Results 31 to 40 of about 11,735 (173)
Characterising Distinct Migratory Profiles of Infiltrating T-Cell Subsets in Human Glioblastoma
Glioblastoma is the most common and aggressive form of primary brain cancer, with no improvements in the 5-year survival rate of 4.6% over the past three decades.
Paris M. Kollis+20 more
doaj +1 more source
A variety of drugs targeting monoamine receptors are routinely used in human pharmacology. We assessed the effect of these drugs on the viability of tumor‐initiating cells isolated from patients with glioblastoma.
Suzana Assad Kahn+18 more
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The study of survival outliers of glioblastoma can provide important clues on gliomagenesis as well as on the ways to alter clinical course of this almost uniformly lethal cancer type.
Taeyoung Hwang+12 more
doaj +1 more source
Research Progress of Diagnosis and Treatment of Glioblastoma
Glioblastoma is the most common primary malignant brain tumor. Despite large-scale researches have been carried out, the prognosis of glioblastoma is still not significantly improved.
CHEN Qianxue
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Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto+3 more
doaj +1 more source
Glioblastoma is a malignant brain tumor and one of the most lethal cancers in human. Temozolomide constitutes the standard chemotherapeutic agent, but only shows limited efficacy in glioblastoma patients with unmethylated O-6-methylguanine-DNA ...
Matthias Schneider+16 more
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MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma
Background Glioblastoma is a malignant brain tumor characterized by rapid growth, diffuse invasion and therapeutic resistance. We recently used microRNA expression profiles to subclassify glioblastoma into five genetically and clinically distinct ...
Yun Zhao+10 more
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The Role of NKT Cells in Glioblastoma
Glioblastoma is an aggressive and deadly cancer, but to date, immunotherapies have failed to make significant strides in improving prognoses for glioblastoma patients.
Emily E. S. Brettschneider+1 more
doaj +1 more source
Identification of novel small molecule inhibitors of ETS transcription factors
ETS transcription factors play an essential role in tumourigenesis and are indispensable for sprouting angiogenesis, a hallmark of cancer, which fuels tumour expansion and dissemination. Thus, targeting ETS transcription factor function could represent an effective, multifaceted strategy to block tumour growth. The evolutionarily conserved E‐Twenty‐Six
Shaima Abdalla+9 more
wiley +1 more source
Surfaceome: a new era in the discovery of immune evasion mechanisms of circulating tumor cells
In the era of immunotherapies, many patients either do not respond or eventually develop resistance. We propose to pave the way for proteomic analysis of surface‐expressed proteins called surfaceome, of circulating tumor cells. This approach seeks to identify immune evasion mechanisms and discover potential therapeutic targets. Circulating tumor cells (
Doryan Masmoudi+3 more
wiley +1 more source