Results 41 to 50 of about 258,291 (316)

What is the role of CRP in glioblastoma?

Cancer Treatment and Research Communications, 2021
Background: Glioblastoma is the most common primary malignant brain tumor in adults. Previous studies have suggested that CRP (C-reactive protein) could serve as a biomarker candidate as well as a prognostic factor in glioblastoma patients, and we here ...
Karolina Förnvik, Aida Maddahi, Emma Liljedahl, Kurt Osther, Leif G. Salford, Henrietta Nittby Redebrandt   +5 more
doaj   +1 more source

Treatment of Glioblastoma [PDF]

Journal of Oncology Practice, 2017
Glioblastoma is the most common and most aggressive form of primary brain tumor in adults and contributes to high social and medical burden as a result of its incurable nature and significant neurologic morbidity. Despite ongoing research, there has not been improvement in survival in glioblastoma.
Joo Yeon, Nam, John F, de Groot
openaire   +2 more sources

Development of armed oncolytic agents based on the herpes simplex virus type 1 for the treatment of glioblastoma [PDF]

, 2023
openGlioblastoma (GBM) is one of the most common and aggressive malignant brain tumors in adults. Patients affected by glioblastoma show poor prognosis and low survival rate after the diagnosis.
ZAGO, ALESSIA
core  

Vagus nerve stimulation: Novel concept for the treatment of glioblastoma and solid cancers by cytokine (interleukin-6) reduction, attenuating the SASP, enhancing tumor immunity

Brain, Behavior, & Immunity - Health
Immuno-oncology, specifically immune checkpoint inhibitors (ICIs), has revolutionized cancer care with dramatic, long-term responses and increased survival, including patients with metastatic cancer to the brain.
Steven Brem
doaj   +1 more source

Adverse prognosis and distinct progression patterns after concurrent chemoradiotherapy for glioblastoma with synchronous subventricular zone and corpus callosum invasion [PDF]

, 2017
Background and purpose: The subventricular zone (SVZ) and the corpus callosum (CC) invasion status are separately associated with adverse prognosis for glioblastoma.
Liang, Tony Hsiang-Kuang;Kuo, Sung-Hsin;Wang, Chun-Wei;Chen, Wan-Yu;Hsu, Che-Yu;Lai, Shih-Fan;Tseng, Ham-Min;You, San-Lin;Chen, Chung-Ming;Tseng, Wen-Yih Isaac, 曾漢民;曾文毅;陳中明;陳婉瑜;郭頌鑫;梁祥光;王駿瑋   +1 more
core   +1 more source

The anti‐hypertensive drug prazosin inhibits glioblastoma growth via the PKCδ‐dependent inhibition of the AKT pathway

EMBO Molecular Medicine, 2016
A variety of drugs targeting monoamine receptors are routinely used in human pharmacology. We assessed the effect of these drugs on the viability of tumor‐initiating cells isolated from patients with glioblastoma.
Suzana Assad Kahn, Silvia Lima Costa, Sharareh Gholamin, Ryan T Nitta, Luiz Gustavo Dubois, Marie Fève, Maria Zeniou, Paulo Lucas Cerqueira Coelho, Elias El‐Habr, Josette Cadusseau, Pascale Varlet, Siddhartha S Mitra, Bertrand Devaux, Marie‐Claude Kilhoffer, Samuel H Cheshier, Vivaldo Moura‐Neto, Jacques Haiech, Marie‐Pierre Junier, Hervé Chneiweiss   +18 more
doaj   +1 more source

A systematic review on poly(I:C) and poly-ICLC in glioblastoma: adjuvants coordinating the unlocking of immunotherapy

Journal of Experimental & Clinical Cancer Research, 2021
Immunotherapy is currently under intensive investigation as a potential breakthrough treatment option for glioblastoma. Given the anatomical and immunological complexities surrounding glioblastoma, lymphocytes that infiltrate the brain to develop durable
Jorrit De Waele, Tias Verhezen, Sanne van der Heijden, Zwi N. Berneman, Marc Peeters, Filip Lardon, An Wouters, Evelien L. J. M. Smits   +7 more
doaj   +1 more source

3-Bromofascaplysin is a prospective chemical compound for developing new chemotherapy agents in glioblastoma treatment [PDF]

, 2020
Glioblastoma (GB) is one of the most aggressive human brain tumors. The prognosis is unfavorable, its treatment is relatively ineffective, and the median survival is about 15months. Medication development with new chemical compounds is one of the ways to
Alexey Kantemirov, Piatkova, Mariia,, Khotimchenko, Rodion,, Sharma, Aruna,, Maxim Zhidkov, Kantemirov, Alexey,, Bryukhovetskiy, Igor,, Andrey Bryukhovetskiy, Lyakhova, Irina,, Zhidkov, Maxim,, Rodion Khotimchenko, Mariia Piatkova, Hari Shanker Sharma, Aruna Sharma, Igor Bryukhovetskiy, Khotimchenko, Yuri,, Bryukhovetskiy, Andrey,, Yuri Khotimchenko, Irina Lyakhova, Sharma, Hari Shanker,   +19 more
core   +1 more source

Abnormal Schwannoma-like Growth of multiple, multifocal BRAF V600E-positive Glioblastoma in the Interior Acoustic Canal with Leptomeningeal Infiltration: a case report

Journal of Medical Case Reports, 2022
Background Glioblastoma belongs to the most common and most aggressive tumor entity of the central nervous system with a poor prognosis of only few months.
Roopa Jayarama-Naidu, Evelyn Gallus
doaj   +1 more source

Characterising Distinct Migratory Profiles of Infiltrating T-Cell Subsets in Human Glioblastoma

Frontiers in Immunology, 2022
Glioblastoma is the most common and aggressive form of primary brain cancer, with no improvements in the 5-year survival rate of 4.6% over the past three decades.
Paris M. Kollis, Paris M. Kollis, Lisa M. Ebert, Lisa M. Ebert, Lisa M. Ebert, John Toubia, Cameron R. Bastow, Rebecca J. Ormsby, Santosh I. Poonnoose, Santosh I. Poonnoose, Sakthi Lenin, Melinda N. Tea, Stuart M. Pitson, Stuart M. Pitson, Guillermo A. Gomez, Michael P. Brown, Michael P. Brown, Michael P. Brown, Tessa Gargett, Tessa Gargett, Tessa Gargett   +20 more
doaj   +1 more source