Results 101 to 110 of about 412,622 (340)

Matrix: a complex amalgam of structures and functions in tumor microenvironment

FEBS Open Bio, EarlyView.
The matrix is a dynamic, intricate three‐dimensional mesh of biomolecules with both structural and functional properties. This review deals with the complexity of this ‘molecular amalgam’ in the tumor microenvironment and highlights its importance in the maintenance and evolution of tumors by describing certain matrix biomolecules, such as ...
Spyros S. Skandalis, Evgenia Tsoukala, Theodora D. Sarantopoulou, Maria‐Elpida Christopoulou   +3 more
wiley   +1 more source

East meets West for the treatment of glioma: A discussion of real-world cases

Glioma, 2020
Background and Aim: The standard of care for patients with gliomas should follow established guidelines. In real-world management, however, the management sometimes deviates from these guidelines.
Haozhe Piao, Ye Zhang, Chengcheng Guo, Li Zhu, Linan Liu, Ulrich Herrlinger, Felix Sahm, Zhong-ping Chen   +7 more
doaj   +1 more source

Optical biopsy identification and grading of gliomas using label-free visible resonance Raman spectroscopy. [PDF]

, 2019
Glioma is one of the most refractory types of brain tumor. Accurate tumor boundary identification and complete resection of the tumor are essential for glioma removal during brain surgery.
Alfano, Robert R, Cheng, Gangge, Liu, Cheng-Hui, Shi, Lingyan, Wang, Kai, Wu, Binlin, Yu, Xinguang, Zhang, Chunyuan, Zhang, Lin, Zhao, Mingyue, Zhou, Yan, Zhu, Ke, Zong, Rui   +12 more
core   +1 more source

Protein kinase a distribution differentiates human glioblastoma from brain tissue [PDF]

, 2017
Brain tumor glioblastoma has no clear molecular signature and there is no effective therapy. In rodents, the intracellular distribution of the cyclic AMP (cAMP)-dependent protein kinase (Protein kinase A, PKA) R2Alpha subunit was previously shown to ...
Caretta, Antonio, D\u2019Avella, Domenico, Denaro, Luca, Mucignat-Caretta, Carla   +3 more
core   +2 more sources

Liver‐specific lncRNAs associated with liver cancers

FEBS Open Bio, EarlyView.
Long non‐coding RNAs (lncRNAs) are regulatory molecules with various functions. They are more tissue‐specific than proteins and can be used as potential biomarkers, particularly in cancer diagnostics and prognosis. In this review, we have systematically compiled all lncRNAs with exclusive expression in the human liver, verified their liver specificity ...
Olga Y. Burenina, Roman K. Makarchenko, Maria P. Rubtsova, Olga A. Dontsova   +3 more
wiley   +1 more source

A rare case of gliosarcoma after acute hemorrhage

Glioma, 2019
Gliosarcoma (GSM) is a rare primary neoplasm of the brain, characterized by a biphasic tissue pattern with alternating areas displaying glial and mesenchymal differentiation.
Yunni Diansari, Satalina Mutiara, Hasan Baraqbah, Mediarty Syahrir, Hanna Marsinta, Asfitriani Erwin, Dini Andriani   +6 more
doaj   +1 more source

Environmental stimuli shape microglial plasticity in glioma [PDF]

, 2017
In glioma, microglia and infiltrating macrophages are exposed to factors that force them to produce cytokines and chemokines, contributing to tumor growth and maintaining a pro-tumorigenic, immunosuppressed microenvironment.
Alboni, Armaiz-Pena, Bisht, Branchi, Butovsky, Cao, Chabry, Coniglio, Coughlin, Duluc, Dunn, Ehninger, Ehninger, Gabrusiewicz, Garofalo, Goldszmid, Graeber, Guillerey, Hambardzumyan, Haynes, Jung, Kaplan, Kmiecik, Kmiecik, Koka, Lauro, Mantovani, Markovic, Markovic, Mathios, Mieczkowski, Morrison, Murray, Nachat-Kappes, Nguyen, Ohsawa, Pagani, Parker, Pyonteck, Quail, Rattazzi, Richter, Rodríguez, Sale, Schmittgen, Sica, Sierra, Song, Stabile, Strengell, Szulzewsky, Szulzewsky, Tremblay, Tremblay, Van Rooijen, Vivier, Waldmann, Westwood, Yu, Zhu   +59 more
core   +2 more sources

Cognitive and Patient‐Reported Outcome Measures in LGI‐1‐IgG Autoimmune Encephalitis

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Clinical outcome measures for autoimmune encephalitis (AE) are not yet well defined. Cognitive outcome measures (CogOs) and patient‐reported outcomes (PROs) may capture the symptoms of AE, beyond clinician‐reported outcomes (ClinROs) (the Modified Rankin Scale [mRS] and Clinical Assessment Scale in Autoimmune Encephalitis [CASE ...
Tatchaporn Ongphichetmetha, Carol Swetlik, Nicolas Thompson, Albert Aboseif, Vineet Punia, Brittany Lapin, Jeffrey A. Cohen, Rachel Galioto, Amy Kunchok   +8 more
wiley   +1 more source

Survivin a radiogenetic promoter for glioblastoma viral gene therapy independently from CArG motifs [PDF]

, 2017
BACKGROUND: Radiogenetic therapy is a novel approach in the treatment of cancer, which employs genetic modification to alter the sensitivity of tumor cells to the effect of applied radiation.
Arafat WO, Arafat WO, Datta R, Deb P, Fiveash JB, Hsu H, Kanzawa T, Kawakami Y, Kufe D, Nandi S, Nenoi M, Nieder C, Pinsker M, Rosenfeld ME, Sonabend AM, Tsai‐Morris CH, Weichselbaum RR   +16 more
core   +2 more sources

The Regulation of Trace Metal Elements in Cancer Ferroptosis

Advanced Biology, EarlyView.
The induction of ferroptosis inhibits tumor growth, enhances anticancer efficacy, and overcomes drug resistance. Recent evidence shows nonferrous metal elements play a role in ferroptosis. This review focuses on how trace metals regulate ferroptosis processes like iron accumulation, lipid peroxidation, and antioxidant defense.
Xiaoyan Wang, Yuanyuan Xue, Lei Chang, Xuena Zhu, Wenjun Liu, Tingbo Liang   +5 more
wiley   +1 more source