Results 21 to 30 of about 212,897 (265)

Giant cell glioblastoma in the pediatric age group: Report of two cases

open access: yesJournal of Pediatric Neurosciences, 2013
Giant cell glioblastoma multiforme is a rare subgroup of glioblastoma multiforme. It constitutes about 5% of all glioblastoma cases. Pediatric giant cell glioblastoma is extremely rare. We report two such cases of giant cell glioblastoma in pediatric age
Sachin Anil Borkar   +4 more
doaj   +1 more source

Glioblastoma: Changing concepts in the WHO CNS5 classification

open access: yesIndian Journal of Pathology and Microbiology, 2022
Glioblastoma is the most common malignant central nervous system (CNS) tumor in adults. Acute common clinical symptoms include headache, seizure, behavior changes, focal neurological deficits, and signs of increased intracranial pressure. The classic MRI
Jie Chen, Pengcheng Han, Sonika Dahiya
doaj   +1 more source

RIOK2 Inhibitor NSC139021 Exerts Anti-Tumor Effects on Glioblastoma via Inducing Skp2-Mediated Cell Cycle Arrest and Apoptosis

open access: yesBiomedicines, 2021
Up to now, the chemotherapy approaches for glioblastoma were limited. 1-[2-Thiazolylazo]-2-naphthol (named as NSC139021) was shown to significantly inhibit the proliferation of prostate cancer cells by targeting the atypical protein kinase RIOK2.
Min Yu   +5 more
doaj   +1 more source

Up-regulation of circular RNA hsa_circ_01844 induces apoptosis and suppresses proliferation and migration of glioblastoma cells

open access: yesChinese Medical Journal, 2021
. Background. Previous studies have demonstrated that various circular RNAs are involved in the malignant proliferation of cancers, such as liver cancer, lung cancer, breast cancer, and others. The potential role of circular RNAs in glioblastoma, however,
Jin-Xu Zhou   +8 more
doaj   +1 more source

Regulatory pattern of abnormal promoter CpG island methylation in the glioblastoma multiforme classification

open access: yesFrontiers in Genetics, 2022
Glioblastoma (GBM) is characterized by extensive genetic and phenotypic heterogeneity. However, it remains unexplored primarily how CpG island methylation abnormalities in promoter mediate glioblastoma typing.
Rendong Wang   +10 more
doaj   +1 more source

Neddylation in glioblastomas [PDF]

open access: yesNeuro-Oncology, 2015
Protein degradation is a highly regulated process that is required for maintaining cellular homeostasis, and its deregulation is associated with development of a number of diseases including cancer. Neddylation is a posttranslational modification that involves conjugation of the ubiquitin-like protein NEDD8 (neural precursor cell expressed ...
Sheila, Mansouri, Gelareh, Zadeh
openaire   +2 more sources

Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

open access: yesMicroorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto   +3 more
doaj   +1 more source

Research Progress of Diagnosis and Treatment of Glioblastoma

open access: yesZhongliu Fangzhi Yanjiu, 2022
Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
doaj   +1 more source

Electrotherapies for Glioblastoma [PDF]

open access: yesAdvanced Science, 2021
AbstractNon‐thermal, intermediate frequency (100–500 kHz) electrotherapies present a unique therapeutic strategy to treat malignant neoplasms. Here, pulsed electric fields (PEFs) which induce reversible or irreversible electroporation (IRE) and tumour‐treating fields (TTFs) are reviewed highlighting the foundations, advances, and considerations of each
Jenkins, E. P. W.   +5 more
openaire   +6 more sources

MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Glioblastoma is a malignant brain tumor characterized by rapid growth, diffuse invasion and therapeutic resistance. We recently used microRNA expression profiles to subclassify glioblastoma into five genetically and clinically distinct ...
Yun Zhao   +10 more
doaj   +1 more source

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