Results 11 to 20 of about 81,769 (261)

Novel Treatment Strategies for Glioblastoma [PDF]

, 2021
This book is a compilation of articles that brings together current knowledge from an international team of contributors who are dedicated investigators exploring novel strategies for the treatment of glioblastoma.

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The role of TGFb/SMAD signaling in glioblastoma

Folia Neuropathologica
Glioblastoma is a multifaceted and therapeutically challenging disease. Despite decades of ground-breaking research work, therapeutic options for the cure of glioblastoma are limited.
Gulnara Kapanova, Aigul Tulebayeva, Aigul Bazarbayeva, Assiya Turgambayeva, Aida Akhenbekova, Akmaral Abdykulova, Almat Kodasbayev, Aima Adylova   +7 more
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Non-operable glioblastoma: Proposition of patient-specific forecasting by image-informed poromechanical model [PDF]

, 2023
Work funding with a grant fromLuxembourg National Research Fund (FNR) grant number INTER/ANR/21/16399490 and from Réseau Santé des Arts et Métiers.We propose a novel image-informed glioblastoma mathematical model within a reactive multiphase ...
ROHAN, Pierre-Yves, Davide Baroli, URCUN, Stéphane, Wafa Skalli, Giuseppe Sciumè, BORDAS, Stéphane Pierre Alain, Stéphane P.A. Bordas, SKALLI, Wafa, Stéphane Urcun, SCIUME, Giuseppe, LUBRANO, Vincent, BAROLI, Davide, Bordas, Stéphane, P A, Vincent Lubrano, Pierre-Yves Rohan   +14 more
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Nanos3, a cancer-germline gene, promotes cell proliferation, migration, chemoresistance, and invasion of human glioblastoma

Cancer Cell International, 2020
Background Radiotherapy, chemotherapy, and surgery have made crucial strides in glioblastoma treatment, yet they often fail; thus, new treatment and new detection methods are needed.
Fengyu Zhang, Ruilai Liu, Cheng Liu, Haishi Zhang, Yuan Lu   +4 more
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Role of Molecular Targeted Therapeutic Drugs in Treatment of Glioblastoma: A Review Article

Global Medical Genetics, 2023
Glioblastoma is remarkably periodic primary brain tumor, characterizing an eminently heterogeneous pattern of neoplasms that are utmost destructive and threatening cancers.
Himanshu Singh
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Topographical Mapping of 436 Newly Diagnosed IDH Wildtype Glioblastoma With vs. Without MGMT Promoter Methylation

Frontiers in Oncology, 2020
Introduction: O6-methylguanine-methyltransferase (MGMT) promoter methylation and isocitrate dehydrogenase (IDH) mutation status are important prognostic factors for patients with glioblastoma.
Fatih Incekara, Fatih Incekara, Sebastian R. van der Voort, Hendrikus J. Dubbink, Peggy N. Atmodimedjo, Rishi Nandoe Tewarie, Geert Lycklama, Arnaud J. P. E. Vincent, Johan M. Kros, Stefan Klein, Martin van den Bent, Marion Smits   +11 more
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Immunovirotherapy for glioblastoma [PDF]

Cell Cycle, 2013
Virotherapy, the use of oncolytic viruses for cancer therapy, is an old concept currently making substantial clinical progress. Oncolytic viruses, whose tumor selectivity is genetically engineered or naturally occurring, replicate in and kill cancer cells but not normal tissue, and thus have the potential to amplify themselves in situ and spread ...
Ning, Jianfang, Wakimoto, Hiroaki, Rabkin, Samuel D   +2 more
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Novel therapeutic venues for glioblastoma: novel rising preclinical treatment opportunities [PDF]

, 2011
High grade gliomas, including anaplastic glioma WHO grade III and glioblastoma WHO IV (GBM), carry a dismal prognosis. Taking all nowadays-available therapeutics options, including radiation, chemotherapy and surgery, for GBM into consideration the ...
Siegelin, Yasemin, Siegelin Yasemi, Siegelin, Markus David, Siegelin Markus David, Siegelin Yasemin, Siegelin Markus   +5 more
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Efficient chemotherapy of rat glioblastoma using Doxorubicin-loaded PLGA nanoparticles with different stabilizers [PDF]

, 2011
Background: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain.
Markus Glatzel, Kreuter, Jörg (Prof. Dr.), Christian Bernreuther, Olga Maksimenko, Maksimenko, Olga, Khalansky, Alexander S., Jörg Kreuter, Wohlfart, Stefanie, Gelperina, Svetlana, Svetlana Gelperina, Bernreuther, Christian, Stefanie Wohlfart, Alexander S Khalansky, Glatzel, Markus, Alexander S. Khalansky   +14 more
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Remission of invasive, cancer stem-like glioblastoma xenografts using lentiviral vector-mediated suicide gene therapy [PDF]

, 2009
Background: Glioblastoma is the most frequent and most malignant primary brain tumor with a poor prognosis. The translation of therapeutic strategies for glioblastoma from the experimental phase into the clinic has been limited by insufficient animal ...
Oleg Tsinkalovsky, Euskirchen Philipp, Tsanan Giroglou, Huszthy, Peter C., Giroglou Tsanan, Skaftnesmo, Kai Ove, Miletic, Hrvoje, Miletic Hrvoje, Peter C Huszthy, Kai Ove Skaftnesmo, Tsinkalovsky Oleg, von Laer Dorothee, Euskirchen, Philipp, Dorothee von Laer, Hrvoje Miletic, Laer, Dorothee von, Rolf Bjerkvig, Giroglou, Tsanan, Tsinkalovsky, Oleg, Huszthy Peter C., Skaftnesmo Kai Ove, Bjerkvig Rolf, Philipp Euskirchen, Bjerkvig, Rolf   +23 more
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