Results 21 to 30 of about 358,441 (297)
TRIM7 modulates NCOA4-mediated ferritinophagy and ferroptosis in glioblastoma cells
Redox Biology, 2022 Objective: Glioblastoma is one of the most common intracranial malignant tumors with an unfavorable prognosis, and iron metabolism as well as ferroptosis are implicated in the pathogenesis of glioblastoma.
Kaiqiang Li +11 more
doaj +1 more source
Genetic alterations in gliosarcoma and giant cell glioblastoma [PDF]
, 2015 The majority of glioblastomas develop rapidly with a short clinical history (primary glioblastoma IDH wild-type), whereas secondary glioblastomas progress from diffuse astrocytoma or anaplastic astrocytoma.
ANTONELLI, MANILA +13 more
core +1 more source
Glioblastoma: Changing concepts in the WHO CNS5 classification
Indian Journal of Pathology and Microbiology, 2022 Glioblastoma is the most common malignant central nervous system (CNS) tumor in adults. Acute common clinical symptoms include headache, seizure, behavior changes, focal neurological deficits, and signs of increased intracranial pressure. The classic MRI
Jie Chen, Pengcheng Han, Sonika Dahiya
doaj +1 more source
Essential gene pathways for glioblastoma stem cells: clinical implications for prevention of tumor recurrence. [PDF]
, 2011 Glioblastoma (World Health Organization/WHO grade IV) is the most common and most aggressive adult glial tumor. Patients with glioblastoma, despite being treated with gross total resection and post-operative radiation/chemotherapy, will almost always ...
Choe, Jinny +6 more
core +1 more source
Biomedicines, 2021 Up to now, the chemotherapy approaches for glioblastoma were limited. 1-[2-Thiazolylazo]-2-naphthol (named as NSC139021) was shown to significantly inhibit the proliferation of prostate cancer cells by targeting the atypical protein kinase RIOK2.
Min Yu +5 more
doaj +1 more source
Arquivos de Neuro-Psiquiatria, 2007 Brain stem gliomas are a heterogeneous group of neoplasms arising mostly in paediatric patients. Tectal plate gliomas represent a particular type of brain stem tumours usually with a benign, indolent clinical course, presenting with signs of raised intracranial hipertension due to supra-tentorialhydrocephalous caused by aqueductal stenosis. Seldom high-
Chaddad Neto, Feres +5 more
openaire +4 more sources
GBM heterogeneity as a function of variable epidermal growth factor receptor variant III activity. [PDF]
, 2016 Abnormal activation of the epidermal growth factor receptor (EGFR) due to a deletion of exons 2-7 of EGFR (EGFRvIII) is a common alteration in glioblastoma (GBM). While this alteration can drive gliomagenesis, tumors harboring EGFRvIII are heterogeneous.
David James, C +11 more
core +1 more source
MicroRNA-147a Targets SLC40A1 to Induce Ferroptosis in Human Glioblastoma
Analytical Cellular Pathology, 2022 Objective. Glioblastoma is one of the most common malignant tumors in the brain, and these glioblastoma patients have very poor prognosis. Ferroptosis is involved in the progression of various tumors, including the glioblastoma.
Peng Xu +7 more
doaj +1 more source
Research Progress of Diagnosis and Treatment of Glioblastoma
Zhongliu Fangzhi Yanjiu, 2022 Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
doaj +1 more source
Severe and prolonged myelosuppression during concomitant temozolomide and radiotherapy treatment in a patient with glioblastoma multiforme [PDF]
, 2015 Aims: We describe the case of a patient with glioblastoma (GBM) who developed severe and prolonged myelosuppression during concomitant daily temozolomide (TMZ) and radiotherapy (RT) treatment.
ALOE SPIRITI, Maria Antonietta +12 more
core +1 more source