Results 31 to 40 of about 81,769 (261)

Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

Microorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto, Mattia Russel Pantalone, Afsar Rahbar, Cecilia Söderberg-Nauclér   +3 more
doaj   +1 more source

Regulatory pattern of abnormal promoter CpG island methylation in the glioblastoma multiforme classification

Frontiers in Genetics, 2022
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang, Rendong Wang, Lei Zhao, Shijia Wang, Shijia Wang, Xiaoxiao Zhao, Xiaoxiao Zhao, Chuanyu Liang, Pei Wang, Dongguo Li, Dongguo Li   +10 more
doaj   +1 more source

Research Progress of Diagnosis and Treatment of Glioblastoma

Zhongliu Fangzhi Yanjiu, 2022
Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
doaj   +1 more source

Neddylation in glioblastomas [PDF]

Neuro-Oncology, 2015
Protein degradation is a highly regulated process that is required for maintaining cellular homeostasis, and its deregulation is associated with development of a number of diseases including cancer. Neddylation is a posttranslational modification that involves conjugation of the ubiquitin-like protein NEDD8 (neural precursor cell expressed ...
Sheila, Mansouri, Gelareh, Zadeh
openaire   +2 more sources

Electrotherapies for Glioblastoma [PDF]

Advanced Science, 2021
AbstractNon‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) which induce reversible or irreversible electroporation (IRE) and tumour‐treating fields (TTFs) are reviewed highlighting the foundations, advances, and considerations of each
Jenkins, E. P. W., Finch, A., Gerigk, M., Triantis, I., Watts, C., Malliaras, G. G.   +5 more
openaire   +6 more sources

Alkaloids of fascaplysin are promising chemotherapeutic agents for the treatment of glioblastoma: Review

, 2020
Glioblastoma is one of the most aggressive human brain tumors. Even following all the modern protocols of complex treatment, the median patient survival typically does not exceed 15 months.
Valeriia Gulaia, Piatkova, Mariia,, Khotimchenko, Rodion,, Sharma, Aruna,, Mikhail Shmelev, Gulaia, Valeriia,, Bryukhovetskiy, Igor,, Andrey Bryukhovetskiy, Lyakhova, Irina,, Rodion Khotimchenko, Mariia Piatkova, Hari Shanker Sharma, Romanishin, Aleksandr,, Aruna Sharma, Igor Bryukhovetskiy, Bryukhovetskiy, Andrey,, Irina Lyakhova, Aleksandr Romanishin, Shmelev, Mikhail,, Sharma, Hari Shanker,   +19 more
core   +1 more source

MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma

Journal of Experimental & Clinical Cancer Research, 2019
Background Glioblastoma is a malignant brain tumor characterized by rapid growth, diffuse invasion and therapeutic resistance. We recently used microRNA expression profiles to subclassify glioblastoma into five genetically and clinically distinct ...
Yun Zhao, Wei Huang, Tae-Min Kim, Yuchae Jung, Lata G. Menon, Hongyan Xing, Hongwei Li, Rona S. Carroll, Peter J. Park, Hong Wei Yang, Mark D. Johnson   +10 more
doaj   +1 more source

What is the role of CRP in glioblastoma?

Cancer Treatment and Research Communications, 2021
Background: Glioblastoma is the most common primary malignant brain tumor in adults. Previous studies have suggested that CRP (C-reactive protein) could serve as a biomarker candidate as well as a prognostic factor in glioblastoma patients, and we here ...
Karolina Förnvik, Aida Maddahi, Emma Liljedahl, Kurt Osther, Leif G. Salford, Henrietta Nittby Redebrandt   +5 more
doaj   +1 more source

Development of armed oncolytic agents based on the herpes simplex virus type 1 for the treatment of glioblastoma [PDF]

, 2023
openGlioblastoma (GBM) is one of the most common and aggressive malignant brain tumors in adults. Patients affected by glioblastoma show poor prognosis and low survival rate after the diagnosis.
ZAGO, ALESSIA
core  

Vagus nerve stimulation: Novel concept for the treatment of glioblastoma and solid cancers by cytokine (interleukin-6) reduction, attenuating the SASP, enhancing tumor immunity

Brain, Behavior, & Immunity - Health
Immuno-oncology, specifically immune checkpoint inhibitors (ICIs), has revolutionized cancer care with dramatic, long-term responses and increased survival, including patients with metastatic cancer to the brain.
Steven Brem
doaj   +1 more source