Results 11 to 20 of about 358,441 (297)

β3GNT9 as a prognostic biomarker in glioblastoma and its association with glioblastoma immune infiltration, migration and invasion

Frontiers in Oncology, 2023
BackgroundStudies have shown that the immune infiltration of tumor microenvironment is related to the prognosis of glioblastoma, which is characterized by high heterogeneity, high recurrence rate and low survival rate.
YingHao Luo, Kan Wang, Lu Zhan, Fanyue Zeng, Jie Zheng, Sijing Chen, Xingbang Duan, Donghui Ju   +7 more
doaj   +1 more source

The Potential Roles of Long Noncoding RNAs (lncRNA) in Glioblastoma Development [PDF]

, 2016
Long noncoding RNA (lncRNA) may contribute to the initiation and progression of tumor. In this study, we first systematically compared lncRNA and mRNA expression between glioblastoma and paired normal brain tissues using microarray data.
Eischen, Christine M., Fan, Wenhong, Liu, Shuang, Mitra, Ramkrishna, Yin, Feng, Zhao, Ming-Ming, Zhao, Zhongming   +6 more
core   +2 more sources

Nanos3, a cancer-germline gene, promotes cell proliferation, migration, chemoresistance, and invasion of human glioblastoma

Cancer Cell International, 2020
Background Radiotherapy, chemotherapy, and surgery have made crucial strides in glioblastoma treatment, yet they often fail; thus, new treatment and new detection methods are needed.
Fengyu Zhang, Ruilai Liu, Cheng Liu, Haishi Zhang, Yuan Lu   +4 more
doaj   +1 more source

Fermented mistletoe extract as a multimodal antitumoral agent in gliomas [PDF]

, 2012
In Europe, commercially available extracts from the white-berry mistletoe (Viscum album L.) are widely used as a complementary cancer therapy. Mistletoe lectins have been identified as main active components and exhibit cytotoxic effects as well as ...
Harter, Patrick Nikolaus, Mittelbronn, Michel Guy André, Naumann, Ulrike, Podlech, Oliver, Pöschel, Simone   +4 more
core   +2 more sources

Topographical Mapping of 436 Newly Diagnosed IDH Wildtype Glioblastoma With vs. Without MGMT Promoter Methylation

Frontiers in Oncology, 2020
Introduction: O6-methylguanine-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase (IDH) mutation status are important prognostic factors for patients with glioblastoma.
Fatih Incekara, Fatih Incekara, Sebastian R. van der Voort, Hendrikus J. Dubbink, Peggy N. Atmodimedjo, Rishi Nandoe Tewarie, Geert Lycklama, Arnaud J. P. E. Vincent, Johan M. Kros, Stefan Klein, Martin van den Bent, Marion Smits   +11 more
doaj   +1 more source

Optimization of Tumor Targeting Gold Nanoparticles for Glioblastoma Applications

Nanomaterials, 2022
Glioblastoma brain tumors represent an aggressive form of gliomas that is hallmarked by being extremely invasive and aggressive due to intra and inter-tumoral heterogeneity.
Nicholas C. Allen, Rajat Chauhan, Paula J. Bates, Martin G. O’Toole   +3 more
doaj   +1 more source

Impact of Human Immunodeficiency Virus in the Pathogenesis and Outcome of Patients with Glioblastoma Multiforme. [PDF]

, 2016
BackgroundImprovement in antiviral therapies have been accompanied by an increased frequency of non-Acquired Immune Deficiency Syndrome (AIDS) defining malignancies, such as glioblastoma multiforme.
Bui, Timothy T, Choy, Winward, Lagman, Carlito, Lee, Seung J, Safaee, Michael, Yang, Isaac   +5 more
core   +1 more source

Valosin-containing protein regulates the proteasome-mediated degradation of DNA-PKcs in glioma cells. [PDF]

, 2013
DNA-dependent protein kinase (DNA-PK) has an important role in the repair of DNA damage and regulates the radiation sensitivity of glioblastoma cells. The VCP (valosine-containing protein), a chaperone protein that regulates ubiquitin-dependent protein ...
Cao, L, Fei, X, Jiang, N, Kong, X, Larner, J, Mi, J, Qiu, Y, Shen, Y, Sheng, K, Sun, P   +9 more
core   +1 more source

Extracellular Vesicle-Mediated Communication between the Glioblastoma and Its Microenvironment [PDF]

, 2019
The glioblastoma is the most malignant form of brain cancer. Glioblastoma cells use multiple ways of communication with the tumor microenvironment in order to tune it for their own benefit.
Pastor Loro, Ángel Manuel, Rodríguez Matarredona, Esperanza   +1 more
core   +1 more source

Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells

BMC Cancer, 2020
Background Glioblastoma is devastating cancer with a high frequency of occurrence and poor survival rate and it is urgent to discover novel glioblastoma-specific antigens for the therapy. Cancer-germline genes are known to be related to the formation and
Fengyu Zhang, Ruilai Liu, Haishi Zhang, Cheng Liu, Chunfang Liu, Yuan Lu   +5 more
doaj   +1 more source