Results 31 to 40 of about 358,441 (297)
Advanced Magnetic Resonance Imaging in Glioblastoma: A Review [PDF]
, 2018 INTRODUCTION In 2017, it is estimated that 26,070 patients will be diagnosed with a malignant primary brain tumor in the United States, with more than half having the diagnosis of glioblas- toma (GBM).1 Magnetic resonance imaging (MRI) is a widely ...
Alexander, G. S. +6 more
core +2 more sources
Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma
Microorganisms, 2020 Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto +3 more
doaj +1 more source
Chinese Medical Journal, 2021 . Background. Previous studies have demonstrated that various circular RNAs are involved in the malignant proliferation of cancers, such as liver cancer, lung cancer, breast cancer, and others. The potential role of circular RNAs in glioblastoma, however,
Jin-Xu Zhou +8 more
doaj +1 more source
Bone morphogenetic protein 7 sensitizes O6-methylguanine methyltransferase expressing-glioblastoma stem cells to clinically relevant dose of temozolomide. [PDF]
, 2015 BackgroundTemozolomide (TMZ) is an oral DNA-alkylating agent used for treating patients with glioblastoma. However, therapeutic benefits of TMZ can be compromised by the expression of O6-methylguanine methyltransferase (MGMT) in tumor tissue.
Bui, Yvonne +14 more
core +2 more sources
What is the role of CRP in glioblastoma?
Cancer Treatment and Research Communications, 2021 Background: Glioblastoma is the most common primary malignant brain tumor in adults. Previous studies have suggested that CRP (C-reactive protein) could serve as a biomarker candidate as well as a prognostic factor in glioblastoma patients, and we here ...
Karolina Förnvik +5 more
doaj +1 more source
MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma
Journal of Experimental & Clinical Cancer Research, 2019 Background Glioblastoma is a malignant brain tumor characterized by rapid growth, diffuse invasion and therapeutic resistance. We recently used microRNA expression profiles to subclassify glioblastoma into five genetically and clinically distinct ...
Yun Zhao +10 more
doaj +1 more source
The role of the Bmi1-GSK3β pathway in glioblastoma [PDF]
, 2010 Malignant gliomas remain one of the deadliest of all cancers despite maximal therapy. They present unique challenges to therapy with a median survival of 12 months.
Korur, Serdar
core +1 more source
Frontiers in Genetics, 2022 Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang +10 more
doaj +1 more source
Therapeutic approach in glioblastoma multiforme with primitive neuroectodermal tumor components: case report and review of the literature [PDF]
, 2018 Glioblastoma multiforme (GBM) is the most common and aggressive malignant glioma that is treated with first-line therapy, using surgical resection followed by local radiotherapy and concomitant/adjuvant temozolomide (TMZ) treatment.
Berrios J. R. G. +12 more
core +1 more source
Identification of an Efficient Gene Expression Panel for Glioblastoma Classification. [PDF]
, 2016 We present here a novel genetic algorithm-based random forest (GARF) modeling technique that enables a reduction in the complexity of large gene disease signatures to highly accurate, greatly simplified gene panels.
Coppola, Giovanni +7 more
core +2 more sources