Results 21 to 30 of about 222,357 (321)
AbstractElevated levels of serum ferritin (SF) are observed in several types of cancer; however, little is known on the association between ferritin and glioma, the most frequent type of human primary brain tumour. Here we report that GBM patients show significantly increased pre-surgical SF levels (i.e. ferritinaemia) within the SF reference range and
Paolo Arosio+9 more
openaire +3 more sources
Suppressing Dazl modulates tumorigenicity and stemness in human glioblastoma cells
Background Glioblastoma is devastating cancer with a high frequency of occurrence and poor survival rate and it is urgent to discover novel glioblastoma-specific antigens for the therapy. Cancer-germline genes are known to be related to the formation and
Fengyu Zhang+5 more
doaj +1 more source
BackgroundStudies have shown that the immune infiltration of tumor microenvironment is related to the prognosis of glioblastoma, which is characterized by high heterogeneity, high recurrence rate and low survival rate.
YingHao Luo+7 more
doaj +1 more source
Treatment planning with a 2.5 MV photon beam for radiation therapy
Abstract Purpose The shallow depth of maximum dose and higher dose fall‐off gradient of a 2.5 MV beam along the central axis that is available for imaging on linear accelerators is investigated for treatment of shallow tumors and sparing the organs at risk (OARs) beyond it.
Navid Khaledi+5 more
wiley +1 more source
. Background. Previous studies have demonstrated that various circular RNAs are involved in the malignant proliferation of cancers, such as liver cancer, lung cancer, breast cancer, and others. The potential role of circular RNAs in glioblastoma, however,
Jin-Xu Zhou+8 more
doaj +1 more source
Optimization of Tumor Targeting Gold Nanoparticles for Glioblastoma Applications
Glioblastoma brain tumors represent an aggressive form of gliomas that is hallmarked by being extremely invasive and aggressive due to intra and inter-tumoral heterogeneity.
Nicholas C. Allen+3 more
doaj +1 more source
Glioblastoma: Changing concepts in the WHO CNS5 classification
Glioblastoma is the most common malignant central nervous system (CNS) tumor in adults. Acute common clinical symptoms include headache, seizure, behavior changes, focal neurological deficits, and signs of increased intracranial pressure. The classic MRI
Jie Chen, Pengcheng Han, Sonika Dahiya
doaj +1 more source
Elucidation of cellular and molecular mechanisms key to glioblastoma growth, self-renewal, survival, and metastasis is important for developing novel therapeutic strategies.
Yan Wang+4 more
doaj
Up to now, the chemotherapy approaches for glioblastoma were limited. 1-[2-Thiazolylazo]-2-naphthol (named as NSC139021) was shown to significantly inhibit the proliferation of prostate cancer cells by targeting the atypical protein kinase RIOK2.
Min Yu+5 more
doaj +1 more source
Immunotherapy is currently under intensive investigation as a potential breakthrough treatment option for glioblastoma. Given the anatomical and immunological complexities surrounding glioblastoma, lymphocytes that infiltrate the brain to develop durable
Jorrit De Waele+7 more
doaj +1 more source