Results 171 to 180 of about 114,018,569 (202)

Metabolic and Post-Translational Vulnerabilities of Glioblastoma: Disulfidptosis, Glycosylation, and Implications for CAR-T Therapy. [PDF]

Cells
Strózik T, Rutkowska A, Wasiak T, Ciunowicz D, Rieske P, Szczepaniak N, Stoczyńska-Fidelus E.   +6 more
europepmc   +1 more source

Chronic IFN-γ Exposure Induces Divergent Adaptive Programs in Glioblastoma Subtypes. [PDF]

Cancers (Basel)
Rahbarlayegh E, Nomura N, Juarez TM, Kesari PR, Kesari S.   +4 more
europepmc   +1 more source

Identification of drug candidates against glioblastoma with machine learning and high-throughput screening of heterogeneous cellular models.

Digit Discov
Smer-Barreto V, Elliott RJR, Dawson JC, Lorente-Macías Á, Furqan M, Unciti-Broceta A, Oyarzún DA, Carragher NO.   +7 more
europepmc   +1 more source

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Combination of SIX4-siRNA and temozolomide inhibits the growth and migration of A-172 glioblastoma cancer cells

Naunyn-Schmiedeberg's Archives of Pharmacology, 2023
Glioblastoma is one of the most common and invasive types of primary brain malignancies in adults, accounting for 45.5% of malignancies. Its annual prevalence is low compared to other cancers. The survival rate of this disease is about 14 months after diagnosis.
Zahra Jodari, Mohammadpour, Reza, Mohammadzadeh, Darya, Javadrashid, Amir, Baghbanzadeh, Mohammad Amin, Doustvandi, Nesa, Barpour, Behzad, Baradaran   +6 more
openaire   +2 more sources

Investigation of the Role of Induced Overexpression of the Isolated Secreted Klotho on the A-172 Human Glioblastoma Cells

Journal of Molecular Neuroscience, 2022
Klotho gene, identified in 1997 as an anti-aging gene, can manufacture two protein products: transmembrane and secreted forms. The later research revealed the involvement of klotho in carcinogenesis. However, little is known about the action of different Klotho forms on antitumor effects is still.
Vsevolod V. Melekhin, Alexander I. Ponomarev, Maria A. Desyatova, Oleg G. Makeev   +3 more
openaire   +2 more sources

Immunocytochemical studies on the effect of 405-nm low-power laser irradiation on human-derived A-172 glioblastoma cells

Lasers in Medical Science, 2011
The application of low-power laser irradiation (LLI) affects the cell cycle and cell proliferation in various kinds of cells. LLI at a wavelength of 808 nm and a power of 30 mW has been found to significantly decrease the proliferation rate of cells of the human-derived glioblastoma cell line A-172. To determine if this effect of LLI is specific to 808-
Foong Yee, Ang, Yumi, Fukuzaki, Banri, Yamanoha, Shinichi, Kogure   +3 more
openaire   +2 more sources

PS2 - 172 Preclinical Validation of a Novel CD33/CD3 Bispecific T-Cell Engager (BiTE) Antibody to Target Patient-Derived Glioblastoma Cells

Canadian Journal of Neurological Sciences / Journal Canadien des Sciences Neurologiques, 2016
Glioblastoma (GBM), an aggressive primary adult brain tumor, is feared for its near uniformly fatal prognosis. Despite the use of aggressive treatment including surgical resection, radiotherapy and chemotherapy, the outcome of patients with GBM has failed to improve significantly.
P. Vora, C. Venugopal, C. Choksi, M. Qazi, J. Adams, M. London, M. Subapanditha, M. Singh, D. Bakshinyan, S. Sidhu, J. Moffat, S. Singh   +11 more
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Cloning and functional expression of human inducible nitric oxide synthase (NOS) cDNA from a glioblastoma cell line A-172.

Journal of biochemistry, 1995
Nitric oxide (NO) is a messenger molecule with diverse functions throughout the body. The inducible type of nitric oxide synthase (NOS) is considered to be a key molecule in the immune responses to bacteria, parasites, and tumors, and its gene expression is regulated by cytokines. We isolated 3 overlapping partial inducible NOS cDNA clones from a human
A, Hokari, M, Zeniya, H, Esumi
openaire   +1 more source