Optimization of Tumor Targeting Gold Nanoparticles for Glioblastoma Applications
Nanomaterials, 2022 Glioblastoma brain tumors represent an aggressive form of gliomas that is hallmarked by being extremely invasive and aggressive due to intra and inter-tumoral heterogeneity.
Nicholas C. Allen +3 more
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Efficient chemotherapy of rat glioblastoma using Doxorubicin-loaded PLGA nanoparticles with different stabilizers [PDF]
, 2011 Background: Chemotherapy of glioblastoma is largely ineffective as the blood-brain barrier (BBB) prevents entry of most anticancer agents into the brain.
Markus Glatzel +14 more
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Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells
BMC Cancer, 2020 Background Glioblastoma is devastating cancer with a high frequency of occurrence and poor survival rate and it is urgent to discover novel glioblastoma-specific antigens for the therapy. Cancer-germline genes are known to be related to the formation and
Fengyu Zhang +5 more
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Adaptive Changes of Glioblastoma Cells Following Exposure to Hypoxic (1% Oxygen) Tumour Microenvironment [PDF]
, 2019 Glioblastoma multiforme is the most aggressive and malignant primary brain tumour, with a median survival rate of between 15 to 17 months. Heterogeneous regions occur in glioblastoma as a result of oxygen gradients which ranges from 0.1% to 10% in vivo ...
Musah-Eroje, Ahmed +3 more
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Combinatorial strategy using protein kinase inhibitors and a cytotoxic compound for highly resistant glioblastoma cells : "in vitro studies" [PDF]
, 2007 Glioblastoma multiforme (GBM) is the most frequent and the most aggesssive malignant neoplasm of the human central nervous system (CNS), with a median survival of less than one year. These neoplasms are radio- and chemo-resistant, and are highly invasive,
Failly, Mike
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TRIM7 modulates NCOA4-mediated ferritinophagy and ferroptosis in glioblastoma cells
Redox Biology, 2022 Objective: Glioblastoma is one of the most common intracranial malignant tumors with an unfavorable prognosis, and iron metabolism as well as ferroptosis are implicated in the pathogenesis of glioblastoma.
Kaiqiang Li +11 more
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MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma
Analytical Cellular Pathology, 2022 Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of various tumors, including the glioblastoma.
Peng Xu +7 more
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Glioblastoma: Changing concepts in the WHO CNS5 classification
Indian Journal of Pathology and Microbiology, 2022 Glioblastoma is the most common malignant central nervous system (CNS) tumor in adults. Acute common clinical symptoms include headache, seizure, behavior changes, focal neurological deficits, and signs of increased intracranial pressure. The classic MRI
Jie Chen, Pengcheng Han, Sonika Dahiya
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Biomedicines, 2021 Up to now, the chemotherapy approaches for glioblastoma were limited. 1-[2-Thiazolylazo]-2-naphthol (named as NSC139021) was shown to significantly inhibit the proliferation of prostate cancer cells by targeting the atypical protein kinase RIOK2.
Min Yu +5 more
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Glioblastoma Stem Cells as a New Therapeutic Target for Glioblastoma [PDF]
, 2015 Primary and secondary glioblastomas (GBMs) are two distinct diseases. The genetic and epigenetic background of these tumors is highly variable. The treatment procedure for these tumors is often unsuccessful because of the cellular heterogeneity and ...
Rasime Kalkan
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