Results 51 to 60 of about 319,103 (346)

Glioblastoma

open access: yesArchives of Pathology & Laboratory Medicine, 2007
Abstract Context.—Glioblastoma (GBM), the most common primary intracranial malignancy, is a morphologically diverse neoplasm with dismal prognosis despite multimodality therapy. Only 3 distinct morphologic variants of GBM are currently recognized by the current World Health Organization classification scheme, including GBM, giant cell ...
C. Ryan Miller, Arie Perry
openaire   +3 more sources

Trying to Kill a Killer; Impressive Killing of Patient Derived Glioblastoma Cultures Using NK-92 Natural Killer Cells Reveals Both Sensitive and Highly Resistant Glioblastoma Cells

open access: yesCells
The overall goal of this work was to assess the ability of Natural Killer cells to kill cultures of patient-derived glioblastoma cells. Herein we report impressive levels of NK-92 mediated killing of various patient-derived glioblastoma cultures observed
Jane Yu   +7 more
doaj   +1 more source

Gliosarcoma Transforming from Giant Cell Glioblastoma: A Case Report and Review of the Literature

open access: yesHaseki Tıp Bülteni, 2019
Giant cell glioblastoma and gliosarcoma are rare histological variants of glioblastoma multiforme. These are WHO Grade IV astrocytic tumors. While giant cell glioblastoma can be seen at younger age, gliosarcoma typically presents at age 40-60 years ...
Elife Kımıloğlu   +3 more
doaj   +1 more source

MicroRNA-29a activates a multi-component growth and invasion program in glioblastoma

open access: yesJournal of Experimental & Clinical Cancer Research, 2019
Background Glioblastoma is a malignant brain tumor characterized by rapid growth, diffuse invasion and therapeutic resistance. We recently used microRNA expression profiles to subclassify glioblastoma into five genetically and clinically distinct ...
Yun Zhao   +10 more
doaj   +1 more source

Valganciclovir as Add-On to Standard Therapy in Secondary Glioblastoma

open access: yesMicroorganisms, 2020
Patients with glioblastoma have a very poor prognosis despite aggressive therapeutic strategies. Cytomegalovirus has been detected in >90% of glioblastoma tumors.
Giuseppe Stragliotto   +3 more
doaj   +1 more source

Glioblastoma cell-secreted interleukin-8 induces brain endothelial cell permeability via CXCR2. [PDF]

open access: yesPLoS ONE, 2012
Glioblastoma constitutes the most aggressive and deadly of brain tumors. As yet, both conventional and molecular-based therapies have met with limited success in treatment of this cancer.
Julie Dwyer   +8 more
doaj   +1 more source

Xantoastrocitoma pleomórfico anaplásico y glioblastoma epitelioide: misma entidad o precursor de enfermedad

open access: yesMedUNAB, 2021
RESUMEN Introducción. El xantoastrocitoma pleomórfico es una lesión glial de bajo grado de malignidad (grado II), puede presentar transformación maligna progresando a xantoastrocitoma pleomórfico anaplásico o glioblastoma multiforme, clasificados en ...
María Alejandra Baquero-Serrano   +2 more
doaj   +1 more source

Decoding the dual role of autophagy in cancer through transcriptional and epigenetic regulation

open access: yesFEBS Letters, EarlyView.
Transcriptional and epigenetic regulation controls autophagy, which exerts context‐dependent effects on cancer: Autophagy suppresses tumorigenesis by maintaining cellular homeostasis or promotes tumor progression by supporting survival under stress. In this “In a Nutshell” article, we explore the intricate mechanisms of the dual function of autophagy ...
Young Suk Yu, Ik Soo Kim, Sung Hee Baek
wiley   +1 more source

Implication of tumor morphology and MRI characteristics on the accuracy of automated versus human segmentation of GBM areas

open access: yesScientific Reports
An assessment scheme is proposed to evaluate GBM gross tumor core and T2-FLAIR hyper-intensity segmentations on preoperative multicentric MR images as a function of tumor morphology and MRI characteristics.
Valeria Cerina   +7 more
doaj   +1 more source

A novel circular RNA circENTPD7 contributes to glioblastoma progression by targeting ROS1

open access: yesCancer Cell International, 2020
Background Circular RNAs (circRNAs) are identified to play an important role in many human cancers, such as glioblastoma. However, the potential mechanisms underlying the relationship between circRNAs and glioblastoma pathogenesis are still elusive. This
Fei Zhu   +4 more
doaj   +1 more source

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