silencing of Histone Deacetylase 6 Decreases Cellular Malignancy and Contributes to Primary Cilium Restoration, Epithelial-to-Mesenchymal Transition Reversion, and Autophagy Inhibition in Glioblastoma Cell Lines

open access: yesBiology, 2021
Glioblastoma multiforme, the most common type of malignant brain tumor as well as the most aggressive one, lacks an effective therapy. Glioblastoma presents overexpression of mesenchymal markers Snail, Slug, and N-Cadherin and of the autophagic marker ...
Alejandro Urdiciain   +9 more
doaj   +1 more source

The Rio Hortega University Hospital Glioblastoma dataset: a comprehensive collection of preoperative, early postoperative and recurrence MRI scans (RHUH-GBM) [PDF]

open access: yes, 2023
Glioblastoma, a highly aggressive primary brain tumor, is associated with poor patient outcomes. Although magnetic resonance imaging (MRI) plays a critical role in diagnosing, characterizing, and forecasting glioblastoma progression, public MRI repositories present significant drawbacks, including insufficient postoperative and follow-up studies as ...
arxiv   +1 more source

Immunovirotherapy for glioblastoma [PDF]

open access: yesCell Cycle, 2013
Virotherapy, the use of oncolytic viruses for cancer therapy, is an old concept currently making substantial clinical progress. Oncolytic viruses, whose tumor selectivity is genetically engineered or naturally occurring, replicate in and kill cancer cells but not normal tissue, and thus have the potential to amplify themselves in situ and spread ...
Hiroaki Wakimoto   +2 more
openaire   +3 more sources

Glioblastoma familiar [PDF]

open access: yesArquivos de Neuro-Psiquiatria, 1995
The authors describe a family with three members affected by glioblastoma. The proband patient, a 7 year-old girl, developed a rare complication, a pulmonary metastasis. Chromosomal analysis of her peripheral blood lymphocytes showed a normal karyotype (46, XX), without structural abnormalities.
Arruda, Walter O.   +6 more
openaire   +4 more sources

The adaptive transition of glioblastoma stem cells and its implications on treatments

open access: yesSignal Transduction and Targeted Therapy, 2021
Glioblastoma is the most malignant tumor occurring in the human central nervous system with overall median survival time
Zeyu Wang   +4 more
doaj   +1 more source

Topographical Mapping of 436 Newly Diagnosed IDH Wildtype Glioblastoma With vs. Without MGMT Promoter Methylation

open access: yesFrontiers in Oncology, 2020
Introduction: O6-methylguanine-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase (IDH) mutation status are important prognostic factors for patients with glioblastoma.
Fatih Incekara   +11 more
doaj   +1 more source

MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma

open access: yesAnalytical Cellular Pathology, 2022
Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of various tumors, including the glioblastoma.
Peng Xu   +7 more
doaj   +1 more source

Role of Molecular Targeted Therapeutic Drugs in Treatment of Glioblastoma: A Review Article

open access: yesGlobal Medical Genetics, 2023
Glioblastoma is remarkably periodic primary brain tumor, characterizing an eminently heterogeneous pattern of neoplasms that are utmost destructive and threatening cancers.
Himanshu Singh
doaj   +1 more source

Regulatory pattern of abnormal promoter CpG island methylation in the glioblastoma multiforme classification

open access: yesFrontiers in Genetics, 2022
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang   +10 more
doaj   +1 more source

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