Results 31 to 40 of about 437,642 (362)

Silencing expression of PHF14 in glioblastoma promotes apoptosis, mitigates proliferation and invasiveness via Wnt signal pathway

Cancer Cell International, 2019
Background The plant homeodomain (PHD) finger protein 14 (PHF14) is a vital member of PHD finger protein families. Abnormal expression of PHF14 has been identified in various cancers and is known to be implicated in the pathogenesis of tumors. This study
Shuai Wu, Chen Luo, Fengjiao Li, N. U. Farrukh Hameed, Qiuyan Jin, Jie Zhang   +5 more
doaj   +1 more source

An online survival predictor in glioma patients using machine learning based on WHO CNS5 data

Frontiers in Neurology, 2023
BackgroundThe World Health Organization (WHO) CNS5 classification system highlights the significance of molecular biomarkers in providing meaningful prognostic and therapeutic information for gliomas.
Liguo Ye, Lingui Gu, Zhiyao Zheng, Zhiyao Zheng, Zhiyao Zheng, Xin Zhang, Hao Xing, Xiaopeng Guo, Xiaopeng Guo, Wenlin Chen, Yaning Wang, Yuekun Wang, Tingyu Liang, Hai Wang, Yilin Li, Yilin Li, Shanmu Jin, Shanmu Jin, Yixin Shi, Yixin Shi, Delin Liu, Delin Liu, Tianrui Yang, Tianrui Yang, Qianshu Liu, Qianshu Liu, Congcong Deng, Yu Wang, Yu Wang, Wenbin Ma, Wenbin Ma   +30 more
doaj   +1 more source

Mathematical model of brain tumour with glia-neuron interactions and chemotherapy treatment [PDF]

, 2015
Acknowledgements This study was possible by partial financial support from the following Brazilian government agencies: Fundação Araucária, EPSRC-EP/I032606/1 and CNPq, CAPES and Science Without Borders Program Process nos. 17656125, 99999.010583/2013-00
Baptista, Murilo Da Silva, Baptista, Murilo S., Batista, Antonio M., Borges, Fernando S., Iarosz, Kelly C., Lopes, Sergio R., Siqueira, Regiane A. N., Viana, Ricardo L.   +7 more
core   +1 more source

Axitinib induces senescence-associated cell death and necrosis in glioma cell lines: The proteasome inhibitor, bortezomib, potentiates axitinib-induced cytotoxicity in a p21(Waf/Cip1) dependent manner. [PDF]

, 2017
Glioblastoma is associated with a poor overall survival despite new treatment advances. Antiangiogenic strategies targeting VEGF based on tyrosine kinase inhibitors (TKIs) are currently undergoing extensive research for the treatment of glioma.
Amantini, C, BERNARDINI, Giovanni, CARDINALI, CLAUDIO, MORELLI, MARIA BEATRICE, Nabissi, M, SANTONI, Angela, Santoni, G., Santoni, M   +7 more
core   +1 more source

NK Cell-Based Immunotherapy and Therapeutic Perspective in Gliomas

Frontiers in Oncology, 2021
Glioma is the most common malignant primary brain tumor diagnosed in adults. Current therapies are unable to improve its clinical prognosis, imposing the need for innovative therapeutic approaches. The main reason for the poor prognosis is the great cell
Changqing Pan, You Zhai, Guanzhang Li, Tao Jiang, Tao Jiang, Tao Jiang, Tao Jiang, Wei Zhang, Wei Zhang, Wei Zhang, Wei Zhang   +10 more
doaj   +1 more source

Initial report of a clinical trial evaluating the safety and efficiency of neoadjuvant camrelizumab and apatinib in patients with recurrent high-grade gliomas: A prospective, phase II, single-arm study

Glioma, 2022
Background and Aim: High-grade glioma is the most common malignant primary brain tumor in the central nervous system. Multiple strategies such as surgery, radiotherapy, and chemotherapy have been used, but the prognosis of patients with high-grade glioma
Fuhua Lin, Chengcheng Guo, Qunying Yang, Yinsheng Chen, Chao Ke, Ke Sai, Ji Zhang, Xiaobing Jiang, Wanming Hu, Shaoyan Xi, Jian Zhou, Depei Li, Zhihuan Zhou, Qinqin Zhao, Xi Cao, Zhong-ping Chen   +15 more
doaj   +1 more source

Clinical, radiologic, pathologic, and molecular characteristics of long-term survivors of diffuse intrinsic pontine glioma (DIPG): a collaborative report from the International and European Society for Pediatric Oncology DIPG registries [PDF]

, 2018
Purpose Diffuse intrinsic pontine glioma (DIPG) is a brainstem malignancy with a median survival of < 1 year. The International and European Society for Pediatric Oncology DIPG Registries collaborated to compare clinical, radiologic, and ...
Antonelli, Manila, Antonelli, Manila, Bailey, Simon, Bartels, Ute, Baugh, Joshua, Benesch, Martin, Biassoni, Veronica, Bison, Brigitte, Boddaert, Nathalie, Bouffet, Eric, Broniscer, Alberto, Broxson, Emmett, Calmon, Raphael, Castel, David, Chaney, Brooklyn, Chintagumpala, Murali, Colditz, Niclas, Comito, Melanie, Dholaria, Hetal, Doughman, Renee, Drissi, Rachid, Foreman, Nicholas K., Fouladi, Maryam, Fuller, Christine, Gerber, Nicolas U., Giagnacovo, Marzia, Gielen, Gerrit H., Giraud, G´eraldine, Goldman, Stewart, Gottardo, Nicholas, Grill, Jacques, Grotzer, Michael A., Hargrave, Darren, Hassall, Timothy, Hawkins, Cynthia, Hoffman, Lindsey M., Hoffmann, Marion, Hulleman, Esther, Jabado, Nada, Jadrijevic Cvrlje, Filip, Jones, Blaise, Jones, Chris, Jones, David T. W., Kaspers, Gertjan J. L., Khatua, Soumen, Kieran, Mark W., Kramm, Christof M., Lane, Adam, Leach, James, Leary, Sarah, Massimino, Maura, Miles, Lili, Minturn, Jane, Modena, Piergiorgio, Nazarian, Javad, Packer, Roger, Pfaff, Elke, Pfister, Stefan M., Pietsch, Torsten, Puget, Stephanie, Sanchez, Esther, Shih, Chie-Schin, Solanki, Guirish A., Sophie Carret, Anne, Sturm, Dominik, van Vuurden, Dannis G., Vandertop, William P., Varlet, Pascale, Veldhuijzen van Zanten, Sophie E. M., von Bueren, Andr´e O., Warmuth-Metz, Monika, Warren, Katherine E., Yanez Escorza, Nancy, Ziegler, David S.   +73 more
core   +4 more sources

Novel insight into histological and molecular astrocytoma, IDH‐mutant, Grade 4 by the updated WHO classification of central nervous system tumors

Cancer Medicine, 2023
Background The latest fifth edition of the World Health Organization (WHO) classification of the central nervous system (CNS) tumors (WHO CNS 5 classification) released in 2021 defined astrocytoma, IDH‐mutant, Grade 4.
Wenlin Chen, Siying Guo, Yaning Wang, Yixin Shi, Xiaopeng Guo, Delin Liu, Yilin Li, Yuekun Wang, Hao Xing, Yu Xia, Junlin Li, Jiaming Wu, Tingyu Liang, Hai Wang, Qianshu Liu, Shanmu Jin, Tian Qu, Huanzhang Li, Tianrui Yang, Kun Zhang, Yu Wang, Wenbin Ma   +21 more
doaj   +1 more source

Immune factors preceding diagnosis of glioma: a Prostate Lung Colorectal Ovarian Cancer Screening Trial nested case-control study. [PDF]

, 2019
BackgroundEpidemiological studies of adult glioma have identified genetic and environmental risk factors, but much remains unclear. The aim of the current study was to evaluate anthropometric, disease-related, and prediagnostic immune-related factors for
Bracci, Paige M, Gauderman, W James, Hansen, Helen M, Mccoy, Lucie, Muskens, Ivo S, Wiemels, Joseph L, Wiencke, John K, Wrensch, Margaret R, Zhou, Mi   +8 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source