Results 21 to 30 of about 202,953 (268)
Research Progress of Diagnosis and Treatment of Glioblastoma
Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
doaj +1 more source
Immunovirotherapy for glioblastoma [PDF]
Virotherapy, the use of oncolytic viruses for cancer therapy, is an old concept currently making substantial clinical progress. Oncolytic viruses, whose tumor selectivity is genetically engineered or naturally occurring, replicate in and kill cancer cells but not normal tissue, and thus have the potential to amplify themselves in situ and spread ...
Ning, Jianfang +2 more
openaire +2 more sources
Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto +3 more
doaj +1 more source
What is the role of CRP in glioblastoma?
Background: Glioblastoma is the most common primary malignant brain tumor in adults. Previous studies have suggested that CRP (C-reactive protein) could serve as a biomarker candidate as well as a prognostic factor in glioblastoma patients, and we here ...
Karolina Förnvik +5 more
doaj +1 more source
Neddylation in glioblastomas [PDF]
Protein degradation is a highly regulated process that is required for maintaining cellular homeostasis, and its deregulation is associated with development of a number of diseases including cancer. Neddylation is a posttranslational modification that involves conjugation of the ubiquitin-like protein NEDD8 (neural precursor cell expressed ...
Sheila, Mansouri, Gelareh, Zadeh
openaire +2 more sources
Electrotherapies for Glioblastoma [PDF]
AbstractNon‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) which induce reversible or irreversible electroporation (IRE) and tumour‐treating fields (TTFs) are reviewed highlighting the foundations, advances, and considerations of each
Jenkins, E. P. W. +5 more
openaire +6 more sources
MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma
Background Glioblastoma is a malignant brain tumor characterized by rapid growth, diffuse invasion and therapeutic resistance. We recently used microRNA expression profiles to subclassify glioblastoma into five genetically and clinically distinct ...
Yun Zhao +10 more
doaj +1 more source
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang +10 more
doaj +1 more source
. Background. Previous studies have demonstrated that various circular RNAs are involved in the malignant proliferation of cancers, such as liver cancer, lung cancer, breast cancer, and others. The potential role of circular RNAs in glioblastoma, however,
Jin-Xu Zhou +8 more
doaj +1 more source
Background Glioblastoma belongs to the most common and most aggressive tumor entity of the central nervous system with a poor prognosis of only few months.
Roopa Jayarama-Naidu, Evelyn Gallus
doaj +1 more source

