Results 51 to 60 of about 114,018,569 (202)
Development of armed oncolytic agents based on the herpes simplex virus type 1 for the treatment of glioblastoma [PDF]
, 2023 openGlioblastoma (GBM) is one of the most common and aggressive malignant brain tumors in adults. Patients affected by glioblastoma show poor prognosis and low survival rate after the diagnosis.
ZAGO, ALESSIA
core
Advanced Science, EarlyView.This review elucidates how cancer cell metabolic reprogramming—across glucose, lipid, amino acid, and nucleotide pathways—remodels the tumor microenvironment to suppress anti‐tumor immunity and promote immune escape. Targeting these metabolic axes offers promising strategies to overcome immunotherapy resistance and enhance cancer treatment.
Guoqing Xiang +5 more
wiley +1 more source
EGF receptor-targeted synthetic double-stranded RNA eliminates glioblastoma, breast cancer, and adenocarcinoma tumors in mice [PDF]
, 2005 Background: Glioblastoma multiforme (GBM) is the most lethal form of brain cancer. With the available treatments, survival does not exceed 12–14 mo from the time of diagnosis.
Levitzki, Alexander +15 more
core +2 more sources
Screen for IDH1, IDH2, IDH3, D2HGDH and L2HGDH mutations in glioblastoma.
PLoS ONE, 2011 Isocitrate dehydrogenases (IDHs) catalyse oxidative decarboxylation of isocitrate to α-ketoglutarate (α-KG). IDH1 functions in the cytosol and peroxisomes, whereas IDH2 and IDH3 are both localized in the mitochondria.
Daniel Krell +5 more
doaj +1 more source
Advanced Science, EarlyView.This review redefines radiotherapy‐triggered drug delivery systems through structural disassembly and molecular actuation, proposing a translation‐oriented framework for dose‐correlated activation to advance clinically integrated precision oncology. ABSTRACT Radiotherapy‐triggered drug delivery systems (RDDS) promise to integrate the spatial precision ...
Jianv Jiang +3 more
wiley +1 more source
OncoImmunologyGlioblastoma multiforme (GBM) is a highly aggressive primary brain tumor characterized by poor prognosis and lack of effective treatments. In recent years, peptide vaccines that use sequences based on tumor-specific or tumor-associated antigens to activate immune responses against tumor cells have emerged as a new therapeutic strategy.
Shan Wang +11 more
openaire +3 more sources
Leveraging Microphysiological Systems to Facilitate Neutrophil‐Based Cancer Immunotherapy
Advanced Science, EarlyView.Microphysiological systems are emerging as powerful human‐relevant platforms for studying neutrophil biology in cancer. Current applications of spheroids, organoids, and organ‐on‐a‐chip models are reviewed, together with future opportunities in behaviorome profiling, multi‐omics integration, personalized medicine, immune crosstalk, and multi‐organ ...
Shuai Shao +2 more
wiley +1 more source
Surgery of brain tumors in the older persons [PDF]
, 2014 Rozumenko V. D., Yavorskiy A. A. Surgery of brain tumors in the older persons. Journal of Health Sciences. 2014;4(14):45-49. ISSN 1429-9623 / 2300-665X. http://journal.rsw.edu.pl/index.php/JHS/article/view/2014%3B4%2814%29%3A45-49 http://ojs.ukw.edu.pl/
Rozumenko, V. D., Yavorskiy, A. A.
core +1 more source
Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
Frontiers in OncologyBackgroundCancer is a global health problem accounting for nearly one in six deaths worldwide. Conventional treatments together with new therapies have increased survival to this devastating disease.
Diego Iglesias-Corral +23 more
doaj +1 more source
BMEMat, EarlyView.Ultrasound‐responsive nanoplatforms reprogram the tumor immune microenvironment by targeting tumor cells, immune cells, and non‐immune stromal cells to enhance the efficacy of cancer immunotherapy. Abstract Cancer immunotherapy represents a significant advancement in cancer treatment by enhancing the specific recognition and elimination of cancer cells.
Shilong Zhao +4 more
wiley +1 more source